| Protein: | MEX67 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 599 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MEX67.
| Description | E-value | Query Range |
Subject Range |
|
|
5.0E-87 | [14..598] | [110..618] |
|
|
2.0E-85 | [14..598] | [111..619] |
|
|
5.0E-85 | [14..598] | [110..618] |
|
|
1.0E-77 | [4..490] | [23..516] |
|
Region A: Residues: [1-98] |
1 11 21 31 41 51
| | | | | |
1 MSGFHNVGNI NMMAQQQMQQ NRIKISVRNW QNATMNDLIN FISRNARVAV YDAHVEGPLV 60
61 IGYVNSKAEA ESLMKWNGVR FAGSNLKFEL LDNNGASA
|
| Detection Method: |  |
| Confidence: | 118.927757 |
| Match: | 1ft8A_ |
| Description: | mRNA export factor tap |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor activity | 2.45747497442245 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.20259885800343 | bayes_pls_golite062009 |
| signal transducer activity | 2.14481842394036 | bayes_pls_golite062009 |
| molecular transducer activity | 2.14481842394036 | bayes_pls_golite062009 |
| binding | 1.87302803330255 | bayes_pls_golite062009 |
| structural molecule activity | 1.83189461928225 | bayes_pls_golite062009 |
| nucleic acid binding | 1.5811568573961 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 1.43652168420174 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.2741906444944 | bayes_pls_golite062009 |
| actin binding | 0.666110887282576 | bayes_pls_golite062009 |
| protein binding | 0.646159692466759 | bayes_pls_golite062009 |
|
Region A: Residues: [99-260] |
1 11 21 31 41 51
| | | | | |
1 GTSDTISFLR GVLLKRYDPQ TKLLNLGALH SDPELIQKGV FSSISTQSKM FPAMMKLAST 60
61 EKSLIVESVN LADNQLKDIS AISTLAQTFP NLKNLCLANN QIFRFRSLEV WKNKFKDLRE 120
121 LLMTNNPITT DKLYRTEMLR LFPKLVVLDN VIVRDEQKLQ TV
|
| Detection Method: | |
| Confidence: | 118.927757 |
| Match: | 1ft8A_ |
| Description: | mRNA export factor tap |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [261-375] |
1 11 21 31 41 51
| | | | | |
1 YSLPMKIQQF FFENDALGQS STDFATNFLN LWDNNREQLL NLYSPQSQFS VSVDSTIPPS 60
61 TVTDSDQTPA FGYYMSSSRN ISKVSSEKSI QQRLSIGQES INSIFKTLPK TKHHL
|
| Detection Method: | |
| Confidence: | 21.221849 |
| Match: | 1p8tA_ |
| Description: | Reticulon 4 receptor (Nogo-66 receptor, Ngr) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleocytoplasmic transporter activity | 4.11811310168752 | bayes_pls_golite062009 |
| protein transporter activity | 3.25560675565407 | bayes_pls_golite062009 |
| binding | 2.52411158739487 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 2.19585939185279 | bayes_pls_golite062009 |
| structural constituent of nuclear pore | 2.18859566641856 | bayes_pls_golite062009 |
| nucleic acid binding | 2.1539951593359 | bayes_pls_golite062009 |
| transporter activity | 1.80701285041353 | bayes_pls_golite062009 |
| structural molecule activity | 1.60851232976006 | bayes_pls_golite062009 |
| mRNA binding | 1.48678274024408 | bayes_pls_golite062009 |
| protein binding | 1.34243535208605 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.33804818542017 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.22102896992563 | bayes_pls_golite062009 |
| Ran GTPase binding | 1.18290069522408 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.890150150408175 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven protein transmembrane transporter activity | 0.77053580490303 | bayes_pls_golite062009 |
| macromolecule transmembrane transporter activity | 0.77053580490303 | bayes_pls_golite062009 |
| RNA binding | 0.47499792472996 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 0.446562877324676 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.439519001457896 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.430285640125175 | bayes_pls_golite062009 |
|
Region A: Residues: [376-445] |
1 11 21 31 41 51
| | | | | |
1 QEQPNEYSME TISYPQINGF VITLHGFFEE TGKPELESNK KTGKNNYQKN RRYNHGYNST 60
61 SNNKLSKKSF
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [446-599] |
1 11 21 31 41 51
| | | | | |
1 DRTWVIVPMN NSVIIASDLL TVRAYSTGAW KTASIAIAQP PQQQASVLPQ VASMNPNITT 60
61 PPQPQPSVVP GGMSIPGAPQ GAMVMAPTLQ LPPDVQSRLN PVQLELLNKL HLETKLNAEY 120
121 TFMLAEQSNW NYEVAIKGFQ SSMNGIPREA FVQF
|
| Detection Method: | |
| Confidence: | 39.69897 |
| Match: | 1jkgB_ |
| Description: | NTF2-like domain of Tip associating protein, TAP |
Matching Structure (courtesy of the PDB): |
|
