| Protein: | PEP4 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 405 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEP4.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [4..403] | [1..384] |
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0.0 | [4..403] | [1..383] |
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0.0 | [4..403] | [2..385] |
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0.0 | [4..403] | [1..386] |
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0.0 | [4..404] | [1..395] |
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0.0 | [4..405] | [1..380] |
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0.0 | [4..403] | [1..384] |
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Region A: Residues: [1-74] |
1 11 21 31 41 51
| | | | | |
1 MFSLKALLPL ALLLVSANQV AAKVHKAKIY KHELSDEMKE VTFEQHLAHL GQKYLTQFEK 60
61 ANPEVVFSRE HPFF
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| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.735 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.766 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.847 | a.64.1 | Saposin |
| View | Download | 0.811 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.887 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.727 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.715 | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.678 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.676 | a.2.7 | tRNA-binding arm |
| View | Download | 0.658 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.638 | a.30.1 | ROP protein |
| View | Download | 0.611 | a.2.7 | tRNA-binding arm |
| View | Download | 0.594 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.561 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.462 | a.2.3 | Chaperone J-domain |
| View | Download | 0.455 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.444 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.440 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.412 | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.396 | a.4.1 | Homeodomain-like |
| View | Download | 0.375 | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| View | Download | 0.372 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.363 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.361 | a.46.1 | Methionine synthase domain |
| View | Download | 0.355 | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.354 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.352 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.350 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.343 | d.29.1 | Ribosomal protein L31e |
| View | Download | 0.340 | a.65.1 | Annexin |
| View | Download | 0.336 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.332 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.319 | a.4.1 | Homeodomain-like |
| View | Download | 0.309 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.308 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.299 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.295 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.294 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.294 | a.5.2 | UBA-like |
| View | Download | 0.290 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.286 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.285 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.283 | a.64.1 | Saposin |
| View | Download | 0.281 | a.4.1 | Homeodomain-like |
| View | Download | 0.281 | d.10.1 | DNA-binding domain |
| View | Download | 0.280 | a.21.1 | HMG-box |
| View | Download | 0.279 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.276 | d.15.2 | CAD & PB1 domains |
| View | Download | 0.275 | a.7.1 | Spectrin repeat |
| View | Download | 0.273 | a.112.1 | Description not found. |
| View | Download | 0.269 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.268 | a.22.1 | Histone-fold |
| View | Download | 0.267 | d.39.1 | Dynein light chain 8 (DLC8) |
| View | Download | 0.263 | f.17.2 | Cytochrome c oxidase subunit II-like, transmembrane region |
| View | Download | 0.262 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.261 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.261 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.254 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.251 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.249 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.245 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.244 | a.126.1 | Serum albumin-like |
| View | Download | 0.242 | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.240 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.238 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.234 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.231 | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.230 | a.2.5 | Prefoldin |
| View | Download | 0.228 | a.4.1 | Homeodomain-like |
| View | Download | 0.225 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.222 | f.16.1 | Gated mechanosensitive channel |
| View | Download | 0.221 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.220 | a.2.3 | Chaperone J-domain |
| View | Download | 0.218 | a.39.1 | EF-hand |
| View | Download | 0.217 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.211 | f.28.1 | Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.208 | a.101.1 | Uteroglobin-like |
| View | Download | 0.208 | a.1.1 | Globin-like |
| View | Download | 0.206 | a.4.1 | Homeodomain-like |
| View | Download | 0.203 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.203 | a.7.7 | BAG domain |
| View | Download | 0.200 | a.3.1 | Cytochrome c |
| Term | Confidence | Notes |
| aspartic-type endopeptidase activity | 7.9145950161796 | bayes_pls_golite062009 |
| aspartic-type peptidase activity | 7.9145950161796 | bayes_pls_golite062009 |
| peptidase activity | 5.78181196721293 | bayes_pls_golite062009 |
| endopeptidase activity | 5.4888481808613 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 5.39972232367526 | bayes_pls_golite062009 |
| hydrolase activity | 4.34796304893506 | bayes_pls_golite062009 |
| catalytic activity | 1.54514410489082 | bayes_pls_golite062009 |
| binding | 1.10054369202721 | bayes_pls_golite062009 |
| receptor binding | 0.561225023505917 | bayes_pls_golite062009 |
| protein binding | 0.193907750061394 | bayes_pls_golite062009 |
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Region A: Residues: [75-91] |
1 11 21 31 41 51
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1 TEGGHDVPLT NYLNAQY
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Region B: Residues: [225-405] |
1 11 21 31 41 51
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1 EKRFAFYLGD TSKDTENGGE ATFGGIDESK FKGDITWLPV RRKAYWEVKF EGIGLGDEYA 60
61 ELESHGAAID TGTSLITLPS GLAEMINAEI GAKKGWTGQY TLDCNTRDNL PDLIFNFNGY 120
121 NFTIGPYDYT LEVSGSCISA ITPMDFPEPV GPLAIVGDAF LRKYYSIYDL GNNAVGLAKA 180
181 I
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| Detection Method: | |
| Confidence: | 10123.0 |
| Match: | 1dp5A_ |
| Description: | Acid protease |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [92-224] |
1 11 21 31 41 51
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1 YTDITLGTPP QNFKVILDTG SSNLWVPSNE CGSLACFLHS KYDHEASSSY KANGTEFAIQ 60
61 YGTGSLEGYI SQDTLSIGDL TIPKQDFAEA TSEPGLTFAF GKFDGILGLG YDTISVDKVV 120
121 PPFYNAIQQD LLD
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| Detection Method: | |
| Confidence: | 10123.0 |
| Match: | 1dp5A_ |
| Description: | Acid protease |
| Matching Structure (courtesy of the PDB): |
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