| Protein: | GDE1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1223 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GDE1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1223] | [1..1223] |
|
|
0.0 | [49..875] | [4..814] |
|
|
0.0 | [72..911] | [20..835] |
|
|
0.0 | [31..910] | [2..859] |
|
Region A: Residues: [1-202] |
1 11 21 31 41 51
| | | | | |
1 MKFGKTFANH RIPEWSSQYV GYKSLKKMIK EITRLQEDIY RAHNKNSYDE GRPPTKMRDS 60
61 SNSAQNYLDS PKIQKLLASF FFAVDRDIEK VDTFYNSQYA EYKKRFERLL SSNQFNEIKS 120
121 TLVVDANKED AVAQTLLTKD TREMNMLLKG TSQASRLSYH KDDLIEIQSI LAELRKQFRN 180
181 LKWYAELNKR AFGKILKKLD KK
|
| Detection Method: |  |
| Confidence: | 50.102373 |
| Match: | PF03105 |
| Description: | SPX domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [203-262] |
1 11 21 31 41 51
| | | | | |
1 VGTNQQMSTM KTRILPLQFA NDSLITKDLS LLKTIWEQVT FRINSYERVM RSTSPNANAN 60
61
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.520 | a.4.1 | Homeodomain-like |
| View | Download | 0.570 | a.5.2 | UBA-like |
| View | Download | 0.345 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.583 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.342 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.338 | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.321 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.314 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.311 | a.101.1 | Uteroglobin-like |
| View | Download | 0.308 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.307 | a.4.1 | Homeodomain-like |
| View | Download | 0.294 | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.285 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.279 | a.4.1 | Homeodomain-like |
| View | Download | 0.276 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.271 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.267 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.258 | a.39.1 | EF-hand |
| View | Download | 0.255 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.239 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.232 | a.112.1 | Description not found. |
| View | Download | 0.232 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.210 | a.4.10 | N-terminal Zn binding domain of HIV integrase |
| View | Download | 0.208 | a.74.1 | Cyclin-like |
| View | Download | 0.208 | a.39.1 | EF-hand |
| View | Download | 0.204 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
|
Region A: Residues: [263-366] |
1 11 21 31 41 51
| | | | | |
1 DNTEFFKIIC VFIEEDDSKG LIRELTNLYS ELSLIPTRIM ISVLNKAALS KSLACIDAIL 60
61 KVIPSLNDSE DINRRNFFHH HIIAIGKLIR KQEILSRKKK SQPS
|
| Detection Method: | |
| Confidence: | 177.045757 |
| Match: | 1n11A_ |
| Description: | Ankyrin-R |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| structural molecule activity | 2.22255916855045 | bayes_pls_golite062009 |
| binding | 1.62593430784178 | bayes_pls_golite062009 |
| protein binding | 1.39636607384619 | bayes_pls_golite062009 |
| calcium-independent phospholipase A2 activity | 0.621306773219824 | bayes_pls_golite062009 |
|
Region A: Residues: [367-499] |
1 11 21 31 41 51
| | | | | |
1 KYTNSEGEIV TDLRTLHTTL SAPAESDSIT EEEKSSACTL SYILEELPIH LRPCLFQHDN 60
61 YKRTPLHYSC QYGLSEVTKL IIKLMKEWNI WNEIPIDDVS AFGDAESLTP LHLCVLGAHP 120
121 KTTEVLLQSL DPN
|
|
Region B: Residues: [516-527] |
1 11 21 31 41 51
| | | | | |
1 NYPLLHVLLS SK
|
| Detection Method: | |
| Confidence: | 177.045757 |
| Match: | 1n11A_ |
| Description: | Ankyrin-R |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [500-515] |
1 11 21 31 41 51
| | | | | |
1 VKLKSSSLLH LATEWN
|
|
Region B: Residues: [528-680] |
1 11 21 31 41 51
| | | | | |
1 RFDINYQDNE LHETPLYLAC RLNFFEAAVC LLYNGADLEI REKLFGWTAI FVAAAEGFTD 60
61 IVKLLIANNA NFDIEDEGGW TPMEHAVLRG HLHIADMVQI RDELVTHPHS QLNSGSEEKE 120
121 PLNEISAGEL NERNENGNGG NKGSLGKLAG PIK
|
| Detection Method: | |
| Confidence: | 177.045757 |
| Match: | 1n11A_ |
| Description: | Ankyrin-R |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [681-748] |
1 11 21 31 41 51
| | | | | |
1 SYGHRFLDNN ESLILITLGS NDTRNKSPSI SLSSEALAKV IGLETDCALS LVISCNDSID 60
61 KSSVILDL
|
| Detection Method: | |
| Confidence: | 9.0 |
| Match: | 1sw6A_ |
| Description: | Swi6 ankyrin-repeat fragment |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| glycerophosphodiester phosphodiesterase activity | 4.27697417361287 | bayes_pls_golite062009 |
| phosphoric diester hydrolase activity | 3.6633363681844 | bayes_pls_golite062009 |
| phospholipase activity | 3.3535603060637 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.89024275707278 | bayes_pls_golite062009 |
| phospholipase C activity | 2.81479108775786 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol phosphodiesterase activity | 2.13368269358874 | bayes_pls_golite062009 |
| phosphoinositide phospholipase C activity | 2.13368269358874 | bayes_pls_golite062009 |
| hydrolase activity | 1.64631444998344 | bayes_pls_golite062009 |
| lipase activity | 1.30779031242608 | bayes_pls_golite062009 |
| phosphatidylglycerol phospholipase C activity | 1.28645679518658 | bayes_pls_golite062009 |
| catalytic activity | 1.22328099675039 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.21202479488854 | bayes_pls_golite062009 |
| binding | 0.701659508863933 | bayes_pls_golite062009 |
| protein binding | 0.137516733383577 | bayes_pls_golite062009 |
|
Region A: Residues: [749-857] |
1 11 21 31 41 51
| | | | | |
1 PLDDNVDAVD FKVPFKVDYS HTLYFDIVPT YGTRSLETHN RIDCQKNNNN YVMARGVSML 60
61 NKSYSSVGVN RSILNGSVTV PIIANHTLEI LGTLKFEYII ITPFEHPQL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.240 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.341 | b.61.3 | D-aminopeptidase, middle and C-terminal domains |
| View | Download | 0.391 | b.61.4 | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
| View | Download | 0.275 | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.240 | b.60.1 | Lipocalins |
| View | Download | 0.236 | b.1.1 | Immunoglobulin |
| View | Download | 0.230 | d.110.1 | Profilin (actin-binding protein) |
| View | Download | 0.227 | b.1.1 | Immunoglobulin |
| View | Download | 0.227 | b.71.1 | Glycosyl hydrolase domain |
| View | Download | 0.220 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.211 | b.55.1 | PH domain-like |
| View | Download | 0.200 | d.226.1 | GIY-YIG endonuclease |
|
Region A: Residues: [858-1039] |
1 11 21 31 41 51
| | | | | |
1 PLERTETYWK SLVSTRVIGH RGLGKNNPNK SLQIGENTVE SFIMAASLGA SYVEFDVQLT 60
61 KDNVPVVYHD FLVAETGVDI PMHELTLEQF LDLNNADKEH IQRGAGHSPH HVNGADTALQ 120
121 KYRGRSVDDS DVSTLRRAWD LHDNDPNGKS NNAHWSDNRM RLTKTFKKNN FKGNARGHSI 180
181 AS
|
| Detection Method: | |
| Confidence: | 47.69897 |
| Match: | 1o1zA_ |
| Description: | Hypothetical protein TM1621 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1040-1223] |
1 11 21 31 41 51
| | | | | |
1 SFVTLKELFK KIPANVGFNI ECKFPMLDEA EEEELGQIMM EMNHWVDTVL KVVFDNANGR 60
61 DIIFSSFHPD ICIMLSLKQP VIPILFLTEG GSEQMADLRA SSLQNGIRFA KKWNLLGIVS 120
121 AAAPILKAPR LVQVVKSNGL VCVTYGVDNN DPENASIQIE AGVDAVIVDS VLAIRRGLTK 180
181 KNEK
|
| Detection Method: | |
| Confidence: | 14.130768 |
| Match: | PF03009 |
| Description: | Glycerophosphoryl diester phosphodiesterase family |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
