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View Structure Prediction Details

Protein: MSB1
Organism: Saccharomyces cerevisiae
Length: 1137 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSB1.

Description E-value Query
Range
Subject
Range
MSB1 - Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway...
MSB1_YEAST - Morphogenesis-related protein MSB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSB1 ...
0.0 [1..1137] [1..1137]

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Predicted Domain #1
Region A:
Residues: [1-1137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDMAKPLPT PPTAEIRKSR SNSPKKAQKT NLSPNKNQNN EKNVPRSNGR TKNEHNSMDD  60
   61 EEFEFFHQFS REKVKGVIHV ITAELKEKGP DVEFLMIPFR PEQTNDKLLT LLNQLFPLGN 120
  121 GQPVNEKKQL RIVSKADVWT LFQCLKYIWC RLPNSEIIGW KSYLEFKFRE EDKKFPRKSF 180
  181 LEIMPQCLAS PNHASIVYDF FDLIISISSN SRVNKMSARK ISKMCAIWAF SKQIPNSDIQ 240
  241 DYDFESAAMK SFAPNNSIQD GLDQWIPASD AMFHLLLAFL RSFVPQDLES AKLPRTLKSL 300
  301 LFNNQYPPRK STAYTSETIL TIPLVTLKTD VFSRKPWQLL ERCNDLLDFS DHDAFEARED 360
  361 YALLKSLFRK KNTVEGISRK MSQESRRLMK AMSTKHSTFQ PGWAPRECIE NISHLKECIE 420
  421 VKRLDIDDYF IWTWLSSLSF EQTSEKKKIF GRSIILEFEF DGFKKWVVFQ ECDITLDYNK 480
  481 KGQLKKKTSA QSPTTEKELP PDDFELEDPP LSKSPTLSQT YKKFQAEVPQ QSTVRRDSAP 540
  541 DNQGIYHTVI SKNALTKNKH NVNLHSFEHK ISKWNPLNNL RKKSGSNSSS SSFEEKSKDA 600
  601 PIREEYHTNK NHKSKKEERV LSQFSTLNPD EYQLPVIETG SSNFKIEIPE LMYEHDDDDS 660
  661 DKLKNSQKRA TDSAIEELNG MVEEMMINEP DDVKISITEA ETFESLTKFD QYKPSNITDD 720
  721 DLQSSHSSAV HSLKLSTNTN DSCADSSKYT ADRKLAEPRK ISEESKVNDD SSSYYSPNIN 780
  781 NLPASRMPSQ PTYSNSDSKK AFTNESRLNV LQGAVSPSQQ VTPKPYKNAP GDCVSPVQQK 840
  841 YYQNDRRNEM SPASAPVPPS AYSPARSPQF STNSAGFKQN TINVPVGYND PAHVLANQPH 900
  901 MTYRDQHNYP SHQQKQRPFQ NNIVPPELKS RNQRADASPI PQHMVPVKQG VPNLPSNVPL 960
  961 YQQMERMNPN HQHPVNTYKV TQPPYHNNTT NAYGNSRAGN AHMLDGKWSN NPPQMVPKGV1020
 1021 RPNQYPQQHV NRYSPQAQPV VPAEYYNGPP PMRAPPMMSH MVPAQEPIRY TAGANRRSFP1080
 1081 QGMQQNAYSV PAQPMGAVNS EFYLPEAPQG NKLHGNINKR QERKKLYDNI RSGNFGI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
GTPase regulator activity 4.71716966080106 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 4.69832265514374 bayes_pls_golite062009
small GTPase regulator activity 4.40136729916219 bayes_pls_golite062009
GTPase activator activity 4.21856723160728 bayes_pls_golite062009
Ras GTPase activator activity 4.1605878971879 bayes_pls_golite062009
enzyme regulator activity 4.0832203055885 bayes_pls_golite062009
Rho GTPase activator activity 3.97925606841162 bayes_pls_golite062009
enzyme activator activity 3.75634032603914 bayes_pls_golite062009
Rac GTPase activator activity 2.74441072565017 bayes_pls_golite062009
binding 1.81232559960956 bayes_pls_golite062009
protein binding 1.14158567179227 bayes_pls_golite062009
GTPase binding 0.29835601475567 bayes_pls_golite062009
small GTPase binding 0.129342092181805 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [309-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKSTAYTSET ILTIPLVTLK TDVFSRKPWQ LLERCNDLLD FSDHDAFEAR EDYALLKSLF  60
   61 RKKNTVEGIS RKMSQESRRL MKAMSTKHST FQPGWAPREC IENISHLKEC IEVKRLDIDD 120
  121 YFIWTWLSSL SFEQTSEKKK IFGRSIILEF EFDGFKKWVV FQECDITLDY NKKGQLKKKT 180
  181 SAQSPTTEKE LPPDDFELED PPLSKSPTLS QTYKKFQAEV PQQSTVRRDS APDNQGIYHT 240
  241 VISKNALTKN KHNVNLHSFE HKISKWNPLN NLRKKSGSNS 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [589-771]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSFEEKSK DAPIREEYHT NKNHKSKKEE RVLSQFSTLN PDEYQLPVIE TGSSNFKIEI  60
   61 PELMYEHDDD DSDKLKNSQK RATDSAIEEL NGMVEEMMIN EPDDVKISIT EAETFESLTK 120
  121 FDQYKPSNIT DDDLQSSHSS AVHSLKLSTN TNDSCADSSK YTADRKLAEP RKISEESKVN 180
  181 DDS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [772-929]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSYYSPNINN LPASRMPSQP TYSNSDSKKA FTNESRLNVL QGAVSPSQQV TPKPYKNAPG  60
   61 DCVSPVQQKY YQNDRRNEMS PASAPVPPSA YSPARSPQFS TNSAGFKQNT INVPVGYNDP 120
  121 AHVLANQPHM TYRDQHNYPS HQQKQRPFQN NIVPPELK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [930-1137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRNQRADASP IPQHMVPVKQ GVPNLPSNVP LYQQMERMNP NHQHPVNTYK VTQPPYHNNT  60
   61 TNAYGNSRAG NAHMLDGKWS NNPPQMVPKG VRPNQYPQQH VNRYSPQAQP VVPAEYYNGP 120
  121 PPMRAPPMMS HMVPAQEPIR YTAGANRRSF PQGMQQNAYS VPAQPMGAVN SEFYLPEAPQ 180
  181 GNKLHGNINK RQERKKLYDN IRSGNFGI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle