YRC Public Data Repository - Protein Structure Prediction

Protein:	NUP1
Organism:	Saccharomyces cerevisiae
Length:	1076 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP1.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	8.0E-95	[11..1061]	[2..1048]
MUC1 - mucin 1, cell surface associated	3.0E-88	[18..1041]	[1..1028]
SPBPJ4664.02 - glycoprotein YHU2_SCHPO - Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 OS=Schizosaccharomyces pombe (str...	2.0E-86	[4..1054]	[1363..2416]
NUP1_YEAST - Nucleoporin NUP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP1 PE=1 SV=1 NUP1 - Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possibl...	4.0E-67	[1..1076]	[1..1076]
gi\|15828996 - gi\|15828996\|ref\|NP_326356.1\| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP] gi\|14089939, gi\|... - pir\|\|E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi\|14089...	3.0E-63	[231..1052]	[12..831]

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Predicted Domain #1

Region A:
Residues: [1-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNTSSVMS SPRVEKRSFS STLKSFFTNP NKKRPSSKKV FSSNLSYANH LEESDVEDTL  60
   61 HVNKRKRVSG TSQHSDSLTQ NNNNAPIIIY GTENTERPPL LPILPIQRLR LLREKQRVRN 120
  121 MRELGLIQST EFPSITSSVI LGSQSKSDEG GSYLCTSSTP SPIKNGSCTR QLAGKSGEDT 180
  181 NVGLPILKSL KNRSNRKRFH SQSKGTVWSA NFEYDLSEYD AIQKKDNKDK EGNAGGDQKT 240
  241 SENRNNIKSS ISNGNLATGP NLTSEIEDLR ADINSN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [277-1076]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLSNPQKNLL LKGPASTVAK TAPIQESFVP NSERSGTPTL KKNIEPKKDK ESIVLPTVGF  60
   61 DFIKDNETPS KKTSPKATSS AGAVFKSSVE MGKTDKSTKT AEAPTLSFNF SQKANKTKAV 120
  121 DNTVPSTTLF NFGGKSDTVT SASQPFKFGK TSEKSENHTE SDAPPKSTAP IFSFGKQEEN 180
  181 GDEGDDENEP KRKRRLPVSE DTNTKPLFDF GKTGDQKETK KGESEKDASG KPSFVFGASD 240
  241 KQAEGTPLFT FGKKADVTSN IDSSAQFTFG KAATAKETHT KPSETPATIV KKPTFTFGQS 300
  301 TSENKISEGS AKPTFSFSKS EEERKSSPIS NEAAKPSFSF PGKPVDVQAP TDDKTLKPTF 360
  361 SFTEPAQKDS SVVSEPKKPS FTFASSKTSQ PKPLFSFGKS DAAKEPPGSN TSFSFTKPPA 420
  421 NETDKRPTPP SFTFGGSTTN NTTTTSTKPS FSFGAPESMK STASTAAANT EKLSNGFSFT 480
  481 KFNHNKEKSN SPTSFFDGSA SSTPIPVLGK PTDATGNTTS KSAFSFGTAN TNGTNASANS 540
  541 TSFSFNAPAT GNGTTTTSNT SGTNIAGTFN VGKPDQSIAS GNTNGAGSAF GFSSSGTAAT 600
  601 GAASNQSSFN FGNNGAGGLN PFTSATSSTN ANAGLFNKPP STNAQNVNVP SAFNFTGNNS 660
  661 TPGGGSVFNM NGNTNANTVF AGSNNQPHQS QTPSFNTNSS FTPSTVPNIN FSGLNGGITN 720
  721 TATNALRPSD IFGANAASGS NSNVTNPSSI FGGAGGVPTT SFGQPQSAPN QMGMGTNNGM 780
  781 SMGGGVMANR KIARMRHSKR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [389-632]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KANKTKAVDN TVPSTTLFNF GGKSDTVTSA SQPFKFGKTS EKSENHTESD APPKSTAPIF  60
   61 SFGKQEENGD EGDDENEPKR KRRLPVSEDT NTKPLFDFGK TGDQKETKKG ESEKDASGKP 120
  121 SFVFGASDKQ AEGTPLFTFG KKADVTSNID SSAQFTFGKA ATAKETHTKP SETPATIVKK 180
  181 PTFTFGQSTS ENKISEGSAK PTFSFSKSEE ERKSSPISNE AAKPSFSFPG KPVDVQAPTD 240
  241 DKTL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [633-746]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPTFSFTEPA QKDSSVVSEP KKPSFTFASS KTSQPKPLFS FGKSDAAKEP PGSNTSFSFT  60
   61 KPPANETDKR PTPPSFTFGG STTNNTTTTS TKPSFSFGAP ESMKSTASTA AANT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [747-892]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKLSNGFSFT KFNHNKEKSN SPTSFFDGSA SSTPIPVLGK PTDATGNTTS KSAFSFGTAN  60
   61 TNGTNASANS TSFSFNAPAT GNGTTTTSNT SGTNIAGTFN VGKPDQSIAS GNTNGAGSAF 120
  121 GFSSSGTAAT GAASNQSSFN FGNNGA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [893-1076]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGLNPFTSAT SSTNANAGLF NKPPSTNAQN VNVPSAFNFT GNNSTPGGGS VFNMNGNTNA  60
   61 NTVFAGSNNQ PHQSQTPSFN TNSSFTPSTV PNINFSGLNG GITNTATNAL RPSDIFGANA 120
  121 ASGSNSNVTN PSSIFGGAGG VPTTSFGQPQ SAPNQMGMGT NNGMSMGGGV MANRKIARMR 180
  181 HSKR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits