| Protein: | CMR2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1648 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CMR2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1648] | [1..1648] |
|
|
0.0 | [4..982] | [1396..2246] |
|
|
0.0 | [4..896] | [1480..2233] |
|
|
0.0 | [4..982] | [294..1128] |
|
|
0.0 | [4..1007] | [1333..2177] |
|
|
0.0 | [4..999] | [1342..2223] |
|
Region A: Residues: [1-61] |
1 11 21 31 41 51
| | | | | |
1 MDFSIPPTLP LDLQSRLNEL IQDYKDENLT RKGYETKRKQ LLDKFEISQM RPYTPLRSPN 60
61 S
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.695 | N/A | N/A | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.564 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.536 | N/A | N/A | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.509 | N/A | N/A | d.39.1 | Dynein light chain 8 (DLC8) |
| View | Download | 0.506 | N/A | N/A | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.505 | N/A | N/A | d.58.38 | Urease metallochaperone UreE, C-terminal domain |
| View | Download | 0.472 | N/A | N/A | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.459 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.458 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.445 | N/A | N/A | d.58.48 | MTH1187-like |
| View | Download | 0.441 | N/A | N/A | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.429 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.428 | N/A | N/A | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.416 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.411 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.406 | N/A | N/A | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.397 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.390 | N/A | N/A | d.58.5 | GlnB-like |
| View | Download | 0.385 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.382 | N/A | N/A | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.378 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.370 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.366 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.355 | N/A | N/A | a.112.1 | Description not found. |
| View | Download | 0.348 | N/A | N/A | d.15.7 | Immunoglobulin-binding domains |
| View | Download | 0.335 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.334 | N/A | N/A | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.327 | N/A | N/A | a.30.1 | ROP protein |
| View | Download | 0.321 | N/A | N/A | d.58.5 | GlnB-like |
| View | Download | 0.304 | N/A | N/A | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.297 | N/A | N/A | d.52.5 | Probable GTPase Der, C-terminal domain |
| View | Download | 0.296 | N/A | N/A | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.294 | N/A | N/A | d.64.1 | eIF1-like |
| View | Download | 0.291 | N/A | N/A | g.63.1 | Mollusk pheromone |
| View | Download | 0.291 | N/A | N/A | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.288 | N/A | N/A | d.58.48 | MTH1187-like |
| View | Download | 0.288 | N/A | N/A | a.79.1 | Antitermination factor NusB |
| View | Download | 0.287 | N/A | N/A | d.58.5 | GlnB-like |
| View | Download | 0.286 | N/A | N/A | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.286 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.279 | N/A | N/A | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.279 | N/A | N/A | a.55.1 | IHF-like DNA-binding proteins |
| View | Download | 0.273 | N/A | N/A | d.58.25 | Killer toxin KP6 alpha-subunit |
| View | Download | 0.269 | N/A | N/A | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.268 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.266 | N/A | N/A | d.58.23 | Probable ACP-binding domain of malonyl-CoA ACP transacylase |
| View | Download | 0.265 | N/A | N/A | d.230.3 | Amyloid beta a4 protein copper binding domain (domain 2) |
| View | Download | 0.264 | N/A | N/A | d.47.1 | Ribosomal protein L11, N-terminal domain |
| View | Download | 0.264 | N/A | N/A | d.58.49 | YajQ-like |
| View | Download | 0.255 | N/A | N/A | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.252 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.251 | N/A | N/A | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.251 | N/A | N/A | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.247 | N/A | N/A | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.237 | N/A | N/A | a.159.2 | FF domain |
| View | Download | 0.237 | N/A | N/A | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.234 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.233 | N/A | N/A | g.13.1 | Crambin-like |
| View | Download | 0.231 | N/A | N/A | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.231 | N/A | N/A | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.226 | N/A | N/A | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.226 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.225 | N/A | N/A | d.58.49 | YajQ-like |
| View | Download | 0.217 | N/A | N/A | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.215 | N/A | N/A | g.2.2 | Neurotoxin B-IV |
| View | Download | 0.214 | N/A | N/A | a.17.1 | p8-MTCP1 |
| View | Download | 0.213 | N/A | N/A | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.209 | N/A | N/A | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
|
Region A: Residues: [62-139] |
1 11 21 31 41 51
| | | | | |
1 RKSKHLHRRN TSLASSITSL PNSIDRRHSI YRVTTINSTS ANNTPRRRSK RYTASLQSSL 60
61 PGSSDENGSV KDAVYNPM
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.524 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.492 | d.212.1 | TolA/TonB C-terminal domain |
| View | Download | 0.357 | a.39.1 | EF-hand |
| View | Download | 0.354 | c.52.2 | tRNA splicing endonuclease, C-terminal domain |
| View | Download | 0.338 | d.52.5 | Probable GTPase Der, C-terminal domain |
| View | Download | 0.315 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.297 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.284 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.265 | d.58.49 | YajQ-like |
| View | Download | 0.255 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.248 | a.64.1 | Saposin |
| View | Download | 0.240 | a.2.7 | tRNA-binding arm |
| View | Download | 0.232 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.222 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.213 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.203 | a.4.1 | Homeodomain-like |
| Term | Confidence | Notes |
| catalytic activity | 1.06902368506559 | bayes_pls_golite062009 |
| ligase activity | 0.763554068965808 | bayes_pls_golite062009 |
| ligase activity, forming carbon-sulfur bonds | 0.619465698462354 | bayes_pls_golite062009 |
|
Region A: Residues: [140-154] |
1 11 21 31 41 51
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1 IPLLPRHTGA ENTSS
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Region B: Residues: [425-701] |
1 11 21 31 41 51
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1 DSSILQRPGG YENIIDKFRA DILLNDQLQL KQVVINYLEN PESAFSKKHK IDFSCIKSCL 60
61 TSCTTIDTDV SEMVVHKWLK NLGCIDAPFC YSPMLTLLDF GGIFISIRDQ LGNLENFPIH 120
121 NSKLRLQNEL FINREKLKLN EVECSITAMI NSSSSFKDYL KLETFGFPIP DITLCVVNPD 180
181 TNTLVQDLTV GEIWISSNHI TDEFYQMDKV NEFVFKAKLN YSEMFSWAKY EMPTNEKSQA 240
241 VTEQLDTILN ICPANTYFMR TKLMGFVHNG KIYVLSL
|
| Detection Method: | |
| Confidence: | 131.0 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| substrate-specific transporter activity | 0.205687421762746 | bayes_pls_golite062009 |
| transporter activity | 0.164841961310903 | bayes_pls_golite062009 |
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Region A: Residues: [155-196] |
1 11 21 31 41 51
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1 GDSAMTDSLP LILRGRFEHY DGQTAMISIN SKGKETFITW DK
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Region B: Residues: [337-424] |
1 11 21 31 41 51
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1 TPLGRLSGVV MKHNILINQF ETMTKILNSR SMPHWKQKSQ SIRKPFHKKI MATNSRFVIL 60
61 NSLDPTRSTG LIMGVLFNLF TGNLMISI
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|
Region C: Residues: [702-832] |
1 11 21 31 41 51
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1 IEDMFLQNRL IRLPNWAHTS NLLYAKKGNQ SAQPKGNTGA ESTKAIDISS LSGETSSGYK 60
61 RVVESHYLQQ ITETVVRTVN TVFEVAAFEL QHHKEEHFLV MVVESSLAKT EEESKNGETT 120
121 DTTLMKFAET Q
|
| Detection Method: | |
| Confidence: | 131.0 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [197-336] |
1 11 21 31 41 51
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1 LYLKAERVAH ELNKSHLYKM DKILLWYNKN DVIEFTIALL GCFISGMAAV PVSFETYSLR 60
61 EILEIIKVTN SKFVLISNAC HRQLDNLYSS SNHSKVKLVK NDVFQQIKFV KTDDLGTYTK 120
121 AKKTSPTFDI PNISYIEFTR
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| Detection Method: | |
| Confidence: | 131.0 |
| Match: | 1amuA_ |
| Description: | Phenylalanine activating domain of gramicidin synthetase 1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [833-910] |
1 11 21 31 41 51
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1 RNKLETKMND LTDQIFRILW IFHKIQPMCI LVVPRDTLPR RYCSLELANS TVEKKFLNND 60
61 LSAQFVKFQF DNVILDFL
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| Detection Method: | |
| Confidence: | 13.045757 |
| Match: | 1dnyA_ |
| Description: | Peptidyl carrier protein (PCP), thioester domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [911-973] |
1 11 21 31 41 51
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1 PHSAYYNESI LSEHLSKLRK MALQEEYAMI EPAYRNGGPV KPKLALQCSG VDYRDESVDT 60
61 RSH
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.837 | a.65.1 | Annexin |
| View | Download | 0.593 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.567 | a.5.1 | DNA helicase RuvA subunit, C-terminal domain |
| View | Download | 0.509 | a.4.1 | Homeodomain-like |
| View | Download | 0.496 | a.17.1 | p8-MTCP1 |
| View | Download | 0.468 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.462 | a.4.1 | Homeodomain-like |
| View | Download | 0.451 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.437 | a.4.1 | Homeodomain-like |
| View | Download | 0.386 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.385 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.383 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.382 | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.374 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.336 | a.4.1 | Homeodomain-like |
| View | Download | 0.312 | a.74.1 | Cyclin-like |
| View | Download | 0.310 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.296 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.292 | a.4.1 | Homeodomain-like |
| View | Download | 0.277 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.271 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.271 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.267 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.263 | a.5.2 | UBA-like |
| View | Download | 0.257 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.256 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.253 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.251 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.249 | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.246 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.242 | a.4.1 | Homeodomain-like |
| View | Download | 0.241 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.235 | g.1.1 | Insulin-like |
| View | Download | 0.223 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.208 | a.112.1 | Description not found. |
| View | Download | 0.206 | a.77.1 | DEATH domain |
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Region A: Residues: [974-1009] |
1 11 21 31 41 51
| | | | | |
1 TKLTDFKSIL EILEWRISNY GNETAFSDGT NTNLVN
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Region B: Residues: [1023-1175] |
1 11 21 31 41 51
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1 SWASFGKIVA GFLKKIVGSK IPLKHGDPII IMCENSVEYV AMIMACLYCN LLVIPLPSVK 60
61 ESVIEEDLKG LVNIIQSYKV KRVFVDAKLH SLLNDNNVVN KCFKKYKSLI PKITVFSKVK 120
121 TKNALTVSMF KNVLKQKFGA KPGTRIGMTP CVV
|
| Detection Method: | |
| Confidence: | 79.09691 |
| Match: | 1ba3__ |
| Description: | Luciferase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1010-1022] |
1 11 21 31 41 51
| | | | | |
1 SSASNDNNVH KKV
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Region B: Residues: [1176-1510] |
1 11 21 31 41 51
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1 WVNTEYDVTS NIHVTMTHSS LLNASKIVKE TLQLRNNSPL FSICSHTSGL GFMFSCLLGI 60
61 YTGASTCLFS LTDVLTDPKE FLIGLQNLNV KDLYLKLETL YALLDRASSL IEGFKNKKEN 120
121 INSAKNNTSG SLREDVFKGV RNIMIPFPNR PRIYTIENIL KRYSTISLSC TQISYVYQHH 180
181 FNPLISLRSY LDIPPVDLYL DPFSLREGII REVNPNDVSA GNYIKIQDSG VVPVCTDVSV 240
241 VNPETLLPCV DGEFGEIWCC SEANAFDYFV CNSSKNKLYK DPFITEQFKS KMKSEVNNTL 300
301 SYLRTGDLGF IKNVSCTNSQ GEVVNLNLLF VLGSI
|
| Detection Method: | |
| Confidence: | 79.09691 |
| Match: | 1ba3__ |
| Description: | Luciferase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1511-1648] |
1 11 21 31 41 51
| | | | | |
1 HESIEILGLT HFVSDLERTV KDVHSDIGSC LIAKAGGLLV CLIRCKERHN PILGNLTTLI 60
61 VSELLNKHGV ILDLCTFVRT KGISPKNSSM IMEVWAKNRA SIMQAWFDQK IQIEAQFGIN 120
121 YGENISIYLL SDYEKDNI
|
| Detection Method: | |
| Confidence: | 79.09691 |
| Match: | 1ba3__ |
| Description: | Luciferase |
| Matching Structure (courtesy of the PDB): |
|
