YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: TGL5
Organism: Saccharomyces cerevisiae
Length: 749 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TGL5.

Description E-value Query
Range
Subject
Range
gi|190407416 - gi|190407416|gb|EDV10683.1| hypothetical protein SCRG_01481 [Saccharomyces cerevisiae RM11-1a]
TGL5 - Bifunction enzyme with triacylglycerol lipase and lysophosphatidic acid acyltransferase activity; in...
TGL5_YEAST - Lipase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TGL5 PE=1 SV=1
0.0 [1..749] [1..749]
gi|20804680, gi|... - gi|50902030|ref|XP_463448.1| P0512C01.22 [Oryza sativa (japonica cultivar-group)], gi|20804680|dbj|B...
0.0 [52..595] [106..632]
SDP1_ARATH - Triacylglycerol lipase SDP1 OS=Arabidopsis thaliana GN=SDP1 PE=1 SV=1
0.0 [52..596] [105..636]
YCKG_SCHPO - Uncharacterized protein C1450.16c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC1450...
SPCC1450.16c - triacylglycerol lipase
0.0 [28..527] [24..503]
gi|4539677, gi|2... - gi|4539677|gb|AAD22170.1|AF061282_24 patatin-like protein [Sorghum bicolor], gi|242071683|ref|XP_002...
3.0E-87 [175..566] [18..403]

Back

Predicted Domain #1
Region A:
Residues: [1-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNTLPVTEF LLSKYYELSN TPATDSSSLF KWLYHKTLSR KQLLISDLSS QKKHAISYDQ  60
   61 WNDIASRLDD LTGLSEWKTI DESSLYNYKL LQDLTIRMRH LRTTHDYHRL LYLIRTKWVR 120
  121 NLGNMNNVNL YRHSHTGTKQ IIHDYLEESQ AVLTALIHQS NMNDHYLLGI LQQTRRNIGR 180
  181 TALVLSGGST FGLFHIGVLA ALFESDLMPK VISGSSAGAI VASIFCVHTT QEIPSLLTNV 240
  241 LNMEFNIFND DNSKSPNENL LIKISRFCQN GTWFNNQPLI NTMLSFLGNL TFREAYNKTG 300
  301 KILNITVSPA SIYE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.19
Match: 1itwA
Description: Monomeric isocitrate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [315-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPKLLNNLTA PNVLIWSAVC ASCSLPGVFP STPLFEKDPH TGKIKEWGAT NLHLSNMKFM  60
   61 DGSVDNDMPI SRLSEMFNVD HIIACQVNIH VFPLLKFSNT CVG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [418-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEIEKEITAR FRNQVTKIFK FFSDETIHFL DILKELEFHP YLMTKLKHLF LQQYSGNVTI  60
   61 LPDLSMVGQF HEVLKNPSQL FLLHQTTLGA RATWPKISMI QNNCGQEFAL DKAITFLKEK 120
  121 IIISSSIKNP LQFYQPRFSE QIKSLSIMDA DLPGVDLEES SSNSLSIIKS PNKTAAPGRF 180
  181 PLQPLPSPSS TFNKRKMDML SPSPSPSTSP QRSKSSFTQQ GTRQKANSLS FAIGASSLRL 240
  241 KKSPLKVPSR PQFKKRSSYY NQNMSAEMRK NRKKSGTISS YDVQTNSEDF PIPAIENGSF 300
  301 DNTLFNPSRF PMDAMSAATN DNFMNNSDIF QN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
phospholipase A2 activity 2.22630563405125 bayes_pls_golite062009
phospholipase activity 2.02363770793596 bayes_pls_golite062009
lipase activity 1.83391969295473 bayes_pls_golite062009
catalytic activity 1.681309422157 bayes_pls_golite062009
[acyl-carrier-protein] S-malonyltransferase activity 1.27314027329282 bayes_pls_golite062009
S-malonyltransferase activity 1.27314027329282 bayes_pls_golite062009
malonyltransferase activity 1.27314027329282 bayes_pls_golite062009
hydrolase activity 0.755660272658182 bayes_pls_golite062009
fatty acid synthase activity 0.432469017757431 bayes_pls_golite062009
carboxylesterase activity 0.431665185524913 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.39017969987234 bayes_pls_golite062009
S-acyltransferase activity 0.28475890150768 bayes_pls_golite062009
binding 0.112552746544258 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [572-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDLEESSSNS LSIIKSPNKT AAPGRFPLQP LPSPSSTFNK RKMDMLSPSP SPSTSPQRSK  60
   61 SSFTQQGTRQ KANSLSFAIG ASSLRLKKSP LKVPSRPQFK KRSSYYNQNM SAEMRKNRKK 120
  121 SGTISSYDVQ TNSEDFPIPA IENGSFDNTL FNPSRFPMDA MSAATNDNFM NNSDIFQN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle