| Protein: | FRE7 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 629 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRE7.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..629] | [1..629] |
|
|
0.0 | [60..609] | [259..867] |
|
|
0.0 | [64..609] | [315..921] |
|
|
0.0 | [64..609] | [315..921] |
|
|
0.0 | [60..609] | [306..939] |
|
|
0.0 | [61..609] | [304..938] |
|
Region A: Residues: [1-78] |
1 11 21 31 41 51
| | | | | |
1 MIEERDLVLS NGIHCIADIH SELYARLKKE SQAATPWVYQ KQYGKFVTYF VAVIIFLSLI 60
61 KKLAFMYYDS SEEFLPEK
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.711 | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.674 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.568 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.530 | a.126.1 | Serum albumin-like |
| View | Download | 0.440 | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.419 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.416 | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.394 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.379 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.375 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.372 | a.77.1 | DEATH domain |
| View | Download | 0.371 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.370 | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.363 | a.64.1 | Saposin |
| View | Download | 0.357 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.332 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.331 | a.4.1 | Homeodomain-like |
| View | Download | 0.322 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.314 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.307 | c.47.1 | Thioredoxin-like |
| View | Download | 0.303 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.295 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.294 | a.65.1 | Annexin |
| View | Download | 0.289 | a.77.1 | DEATH domain |
| View | Download | 0.288 | a.7.8 | GAT domain |
| View | Download | 0.285 | d.150.1 | 4'-phosphopantetheinyl transferase |
| View | Download | 0.283 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.273 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.273 | c.55.4 | Translational machinery components |
| View | Download | 0.270 | a.64.1 | Saposin |
| View | Download | 0.267 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.267 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.262 | a.2.3 | Chaperone J-domain |
| View | Download | 0.257 | g.57.1 | Serine proteinase inhibitor lekti |
| View | Download | 0.253 | a.2.7 | tRNA-binding arm |
| View | Download | 0.250 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.250 | a.39.1 | EF-hand |
| View | Download | 0.248 | a.1.1 | Globin-like |
| View | Download | 0.245 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.239 | a.59.1 | PAH2 domain |
| View | Download | 0.237 | g.53.1 | TAZ domain |
| View | Download | 0.237 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.232 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.221 | a.112.1 | Description not found. |
| View | Download | 0.221 | d.68.3 | SirA-like |
| View | Download | 0.219 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.218 | a.47.2 | t-snare proteins |
| View | Download | 0.218 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.217 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.215 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.214 | a.4.1 | Homeodomain-like |
| View | Download | 0.212 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.210 | a.30.1 | ROP protein |
| View | Download | 0.208 | a.2.7 | tRNA-binding arm |
| View | Download | 0.207 | g.39.1 | Glucocorticoid receptor-like (DNA-binding domain) |
| View | Download | 0.204 | d.58.11 | EF-G/eEF-2 domains III and V |
|
Region A: Residues: [79-314] |
1 11 21 31 41 51
| | | | | |
1 KNSPTTPSVF LARIMTKLVA FNRYICYRKF PTLIFSYLGI PTSVGTFLVV MATTLYTLLY 60
61 CFVPHPFYRP CAGFGSPPLS VRAGIMAISL VPFVFSLSGK INVIGWLVGL SYEKINIYHQ 120
121 WASILCLFFS WVHVIPFLRQ ARHEGGYERM HQRWKASDMW RSGVPPILFL NLLWLSSLPI 180
181 ARRHFYEIFL QLHWILAVGF YISLFYHVYP ELNSHMYLVA TIVVWFAQLF YRLAVK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| hydrogen ion transmembrane transporter activity | 6.63598598376927 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 5.19676916929792 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 5.11036789264445 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 4.7380339483684 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 4.70584841199534 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 4.14430124170869 | bayes_pls_golite062009 |
| transporter activity | 3.25025513931324 | bayes_pls_golite062009 |
| transmembrane transporter activity | 3.15068691999889 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.88166365184739 | bayes_pls_golite062009 |
| binding | 0.727993437899833 | bayes_pls_golite062009 |
| catalytic activity | 0.573177797781864 | bayes_pls_golite062009 |
| protein binding | 0.0725249103002593 | bayes_pls_golite062009 |
|
Region A: Residues: [315-413] |
1 11 21 31 41 51
| | | | | |
1 GYLRPGRSFM ASTIANVSIV GEGCVELIVK DVEMAYSPGQ HIFVRTIDKG IISNHPFSIF 60
61 PSAKYPGGIK MLIRAQKGFS KRLYESNDDM KKILIDGPY
|
| Detection Method: | |
| Confidence: | 55.69897 |
| Match: | 1cnf__ |
| Description: | Nitrate reductase core domain; Nitrate reductase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| catalytic activity | 0.911136919465112 | bayes_pls_golite062009 |
| binding | 0.671794680287713 | bayes_pls_golite062009 |
|
Region A: Residues: [414-553] |
1 11 21 31 41 51
| | | | | |
1 GGIERDIRSF TNVYLICSGS GISTCLPFLQ KYGPILHKTN LEVITLDWVV RHREDISWIR 60
61 DEMCTLSNNL RQLFLDGKIV VRIYVCSDST VPGIIKTFPQ TIDTASDQSD LAKREKDTEF 120
121 GQDDTESNST FDKSNNEYKG
|
| Detection Method: | |
| Confidence: | 55.69897 |
| Match: | 1cnf__ |
| Description: | Nitrate reductase core domain; Nitrate reductase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [554-629] |
1 11 21 31 41 51
| | | | | |
1 LITIIPSKPD LNQVINDYQI GFRNCFICSG SDSLRYTVGN SVAVYRPRFF LTKMSKSAIY 60
61 TARVLATSRK QMASTM
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.352 | c.51.3 | B12-dependend dehydatases associated subunit |
| View | Download | 0.341 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.338 | b.11.1 | gamma-Crystallin-like |
| View | Download | 0.290 | c.52.2 | tRNA splicing endonuclease, C-terminal domain |
| View | Download | 0.277 | d.82.1 | Copper amine oxidase, domain N |
| View | Download | 0.266 | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.261 | b.60.1 | Lipocalins |
| View | Download | 0.259 | d.82.2 | Frataxin-like |
| View | Download | 0.250 | b.71.1 | Glycosyl hydrolase domain |
| View | Download | 0.249 | d.129.1 | TATA-box binding protein-like |
| View | Download | 0.245 | d.58.17 | Metal-binding domain |
| View | Download | 0.244 | d.58.2 | Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain |
| View | Download | 0.242 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.232 | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.224 | c.47.1 | Thioredoxin-like |
| View | Download | 0.216 | b.1.1 | Immunoglobulin |
| View | Download | 0.211 | d.93.1 | SH2 domain |
