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View Structure Prediction Details

Protein: CTR9
Organism: Saccharomyces cerevisiae
Length: 1077 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CTR9.

Description E-value Query
Range
Subject
Range
CTR9 - Component of the Paf1p complex that binds to and modulates the activity of RNA polymerases I and II;...
0.0 [1..1077] [1..1077]
CG6915-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6915 (CG6915, FBgn0035898). It is a protein...
1.0E-82 [17..1047] [18..1086]
TPR1_SCHPO - Tetratricopeptide repeat protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tpr1 PE...
tpr1 - RNA polymerase II associated Paf1 complex subunit Tpr1
4.0E-82 [19..1072] [14..1029]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-82 [19..1072] [14..1029]
gi|13775066 - gi|13775066|gb|AAK39123.1|AF363030_1 UDP-N-acetylglucosaminyltransferase [Mus musculus]
2.0E-81 [261..796] [18..524]
OGT1_RAT - UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Rattus norvegicu...
3.0E-81 [259..796] [6..514]
OGT - O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylgluco...
gi|123993895, gi... - gi|224487755|dbj|BAH24112.1| O-linked N-acetylglucosamine (GlcNAc) transferase [synthetic construct]...
3.0E-81 [259..796] [6..514]

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Predicted Domain #1
Region A:
Residues: [1-128]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNAMKVEGY PSMEWPTSLD IPLKASEELV GIDLETDLPD DPTDLKTLLV EENSEKEHWL  60
   61 TIALAYCNHG KTNEGIKLIE MALDVFQNSE RASLHTFLTW AHLNLAKGQS LSVETKEHEL 120
  121 TQAELNLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.39794
Match: 1elrA_
Description: Hop
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [129-266]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAIGFDPTWI GNMLATVELY YQRGHYDKAL ETSDLFVKSI HAEDHRSGRQ SKPNCLFLLL  60
   61 RAKLLYQKEN YMASLKIFQE LLVINPVLQP DPRIGIGLCF WQLKDSKMAI KSWQRALQLN 120
  121 PKNTSASILV LLGEFRES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [267-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTNSTNDKTF KEAFTKALSD LNNIFSENQH NPVLLTLLQT YYYFKGDYQT VLDIYHHRIL  60
   61 KMSPMIAKIV LSESSFWCGR AHYALG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription elongation regulator activity 5.39627565324437 bayes_pls_golite062009
RNA polymerase II transcription elongation factor activity 3.27203876848788 bayes_pls_golite062009
binding 2.45002000313605 bayes_pls_golite062009
transcription regulator activity 2.36976362065221 bayes_pls_golite062009
DNA binding 1.72247907299633 bayes_pls_golite062009
nucleic acid binding 1.63537681687141 bayes_pls_golite062009
protein binding 1.41340296563325 bayes_pls_golite062009
transcription factor activity 1.0205750374806 bayes_pls_golite062009
N-acetyltransferase activity 0.597017459591015 bayes_pls_golite062009
transcription factor binding 0.447234745044969 bayes_pls_golite062009
N-acyltransferase activity 0.36489074781643 bayes_pls_golite062009
transcription cofactor activity 0.201108481303385 bayes_pls_golite062009
transcription coactivator activity 0.0645101607447045 bayes_pls_golite062009
transcription activator activity 0.0514451541233234 bayes_pls_golite062009
acetyltransferase activity 0.0217632433282022 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [353-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYRKSFIMFQ ESLKKNEDNL LAKLGLGQTQ IKNNLLEESI ITFENLYKTN ESLQELNYIL  60
   61 GMLYAGKAFD AKTAKNTSAK EQSNLNEKAL KYLERYLKLT LATKNQLVIS RAYLVISQLY 120
  121 ELQNQYKTSL DYLSKALEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1fchA_
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [492-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFIKKEIPL EVLNNLACYH FINGDFIKAD DLFKQAKAKV SDKDESVNIT LE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.394 a.5.2 UBA-like
View Download 0.467 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.254 a.144.1 PABC (PABP) domain
View Download 0.266 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.279 g.1.1 Insulin-like
View Download 0.253 a.140.2 SAP domain
View Download 0.203 d.47.1 Ribosomal protein L11, N-terminal domain

Predicted Domain #6
Region A:
Residues: [544-629]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YNIARTNEKN DCEKSESIYS QVTSLHPAYI AARIRNLYLK FAQSKIEDSD MSTEMNKLLD  60
   61 LNKSDLEIRS FYGWYLKNSK ERKNNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.30103
Match: 1jcqA_
Description: Protein farnesyltransferase alpha-subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [630-688]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSTTHNKETL VKYNSHDAYA LISLANLYVT IARDGKKSRN PKEQGKSKHS YLKAIQLYQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.30103
Match: 1jcqA_
Description: Protein farnesyltransferase alpha-subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [689-810]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVLQVDPFNI FAAQGLAIIF AESKRLGPAL EILRKVRDSL DNEDVQLNLA HCYLEMREYG  60
   61 KAIENYELVL KKFDNEKTRP HILNLLGRAW YARAIKETSV NFYQKALENA KTALDLFVKE 120
  121 SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #9
Region A:
Residues: [811-1077]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSKFIHSVKF NIALLHFQIA ETLRRSNPKF RTVQQIKDSL EGLKEGLELF RELNDLKEFN  60
   61 MIPKEELEQR IQLGETTMKS ALERSLNEQE EFKKEQRAKI DEARKILEEN ELKEQGWMKQ 120
  121 EEEARRLKLE KQAEEYRKLQ DEAQKIFQVR EAMAISEHNV KDDSDLSDKD NEYDEEQPRQ 180
  181 KRKRSTKTKN SGESKRRKAA KKTLSDSDED DDDVVKKPSH NKGKKSQLSN EFIEDSDEEE 240
  241 AQMSGSEQNK NDDNDENNDN DDNDGLF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.221849
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle