YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: HRP1
Organism: Saccharomyces cerevisiae
Length: 534 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HRP1.

Description E-value Query
Range		 Subject
Range
PABP1_RAT - Polyadenylate-binding protein 1 OS=Rattus norvegicus GN=Pabpc1 PE=1 SV=1
 0.0 [84..508] [15..475]
PABPC4 - poly(A) binding protein, cytoplasmic 4 (inducible form)
 0.0 [71..501] [2..451]
PABP1_MOUSE - Polyadenylate-binding protein 1 OS=Mus musculus GN=Pabpc1 PE=1 SV=2
 0.0 [84..508] [15..475]
gi|19526272 - gi|19526272|gb|AAL89666.1|AF411956_7 polyA-binding protein [Takifugu rubripes]
 0.0 [84..530] [15..498]
gi|64970 - gi|64970|emb|CAA40721.1| polyA binding protein [Xenopus laevis]
 0.0 [84..508] [15..474]

Back

Predicted Domain #1
Region A:
Residues: [1-58] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDEEDFND IYGDDKPTTT EEVKKEEEQN KAGSGTSQLD QLAALQALSS SLNKLNNP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.465 a.4.1 Homeodomain-like
View Download 0.325 a.64.1 Saposin
View Download 0.567 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.392 d.48.1 RecA protein, C-terminal domain
View Download 0.369 a.159.2 FF domain
View Download 0.286 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.285 d.45.1 ClpS-like
View Download 0.281 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.264 a.2.3 Chaperone J-domain
View Download 0.259 a.4.5 "Winged helix" DNA-binding domain
View Download 0.255 a.32.1 Transcription factor IIA (TFIIA), alpha-helical domain
View Download 0.247 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.241 a.153.1 Nuclear receptor coactivator interlocking domain
View Download 0.240 d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.236 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.227 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.224 a.5.2 UBA-like
View Download 0.209 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.206 d.58.7 RNA-binding domain, RBD

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.51665560478175 bayes_pls_golite062009
4.45006565905155 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
poly-pyrimidine tract binding 2.79052809544187 bayes_pls_golite062009
structural molecule activity 2.78501986457503 bayes_pls_golite062009
transcription regulator activity 1.7776932219095 bayes_pls_golite062009
DNA binding 1.65208390030564 bayes_pls_golite062009
snRNA binding 1.44241647066188 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
transcription factor activity 0.795084003256395 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
sequence-specific DNA binding 0.304235325881492 bayes_pls_golite062009
U1 snRNA binding 0.290135317640781 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [59-152] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSNNSSSNNS NQDTSSSKQD GTANDKEGSN EDTKNEKKQE SATSANANAN ASSAGPSGLP  60
   61 WEQLQQTMSQ FQQPSSQSPP QQQVTQTKEE RSKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 167.39794
Match: 1cvjA_
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [153-244] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLSKESCKMF IGGLNWDTTE DNLREYFGKY GTVTDLKIMK DPATGRSRGF GFLSFEKPSS  60
   61 VDEVVKTQHI LDGKVIDPKR AIPRDEQDKT GK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 402.9794
Match: 2up1A_
Description: Nuclear ribonucleoprotein A1 (RNP A1, UP1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.51665560478175 bayes_pls_golite062009
4.45006565905155 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
poly-pyrimidine tract binding 2.79052809544187 bayes_pls_golite062009
structural molecule activity 2.78501986457503 bayes_pls_golite062009
transcription regulator activity 1.7776932219095 bayes_pls_golite062009
DNA binding 1.65208390030564 bayes_pls_golite062009
snRNA binding 1.44241647066188 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
transcription factor activity 0.795084003256395 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
sequence-specific DNA binding 0.304235325881492 bayes_pls_golite062009
U1 snRNA binding 0.290135317640781 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [245-347] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFVGGIGPDV RPKEFEEFFS QWGTIIDAQL MLDKDTGQSR GFGFVTYDSA DAVDRVCQNK  60
   61 FIDFKDRKIE IKRAEPRHMQ QKSSNNGGNN GGNNMNRRGG NFG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1qm9A_
Description: Polypyrimidine tract-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [348-429] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQGDFNQMYQ NPMMGGYNPM MNPQAMTDYY QKMQEYYQQM QKQTGMDYTQ MYQQQMQQMA  60
   61 MMMPGFAMPP NAMTLNQPQQ DS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1qm9A_
Description: Polypyrimidine tract-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [430-534] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NATQGSPAPS DSDNNKSNDV QTIGNTSNTD SGSPPLNLPN GPKGPSQYND DHNSGYGYNR  60
   61 DRGDRDRNDR DRDYNHRSGG NHRRNGRGGR GGYNRRNNGY HPYNR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle