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View Structure Prediction Details

Protein: YOL075C
Organism: Saccharomyces cerevisiae
Length: 1294 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YOL075C.

Description E-value Query
Range
Subject
Range
PDR5 - Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by ...
PDR5_YEAST - Pleiotropic ABC efflux transporter of multiple drugs OS=Saccharomyces cerevisiae (strain ATCC 204508...
0.0 [4..1293] [138..1505]
gi|6175524 - gi|6175524|gb|AAF05069.1|AF109723_1 ATP-binding cassette transporter [Candida glabrata]
0.0 [1..1292] [121..1492]
gi|18249649 - gi|18249649|dbj|BAA31254.2| PMR1 [Penicillium digitatum]
0.0 [39..1291] [141..1473]
CDR4_CANAX - ABC transporter CDR4 OS=Candida albicans GN=CDR4 PE=3 SV=1
0.0 [4..1292] [135..1481]
gi|14456048 - gi|14456048|emb|CAC41639.1| BcatrD protein [Botryotinia fuckeliana]
0.0 [20..1291] [139..1477]
gi|14530067 - gi|14530067|emb|CAC42217.1| ABC transporter protein [Emericella nidulans]
0.0 [37..1287] [177..1487]

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Predicted Domain #1
Region A:
Residues: [1-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQQENGDVA TELIENRLSF SRIPRISLHV RDLSIVASKT NTTLVNTFSM DLPSGSVMAV  60
   61 MGGSGSGKTT LLNVLASKIS GGLTHNGSIR YVLEDTGSEP NETEPKRAHL DGQDHPIQKH 120
  121 VIMAYLPQQD VLSPRLTCRE TLKFAADLKL NSSERTKKLM VEQLIEELGL KDCADTLVGD 180
  181 NSHRGLSGGE KRRLSIGTQM ISNPSIMFLD EPTTGLDAYS AFLVIKTLKK LAKEDGRTFI 240
  241 MSIHQPRSDI LFLLDQVCIL SKGNVVYCDK MDNTIPYFES I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 232.29073
Match: 1l2tA_
Description: MJ0796
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [282-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYHVPQLVNP ADYFIDLSSV DSRSDKEEAA TQSRLNSLID HWHDYERTHL QLQAESYISN  60
   61 ATEIQIQNMT T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [353-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLPFWKQVTV LTRRNFKLNF SDYVTLISTF AEPLIIGTVC GWIYYKPDKS SIGGLRTTTA  60
   61 CLYASTILQC YLYLLFDTYR LCEQDIALYD RERAEGSVTP L

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [476-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSITYFMFGL EADARKFFYQ FAVVFLCQLS CSGLSMLSVA VSRDFSKASL VGNMTFTVLS  60
   61 MGCGFFVNAK VMPVYVRWIK YIAFTWYSFG TLMSSTFTNS YCTTDNLDEC LGNQILEVYG 120
  121 FPRNWITVPA VVLLCWSVGY FVVGAIILYL HKIDITLQNE VKSKQKKIKK KSPTGMKPEI 180
  181 QLLDDVYHQK DLEAEKGKNI H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 151.457575
Match: 1jsqA_
Description: MsbA
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [454-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFIVARKISL FLSDDFAMTM IF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [677-942]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITIKLEDIDL RVIFSAPFSN WKEGNFHHET KEILQSVNAI FKPGMINAIM GPSGSGKSSL  60
   61 LNLISGRLKS SVFAKFDTSG SIMFNDIQVS ELMFKNVCSY VSQDDDHLLA ALTVKETLKY 120
  121 AAALRLHHLT EAERMERTDN LIRSLGLKHC ENNIIGNEFV KGISGGEKRR VTMGVQLLND 180
  181 PPILLLDEPT SGLDSFTSAT ILEILEKLCR EQGKTIIITI HQPRSELFKR FGNVLLLAKS 240
  241 GRTAFNGSPD EMIAYFTELG YNCPSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 151.457575
Match: 1jsqA_
Description: MsbA
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [943-1238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNVADFFLDL ISVNTQNEQN EISSRARVEK ILSAWKANMD NESLSPTPIS EKQQYSQESF  60
   61 FTEYSEFVRK PANLVLAYIV NVKRQFTTTR RSFDSLMARI AQIPGLGVIF ALFFAPVKHN 120
  121 YTSISNRLGL AQESTALYFV GMLGNLACYP TERDYFYEEY NDNVYGIAPF FLAYMTLELP 180
  181 LSALASVLYA VFTVLACGLP RTAGNFFATV YCSFIVTCCG ERLGIMTNTF FERPGFVVNC 240
  241 ISIILSIGTQ MSGLMSLGMS RVLKGFNYLN PVGYTSMIII NFAFPGNLKL TCEDGG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1239-1294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNSDGTCEFA NGHDVLVSYG LVRNTQKYLG IIVCVAIIYR LIAFFILKAK LEWIKW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle