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View Structure Prediction Details

Protein: YOL075C
Organism: Saccharomyces cerevisiae
Length: 1294 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YOL075C.

Description E-value Query
Range
Subject
Range
PDR5 - Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by ...
PDR5_YEAST - Pleiotropic ABC efflux transporter of multiple drugs OS=Saccharomyces cerevisiae (strain ATCC 204508...
0.0 [4..1293] [138..1505]
gi|6175524 - gi|6175524|gb|AAF05069.1|AF109723_1 ATP-binding cassette transporter [Candida glabrata]
0.0 [1..1292] [121..1492]
gi|18249649 - gi|18249649|dbj|BAA31254.2| PMR1 [Penicillium digitatum]
0.0 [39..1291] [141..1473]
CDR4_CANAX - ABC transporter CDR4 OS=Candida albicans GN=CDR4 PE=3 SV=1
0.0 [4..1292] [135..1481]
gi|14456048 - gi|14456048|emb|CAC41639.1| BcatrD protein [Botryotinia fuckeliana]
0.0 [20..1291] [139..1477]
gi|14530067 - gi|14530067|emb|CAC42217.1| ABC transporter protein [Emericella nidulans]
0.0 [37..1287] [177..1487]

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Predicted Domain #1
Region A:
Residues: [1-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQQENGDVA TELIENRLSF SRIPRISLHV RDLSIVASKT NTTLVNTFSM DLPSGSVMAV  60
   61 MGGSGSGKTT LLNVLASKIS GGLTHNGSIR YVLEDTGSEP NETEPKRAHL DGQDHPIQKH 120
  121 VIMAYLPQQD VLSPRLTCRE TLKFAADLKL NSSERTKKLM VEQLIEELGL KDCADTLVGD 180
  181 NSHRGLSGGE KRRLSIGTQM ISNPSIMFLD EPTTGLDAYS AFLVIKTLKK LAKEDGRTFI 240
  241 MSIHQPRSDI LFLLDQVCIL SKGNVVYCDK MDNTIPYFES I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 232.29073
Match: 1l2tA_
Description: MJ0796
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [282-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYHVPQLVNP ADYFIDLSSV DSRSDKEEAA TQSRLNSLID HWHDYERTHL QLQAESYISN  60
   61 ATEIQIQNMT T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.618 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.565 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.572 a.16.1 S15/NS1 RNA-binding domain
View Download 0.614 a.7.7 BAG domain
View Download 0.790 a.29.4 RecG, N-terminal domain
View Download 0.544 a.112.1 Description not found.
View Download 0.537 a.29.4 RecG, N-terminal domain
View Download 0.527 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.509 a.112.1 Description not found.
View Download 0.494 a.16.1 S15/NS1 RNA-binding domain
View Download 0.493 a.16.1 S15/NS1 RNA-binding domain
View Download 0.477 a.16.1 S15/NS1 RNA-binding domain
View Download 0.477 a.16.1 S15/NS1 RNA-binding domain
View Download 0.470 a.4.5 "Winged helix" DNA-binding domain
View Download 0.469 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.457 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.454 a.112.1 Description not found.
View Download 0.444 a.16.1 S15/NS1 RNA-binding domain
View Download 0.444 a.16.1 S15/NS1 RNA-binding domain
View Download 0.432 a.16.1 S15/NS1 RNA-binding domain
View Download 0.428 a.4.1 Homeodomain-like
View Download 0.419 a.16.1 S15/NS1 RNA-binding domain
View Download 0.418 a.16.1 S15/NS1 RNA-binding domain
View Download 0.417 a.16.1 S15/NS1 RNA-binding domain
View Download 0.417 a.16.1 S15/NS1 RNA-binding domain
View Download 0.408 a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.404 a.7.6 Ribosomal protein S20
View Download 0.401 a.16.1 S15/NS1 RNA-binding domain
View Download 0.401 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.396 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.392 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.387 a.4.5 "Winged helix" DNA-binding domain
View Download 0.382 a.17.1 p8-MTCP1
View Download 0.382 a.126.1 Serum albumin-like
View Download 0.381 a.101.1 Uteroglobin-like
View Download 0.372 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.371 a.16.1 S15/NS1 RNA-binding domain
View Download 0.370 a.16.1 S15/NS1 RNA-binding domain
View Download 0.365 a.47.2 t-snare proteins
View Download 0.364 a.47.2 t-snare proteins
View Download 0.362 a.47.2 t-snare proteins
View Download 0.355 a.112.1 Description not found.
View Download 0.349 d.34.1 DNA-binding domain of Mlu1-box binding protein MBP1
View Download 0.344 a.126.1 Serum albumin-like
View Download 0.342 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.342 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.340 a.105.1 FIS-like
View Download 0.337 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.336 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.332 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.330 a.4.5 "Winged helix" DNA-binding domain
View Download 0.323 a.77.1 DEATH domain
View Download 0.314 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.305 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.305 a.4.5 "Winged helix" DNA-binding domain
View Download 0.302 a.47.2 t-snare proteins
View Download 0.299 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.299 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.294 a.77.1 DEATH domain
View Download 0.294 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.292 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.288 a.39.1 EF-hand
View Download 0.286 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.285 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.285 a.17.1 p8-MTCP1
View Download 0.281 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.281 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.276 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.269 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.256 a.47.2 t-snare proteins
View Download 0.256 a.24.17 Group V grass pollen allergen
View Download 0.253 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.250 f.15.1 Small-conductance potassium channel
View Download 0.248 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.245 a.47.2 t-snare proteins
View Download 0.244 a.28.2 Colicin E immunity proteins
View Download 0.244 a.28.2 Colicin E immunity proteins
View Download 0.243 a.16.1 S15/NS1 RNA-binding domain
View Download 0.242 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.241 d.15.2 CAD & PB1 domains
View Download 0.239 a.7.7 BAG domain
View Download 0.238 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.235 d.64.1 eIF1-like
View Download 0.234 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.233 a.24.17 Group V grass pollen allergen
View Download 0.232 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.232 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.230 a.30.1 ROP protein
View Download 0.230 a.30.1 ROP protein
View Download 0.230 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.228 a.156.1 S13-like H2TH domain
View Download 0.225 f.15.1 Small-conductance potassium channel
View Download 0.224 d.52.1 Alpha-lytic protease prodomain
View Download 0.223 a.46.1 Methionine synthase domain
View Download 0.221 f.13.1 Family A G protein-coupled receptor-like
View Download 0.221 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.221 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.220 f.15.1 Small-conductance potassium channel
View Download 0.220 a.24.17 Group V grass pollen allergen
View Download 0.219 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.218 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.217 a.28.2 Colicin E immunity proteins
View Download 0.215 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.214 a.21.1 HMG-box
View Download 0.214 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.213 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.212 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.212 d.201.1 SRP19
View Download 0.211 f.15.1 Small-conductance potassium channel
View Download 0.210 f.15.1 Small-conductance potassium channel
View Download 0.208 a.28.2 Colicin E immunity proteins
View Download 0.207 a.28.2 Colicin E immunity proteins
View Download 0.206 a.47.2 t-snare proteins
View Download 0.206 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.204 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.202 d.58.1 4Fe-4S ferredoxins
View Download 0.201 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3

Predicted Domain #3
Region A:
Residues: [353-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLPFWKQVTV LTRRNFKLNF SDYVTLISTF AEPLIIGTVC GWIYYKPDKS SIGGLRTTTA  60
   61 CLYASTILQC YLYLLFDTYR LCEQDIALYD RERAEGSVTP L

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [476-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSITYFMFGL EADARKFFYQ FAVVFLCQLS CSGLSMLSVA VSRDFSKASL VGNMTFTVLS  60
   61 MGCGFFVNAK VMPVYVRWIK YIAFTWYSFG TLMSSTFTNS YCTTDNLDEC LGNQILEVYG 120
  121 FPRNWITVPA VVLLCWSVGY FVVGAIILYL HKIDITLQNE VKSKQKKIKK KSPTGMKPEI 180
  181 QLLDDVYHQK DLEAEKGKNI H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 151.457575
Match: 1jsqA_
Description: MsbA
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [454-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFIVARKISL FLSDDFAMTM IF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [677-942]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITIKLEDIDL RVIFSAPFSN WKEGNFHHET KEILQSVNAI FKPGMINAIM GPSGSGKSSL  60
   61 LNLISGRLKS SVFAKFDTSG SIMFNDIQVS ELMFKNVCSY VSQDDDHLLA ALTVKETLKY 120
  121 AAALRLHHLT EAERMERTDN LIRSLGLKHC ENNIIGNEFV KGISGGEKRR VTMGVQLLND 180
  181 PPILLLDEPT SGLDSFTSAT ILEILEKLCR EQGKTIIITI HQPRSELFKR FGNVLLLAKS 240
  241 GRTAFNGSPD EMIAYFTELG YNCPSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 151.457575
Match: 1jsqA_
Description: MsbA
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [943-1238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNVADFFLDL ISVNTQNEQN EISSRARVEK ILSAWKANMD NESLSPTPIS EKQQYSQESF  60
   61 FTEYSEFVRK PANLVLAYIV NVKRQFTTTR RSFDSLMARI AQIPGLGVIF ALFFAPVKHN 120
  121 YTSISNRLGL AQESTALYFV GMLGNLACYP TERDYFYEEY NDNVYGIAPF FLAYMTLELP 180
  181 LSALASVLYA VFTVLACGLP RTAGNFFATV YCSFIVTCCG ERLGIMTNTF FERPGFVVNC 240
  241 ISIILSIGTQ MSGLMSLGMS RVLKGFNYLN PVGYTSMIII NFAFPGNLKL TCEDGG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1239-1294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNSDGTCEFA NGHDVLVSYG LVRNTQKYLG IIVCVAIIYR LIAFFILKAK LEWIKW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.397 a.2.10 Epsilon subunit of F1F0-ATP synthase C-terminal domain
View Download 0.480 d.42.1 POZ domain
View Download 0.441 a.16.1 S15/NS1 RNA-binding domain
View Download 0.687 a.4.11 RNA polymerase subunit RPB10
View Download 0.432 d.42.1 POZ domain
View Download 0.369 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.341 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.336 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.314 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.313 a.4.1 Homeodomain-like
View Download 0.295 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.288 d.15.7 Immunoglobulin-binding domains
View Download 0.288 d.15.7 Immunoglobulin-binding domains
View Download 0.279 d.15.7 Immunoglobulin-binding domains
View Download 0.270 a.144.1 PABC (PABP) domain
View Download 0.261 a.144.2 Ribosomal protein L20
View Download 0.229 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.228 a.4.5 "Winged helix" DNA-binding domain
View Download 0.216 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.210 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.204 a.16.1 S15/NS1 RNA-binding domain
View Download 0.200 d.15.1 Ubiquitin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle