YRC Public Data Repository - Protein Structure Prediction

Protein:	ESC8
Organism:	Saccharomyces cerevisiae
Length:	714 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ESC8.

Description	E-value	Query Range	Subject Range
IOC3 - Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses ... IOC3_YEAST - ISWI one complex protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IOC3 PE=1 SV=...	774.0	[0..67]	[557..94]
gi\|49527989 - gi\|49527989\|emb\|CAG61640.1\| unnamed protein product [Candida glabrata] gi\|50292489, gi\|... - gi\|50292489\|ref\|XP_448677.1\| unnamed protein product [Candida glabrata], gi\|49527989\|emb\|CAG61640.1\|...	392.0	[0..112]	[557..112]
gi\|45199124, gi\|... - gi\|45199124\|ref\|NP_986153.1\| AFR606Cp [Ashbya gossypii ATCC 10895], gi\|44985264\|gb\|AAS53977.1\| AFR60... gi\|44985264 - gi\|44985264\|gb\|AAS53977.1\| AFR606Cp [Ashbya gossypii ATCC 10895]	376.0	[0..33]	[570..35]
gi\|49645249 - gi\|49645249\|emb\|CAG98821.1\| KLLA0F23199p [Kluyveromyces lactis] gi\|49645249, gi\|... - gi\|50312163\|ref\|XP_456113.1\| unnamed protein product [Kluyveromyces lactis], gi\|49645249\|emb\|CAG9882...	347.0	[0..82]	[576..179]
gi\|50425575, gi\|... - gi\|50425575\|ref\|XP_461383.1\| hypothetical protein DEHA0F25388g [Debaryomyces hansenii CBS767], gi\|49...	98.0	[0..164]	[630..419]
orf19.9806 - orf19.2266 CGDID:CAL0006322 Assembly 19, Contig19-20143 (63353, 60861) CDS, reverse complemented, tr... gi\|46436388, gi\|... - gi\|68482569\|ref\|XP_714794.1\| hypothetical protein CaO19.9806 [Candida albicans SC5314], gi\|46436388\|...	86.0	[0..63]	[564..248]

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Predicted Domain #1

Region A:
Residues: [1-599]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEIIDLDLV DDFIKKPMVK QQKNQSSKPR VKRRGQLTFD DFRNIKIVEE PVVLSHNSSI  60
   61 DESLDAATQN TKKREKYEGT CDEEMKTKEM EANMASKYSN IKTHSNDTNK VESISEHTTS 120
  121 NNRPLNTLNW SPNIPLRYSD FAKFMSDETV TESNWAPPLC TPLPYAGDVM KILSFIVKFK 180
  181 WVFSDDLLNL SFQDVEIGLE LKVAGHSAKN IRICQDKMNL LFCSLLRLLF CSEKRADNQT 240
  241 HRNFTLKRFL SLKNPYGKLV GKLRSLIQEW GLPKEWRGNS DILSTLNFNG GGLLTMEPLD 300
  301 RIILLRCMID WNCSYSALFH NEIQRLTHLK GDTGFNHQTF HASRFAMCGA NNILDSCEVL 360
  361 CSLMSQKLEN RKKRKPSDKG KLSKINSQMK FLKGVRKSLS EKVTTDRLRA AVKINEEWGE 420
  421 YFANEFTHTP IDDPTVDEIY KLRTSEFMIA RIPRVGDFYL PPFWIGNECS SVNTSYSFND 480
  481 MSTYLNYFVK FKEEGTKILP AKTAQNENKC QLKLIYRNTP ACIRNLQFND VHFAEVPHWF 540
  541 EVAGDSNSLS NFIEYLESLS SLTENDTDDT KKGIDNLIEF LKIFSIFINE TIQRITAAP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [600-714]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGSTEGRHLR TSSQRRTTVH YSSDVNGDVS EESENEVDID VSDDYDSEYL SEENTLTRKG  60
   61 EDRTDKSFGK RELHNGAKDC DRNCDDIEIF SEPVRQLQDN SREKRSLRRN ARKGL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits