YRC Public Data Repository - Protein Structure Prediction

Protein:	IZH2
Organism:	Saccharomyces cerevisiae
Length:	327 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IZH2.

Description	E-value	Query Range	Subject Range
ADR1_MOUSE - Adiponectin receptor protein 1 OS=Mus musculus GN=Adipor1 PE=1 SV=1	5.0E-87	[16..318]	[59..363]
paqr-1 - status:Partially_confirmed UniProt:Q94177 protein_id:AAB09107.2	5.0E-83	[16..317]	[127..426]
gi\|18377749 - gi\|18377749\|gb\|AAL67024.1\| unknown protein [Arabidopsis thaliana]	3.0E-68	[15..317]	[1..350]
IZH1_YEAST - ADIPOR-like receptor IZH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IZH1 PE=1 SV=1 gi\|207346210 - gi\|207346210\|gb\|EDZ72775.1\| YDR492Wp-like protein [Saccharomyces cerevisiae AWRI1631] IZH1 - Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family; transcript...	2.0E-67	[11..319]	[1..312]
ADRL_SCHPO - ADIPOR-like receptor SPBC12C2.09c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC12C2... SPBC12C2.09c - Haemolysin-III family protein	3.0E-67	[26..318]	[27..316]

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Predicted Domain #1

Region A:
Residues: [1-72]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHVGEESFQ MSTLLERTKS VQELKKRAAG KTSANPAEVA KAKKVLRRLY SWDEIPEWQR  60
   61 DNDFILHGYV KE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [73-327]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSFIETFKS LFYLHNESVN IYSHLIPALG FFTVLLLDKS TIKVFATTTW LDHMVIDLFY  60
   61 SGAFACLILS SSFHCLKSHS LRIATLGNKL DYLGICILIV TSMVSILYYG YFEKFSLFCL 120
  121 FALITVSFGI ACSIVSLKDK FRKREWRPYR AGLFVCFGLS SIIPIFSGLY CYSFSEIWTQ 180
  181 IQLFWVLLGG VLYIIGAVLY GMRFPEKICP GKFDIWGHSH QLFHFLVVIA ALCHLRGLLN 240
  241 SYELVHIKME NGIVS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	126.39794
Match:	PF03006
Description:	Haemolysin-III related

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits