YRC Public Data Repository - Protein Structure Prediction

Protein:	NOG2
Organism:	Saccharomyces cerevisiae
Length:	486 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NOG2.

Description	E-value	Query Range	Subject Range
NOG2_YEAST - Nucleolar GTP-binding protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOG2 PE=... NOG2 - Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for...	0.0	[1..467]	[1..467]
NOG2_SCHPO - Nucleolar GTP-binding protein 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nog2 PE=1 ... SPAC6F6.03c - ribosome export GTPase	0.0	[1..468]	[1..463]
NOG2_MOUSE - Nucleolar GTP-binding protein 2 OS=Mus musculus GN=Gnl2 PE=2 SV=1	2.0E-95	[26..478]	[29..472]
GNL2 - guanine nucleotide binding protein-like 2 (nucleolar)	8.0E-94	[26..472]	[29..466]
NOG2_PNECA - Nucleolar GTP-binding protein 2 OS=Pneumocystis carinii GN=NOG2 PE=2 SV=1	6.0E-93	[18..468]	[7..446]
NUG2_ARATH - Nuclear/nucleolar GTPase 2 OS=Arabidopsis thaliana GN=NUG2 PE=1 SV=1	2.0E-84	[31..472]	[33..465]
gi\|85014445, gi\|... - gi\|85014445\|ref\|XP_955718.1\| GTP-binding protein [Encephalitozoon cuniculi GB-M1], gi\|19171412\|emb\|C... gi\|19173286 - ref\|NP_597089.1\| similarity to HYPOTHETICAL GTP-BINDING PROTEIN YN8U_yeast [Encephalitozoon cuniculi...	2.0E-76	[27..474]	[10..417]
DER_CLOPE, ENGA_... - GTP-binding protein engA OS=Clostridium perfringens GN=engA PE=3 SV=1, GTPase Der OS=Clostridium per... DER_CLOP1 - GTPase Der OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 82... DER_CLOPS - GTPase Der OS=Clostridium perfringens (strain SM101 / Type A) GN=der PE=3 SV=1 gi\|168217042, gi... - gi\|182380862\|gb\|EDT78341.1\| putative GTP-binding protein Era [Clostridium perfringens NCTC 8239], gi... DER_CLOPE - GTPase Der OS=Clostridium perfringens (strain 13 / Type A) GN=der PE=3 SV=1 gi\|169299237, gi... - gi\|169342731\|ref\|ZP_02863772.1\| putative GTP-binding protein Era [Clostridium perfringens C str. JGS... gi\|177908885, gi... - gi\|182625851\|ref\|ZP_02953617.1\| putative GTP-binding protein Era [Clostridium perfringens D str. JGS... gi\|170661368, gi... - gi\|170661368\|gb\|EDT14051.1\| putative GTP-binding protein Era [Clostridium perfringens E str. JGS1987... gi\|170711316, gi... - gi\|170711316\|gb\|EDT23498.1\| putative GTP-binding protein Era [Clostridium perfringens B str. ATCC 36... gi\|170714259, gi... - gi\|170714259\|gb\|EDT26441.1\| putative GTP-binding protein Era [Clostridium perfringens CPE str. F4969...	4.0E-64	[144..458]	[6..341]

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Predicted Domain #1

Region A:
Residues: [1-112]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTGKKEKSR RIREGDTKDG NLRVKGENFY RDSKRVKFLN MYTSGKEIRN KKGNLIRAAS  60
   61 FQDSTIPDAR VQPDRRWFGN TRVISQDALQ HFRSALGETQ KDTYQVLLRR NK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [113-312]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPMSLLEEKD ADESPKARIL DTESYADAFG PKAQRKRPRL AASNLEDLVK ATNEDITKYE  60
   61 EKQVLDATLG LMGNQEDKEN GWTSAAKEAI FSKGQSKRIW NELYKVIDSS DVVIHVLDAR 120
  121 DPLGTRCKSV EEYMKKETPH KHLIYVLNKC DLVPTWVAAA WVKHLSKERP TLAFHASITN 180
  181 SFGKGSLIQL LRQFSQLHTD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.522879
Match:	1jah__
Description:	cH-p21 Ras protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [313-486]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKQISVGFIG YPNTGKSSII NTLRKKKVCQ VAPIPGETKV WQYITLMKRI FLIDCPGIVP  60
   61 PSSKDSEEDI LFRGVVRVEH VTHPEQYIPG VLKRCQVKHL ERTYEISGWK DATEFIEILA 120
  121 RKQGRLLKGG EPDESGVSKQ ILNDFNRGKI PWFVLPPEKE GEEKPKKKEV EKTA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.0
Match:	1egaA_
Description:	GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits