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View Structure Prediction Details

Protein: JJJ1
Organism: Saccharomyces cerevisiae
Length: 590 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JJJ1.

Description E-value Query
Range		 Subject
Range
JJJ1_YEAST - J protein JJJ1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=JJJ1 PE=1 SV=1
gi|190409199 - gi|190409199|gb|EDV12464.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
JJJ1 - Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biog...
 0.0 [1..575] [1..575]
CG2790-PA - This gene is referred to in FlyBase by the symbol Dmel\CG2790 (CG2790, FBgn0027599). It is a protein...
gi|220951964 - gi|220951964|gb|ACL88525.1| CG2790-PA [synthetic construct]
 6.0E-61 [3..573] [2..515]
DNAJ_THEVO - Chaperone protein dnaJ OS=Thermoplasma volcanium GN=dnaJ PE=3 SV=1
DNAJ_THEVO - Chaperone protein DnaJ OS=Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 154...
 5.0E-59 [1..221] [1..215]
gi|23505965, gi|... - gi|23505965|gb|AAN28842.1| At1g80030/F18B13_37 [Arabidopsis thaliana], gi|14326568|gb|AAK60328.1|AF3...
 2.0E-56 [4..226] [75..291]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 5.0E-55 [4..232] [71..293]
DNAJ_THEAC - Chaperone protein DnaJ OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 1...
DNAJ_THEAC - Chaperone protein dnaJ OS=Thermoplasma acidophilum GN=dnaJ PE=3 SV=1
 8.0E-55 [1..221] [1..215]
gi|16326131 - gi|16326131|dbj|BAB70509.1| DNAJ homologue [Oryza sativa]
 1.0E-54 [4..225] [90..300]
DNAJ_GEOSE - Chaperone protein DnaJ OS=Geobacillus stearothermophilus GN=dnaJ PE=3 SV=1
 6.0E-54 [2..225] [3..216]

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Predicted Domain #1
Region A:
Residues: [1-119] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTCYYELLG VETHASDLEL KKAYRKKALQ YHPDKNPDNV EEATQKFAVI RAAYEVLSDP  60
   61 QERAWYDSHK EQILNDTPPS TDDYYDYEVD ATVTGVTTDE LLLFFNSALY TKIDNSAAG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 119.512579
Match: 1xbl__
Description: DnaJ chaperone, N-terminal (J) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.00357390808173 bayes_pls_golite062009
unfolded protein binding 1.87268634400658 bayes_pls_golite062009
protein binding 1.5095461875158 bayes_pls_golite062009
transcription regulator activity 0.614892374098773 bayes_pls_golite062009
transporter activity 0.563782869756263 bayes_pls_golite062009
nucleic acid binding 0.546706887747132 bayes_pls_golite062009
DNA binding 0.288048247241731 bayes_pls_golite062009
catalytic activity 0.106988907594358 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [120-256] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IYQIAGKIFA KLAKDEILSG KRLGKFSEYQ DDVFEQDINS IGYLKACDNF INKTDKLLYP  60
   61 LFGYSPTDYE YLKHFYKTWS AFNTLKSFSW KDEYMYSKNY DRRTKREVNR RNEKARQQAR 120
  121 NEYNKTVKRF VVFIKKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 1exkA_
Description: Cysteine-rich domain of the chaperone protein DnaJ.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [257-590] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKRMKEGAKI AEEQRKLKEQ QRKNELNNRR KFGNDNNDEE KFHLQSWQTV KEENWDELEK  60
   61 VYDNFGEFEN SKNDKEGEVL IYECFICNKT FKSEKQLKNH INTKLHKKNM EEIRKEMEEE 120
  121 NITLGLDNLS DLEKFDSADE SVKEKEDIDL QALQAELAEI ERKLAESSSE DESEDDNLNI 180
  181 EMDIEVEDVS SDENVHVNTK NKKKRKKKKK AKVDTETEES ESFDDTKDKR SNELDDLLAS 240
  241 LGDKGLQTDD DEDWSTKAKK KKGKQPKKNS KSTKSTPSLS TLPSSMSPTS AIEVCTTCGE 300
  301 SFDSRNKLFN HVKIAGHAAV KNVVKRKKVK TKRI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle