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View Structure Prediction Details

Protein: RAP1
Organism: Saccharomyces cerevisiae
Length: 827 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAP1.

Description E-value Query
Range
Subject
Range
RAP1 - DNA-binding protein involved in either activation or repression of transcription, depending on bindi...
RAP1_YEAST - DNA-binding protein RAP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAP1 PE=1 SV=2
0.0 [1..827] [1..827]
gi|15100061 - gi|15100061|gb|AAK84226.1|AF401990_1 repressor activator protein 1 [Saccharomyces castellii]
0.0 [1..827] [1..826]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [104..827] [1..666]
gi|50292015, gi|... - gi|50292015|ref|XP_448440.1| RAP1_CANGA [Candida glabrata], gi|49527752|emb|CAG61401.1| RAP1_CANGA [...
gi|15130641, gi|... - gi|49527752|emb|CAG61401.1| unnamed protein product [Candida glabrata], gi|15130641|dbj|BAB62800.1| ...
0.0 [359..827] [231..687]
gi|2827428 - gi|2827428|gb|AAB99849.1| Rap1p [Zygosaccharomyces rouxii]
6.0E-88 [374..536] [1..163]
gi|2827426 - gi|2827426|gb|AAB99848.1| Rap1p [Saccharomyces unisporus]
1.0E-82 [374..537] [1..164]
gi|55715986 - gb|AAH86254.1| Unknown (protein for MGC:98773) [Xenopus laevis]
PESC_MOUSE - Pescadillo homolog OS=Mus musculus GN=Pes1 PE=1 SV=1
0.003 [42..206] [248..412]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPDDFETA PAEYVDALDP SMVVVDSGSA AVTAPSDSAA EVKANQNEEN TGATAAETSE  60
   61 KVDQTEVEKK DDDDTTEVGV TTTTPSIADT AATANIASTS GAS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTEPTTDDTA ADEKKEQVSG PPLSNMKFYL NRDADAHDSL NDIDQLARLI RANGGEVLDS  60
   61 KPRESKENVF IVSPYNHTNL PTVTPTYIKA CCQSNSLLNM ENYLVPYDNF REVVDSRLQE 120
  121 ESHSNGVDNS NSNSDNKDSI RPKTEIISTN TNGATEDSTS EKVMVD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.52
Match: 1imoA
Description: DNA ligase III alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [270-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEQQARLQEQ AQLLRQHVSS TASITSGGHN DLVQIEQPQK DTSNNNNSNV NDEDNDLLTQ  60
   61 DNNPQTADEG N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [341-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASFQAQRSMI SRGALPSHNK ASFTDEEDEF ILDVVRKNPT RRTTHTLYDE ISHYVPNHTG  60
   61 NSIRHRFRVY LSKRLEYVYE VDKFGKLVRD DDGNLIKTKV LPPS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [588-616]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPGNYNSAAK RARNYSSQRN VQPTANAAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1518.0
Match: 1ignA_
Description: DNA-binding domain of rap1
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [445-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKRKFSADED YTLAIAVKKQ FYRDLFQIDP DTGRSLITDE DTPTAIARRN MTMDPNHVPG  60
   61 SEPNFAAYRT QSRRGPIARE FFKHFAEEHA AHTENAWRDR FRKFLLAYGI DDYISYYEAE 120
  121 KAQNREPEPM KNLTNRPKRP GVP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1518.0
Match: 1ignA_
Description: DNA-binding domain of rap1
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [617-827]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANAAAAAAAA ASNSYAIPEN ELLDEDTMNF ISSLKNDLSN ISNSLPFEYP HEIAEAIRSD  60
   61 FSNEDIYDNI DPDTISFPPK IATTDLFLPL FFHFGSTRQF MDKLHEVISG DYEPSQAEKL 120
  121 VQDLCDETGI RKNFSTSILT CLSGDLMVFP RYFLNMFKDN VNPPPNVPGI WTHDDDESLK 180
  181 SNDQEQIRKL VKKHGTGRME MRKRFFEKDL L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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