YRC Public Data Repository - Protein Structure Prediction

Protein:	ESBP6
Organism:	Saccharomyces cerevisiae
Length:	673 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ESBP6.

Description	E-value	Query Range	Subject Range
ESBP6_YEAST - Uncharacterized transporter ESBP6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ESBP6 ... ESBP6 - Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of mon...	0.0	[1..673]	[1..673]
ANTR1_ARATH - Sodium-dependent phosphate transport protein 1, chloroplastic OS=Arabidopsis thaliana GN=ANTR1 PE=1 ...	1.0E-68	[134..605]	[21..504]
gi\|218774566, gi... - gi\|218894337\|ref\|YP_002443207.1\| sn-glycerol-3-phosphate transporter [Pseudomonas aeruginosa LESB58]... gi\|116053382, gi... - gi\|53726696\|ref\|ZP_00141712.2\| COG2271: Sugar phosphate permease [Pseudomonas aeruginosa UCBPP-PA14]... gi\|9951544, gi\|1... - gi\|9951544\|gb\|AAG08620.1\|AE004936_3 glycerol-3-phosphate transporter [Pseudomonas aeruginosa PAO1], ... gi\|107104337 - gi\|107104337\|ref\|ZP_01368255.1\| hypothetical protein PaerPA_01005412 [Pseudomonas aeruginosa PACS2] gi\|84317896, gi\|... - gi\|84317896\|ref\|ZP_00966331.1\| COG2271: Sugar phosphate permease [Pseudomonas aeruginosa C3719], gi\|... gi\|11348631 - pir\|\|B82991 glycerol-3-phosphate transporter PA5235 [imported] - Pseudomonas aeruginosa (strain PAO1... gi\|126197261, gi... - gi\|84324061\|ref\|ZP_00972126.1\| COG2271: Sugar phosphate permease [Pseudomonas aeruginosa 2192], gi\|2...	2.0E-67	[192..617]	[7..446]
gi\|12658422 - gi\|12658422\|gb\|AAK01131.1\|AF331922_2 putative hexuronate transporter [Xanthomonas oryzae pv. oryzae]	1.0E-66	[155..608]	[3..478]
gi\|9657525, gi\|1... - gi\|9657525\|gb\|AAF96050.1\| glycerol-3-phosphate transporter [Vibrio cholerae O1 biovar eltor str. N16... gi\|11277446 - pir\|\|C82495 glycerol-3-phosphate transporter VCA0137 [imported] - Vibrio cholerae (strain N16961 ser...	1.0E-66	[192..621]	[24..468]
gi\|75512715, gi\|... - gi\|75512715\|ref\|ZP_00735217.1\| COG2271: Sugar phosphate permease [Escherichia coli 53638], gi\|188493... gi\|238901413, gi... - gi\|238901413\|ref\|YP_002927209.1\| sn-glycerol-3-phosphate transporter [Escherichia coli BW2952], gi\|2... GLPT_ECOLI - Glycerol-3-phosphate transporter (G-3-P transporter) (G-3-P permease) - Escherichia coli EG10401 - sn-glycerol-3-phosphate transporter / sn-Glycerol-3-phosphate permease; fosfomycin sensitivity gi\|89109057, gi\|... - gi\|89109057\|ref\|AP_002837.1\| sn-glycerol-3-phosphate transporter [Escherichia coli str. K-12 substr.... gi\|124526408, gi... - gi\|124526408\|ref\|ZP_01698361.1\| glycerol-3-phosphate transporter [Escherichia coli B], gi\|124501879\|... gi\|169754375, gi... - gi\|170019447\|ref\|YP_001724401.1\| sn-glycerol-3-phosphate transporter [Escherichia coli ATCC 8739], g... EG10401 - sn-glycerol-3-phosphate transporter / sn-Glycerol-3-phosphate permease; fosfomycin sensitivity gi\|170081858, gi... - gi\|170081858\|ref\|YP_001731178.1\| sn-glycerol-3-phosphate transporter [Escherichia coli str. K-12 sub...	3.0E-66	[192..619]	[7..448]
MOT1_CRILO - Monocarboxylate transporter 1 OS=Cricetulus longicaudatus GN=SLC16A1 PE=1 SV=1 tr\|G3IDS7\|G3IDS7... - Monocarboxylate transporter 1 OS=Cricetulus griseus GN=I79_021860 PE=4 SV=1 gi\|472333 - gi\|472333\|gb\|AAB59731.1\| monocarboxylate transporter 1	5.0E-66	[195..648]	[2..476]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	5.0E-66	[195..648]	[2..476]
gi\|8979037, gi\|1... - gi\|8979037\|dbj\|BAA98872.1\| hexosphosphate transport [Chlamydophila pneumoniae J138], gi\|15836197\|ref... gi\|33242022, gi\|... - gi\|33242022\|ref\|NP_876963.1\| hexose phosphate transport system regulatory protein [Chlamydophila pne... UHPT_CHLPN - Probable hexose phosphate transport protein OS=Chlamydia pneumoniae GN=uhpC PE=3 SV=1 gi\|7189017, gi\|1... - gi\|7189017\|gb\|AAF37968.1\| GlpT/PgpT/UhpT family protein [Chlamydophila pneumoniae AR39], gi\|16752375... gi\|4376965, gi\|1... - gi\|4376965\|gb\|AAD18804.1\| Hexosphosphate Transport [Chlamydophila pneumoniae CWL029], gi\|15618575\|re...	6.0E-66	[197..611]	[16..449]

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Predicted Domain #1

Region A:
Residues: [1-179]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTHSNDYFS ASSGMVSETS SEVSSINSSQ PVSFSKASIA APVPCSDLHS TKSNDASRKL  60
   61 SISRTLTNRL NDIKKAVDDD NLQTEENSAD VNKILESRFD VADAIRLQHN ESVQSKLNIP 120
  121 VTHTTTAGAS LSAPSSSAFS ASSIQNDTTE HKASMDSKLM RNRLYPASTK HSGKDLEAQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [180-673]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GITEFEPDEP TVKKVFTNKS TGQLELPPDG GYGWVVTFCV FLTMFSTWGC NASFGVDLAY  60
   61 YLNHDTYPGA SKYDYALIAG LTVFLGQLLS PLVMALMRII GLRTTMLFGD AVMLAAYLLA 120
  121 SFTTKLWQLY VTQGFMVGCS ISLIFVPATT VLPGWFLKKR AVAMGVSLLG TGAGGVVYGL 180
  181 ATNKMLSDFG NTRWCLRIIG ISCSISVLVA IALLKERNPT PAIGLKSPRA MFEQLKAMFS 240
  241 LKVITKPFVV LIALWFMFAL FAYNMMVFTL SSYAISKGLS SHDASTLTAI LNGSQSIGRP 300
  301 LMGLAGDKFG RANVTIVLTT LLTIYMFAFW IPAHTFVQLI FFSILVGSCV GVANVMNTVL 360
  361 IADMVKPEEF LPAWAFVNYC GAPFLLVCEV IAQALTVEKD KSNPYLHAQI FCGCCFIAAL 420
  421 ILISILREYS IRMKLTERQA MTNEKLKEWK ASEYDTDSAD EDWGKLKERK TKYDLLLGPG 480
  481 IKKYFLRMVY PMKV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.522879
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
binding	0.873217664940684	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: