YRC Public Data Repository - Protein Structure Prediction

Protein:	ASI3
Organism:	Saccharomyces cerevisiae
Length:	669 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ASI3.

Description	E-value	Query Range	Subject Range
ASI1_YEAST - Protein ASI1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ASI1 PE=1 SV=1 ASI1 - Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of ...	919.0	[0..21]	[669..14]
gi\|45198730, gi\|... - gi\|45198730\|ref\|NP_985759.1\| AFR212Wp [Ashbya gossypii ATCC 10895], gi\|44984740\|gb\|AAS53583.1\| AFR21... gi\|44984740 - gi\|44984740\|gb\|AAS53583.1\| AFR212Wp [Ashbya gossypii ATCC 10895]	389.0	[0..22]	[669..9]
gi\|49645010, gi\|... - gi\|50311695\|ref\|XP_455874.1\| unnamed protein product [Kluyveromyces lactis], gi\|49645010\|emb\|CAG9858... gi\|49645010 - gi\|49645010\|emb\|CAG98582.1\| KLLA0F17677p [Kluyveromyces lactis]	341.0	[0..22]	[669..16]
gi\|49527695, gi\|... - gi\|50291901\|ref\|XP_448383.1\| unnamed protein product [Candida glabrata], gi\|49527695\|emb\|CAG61344.1\|... gi\|49527695 - gi\|49527695\|emb\|CAG61344.1\| unnamed protein product [Candida glabrata]	309.0	[0..22]	[667..9]
gi\|49655092, gi\|... - gi\|50421737\|ref\|XP_459424.1\| hypothetical protein DEHA0E02739g [Debaryomyces hansenii CBS767], gi\|49...	124.0	[0..155]	[668..115]
orf19.13798, orf... - orf19.6440 CGDID:CAL0002208 Assembly 19, Contig19-10247 (105879, 103735) CDS, reverse complemented, ... gi\|46437942, gi\|... - gi\|68479666\|ref\|XP_716195.1\| hypothetical protein CaO19.13798 [Candida albicans SC5314], gi\|68479493...	122.0	[0..155]	[668..113]

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Predicted Domain #1

Region A:
Residues: [1-417]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSNCSITRD VFSFFHNKTG NLNYLDNTTQ KPEVFVSPNS TIVSAPTLDS FQALMEKGNF  60
   61 TTLQLAKVGI RMFFSYSVSK YAVLCFSTAI ILNRLTVMSS LRSNSTNIRL PLWSKTLLHL 120
  121 VATLSLVKAL LQILSQFGLM HELHVSDTDF YALSVYLFVA LSDCIEIFIS STTNVPSLIC 180
  181 SDFSIWGLSL NLYIISKMPA GQQHIGDNVE LLGAVFHRLV IHLVELFHIR AYRLCGEVIL 240
  241 NAGFFTAFVT RTYLNGLDFI NICLIHNYFP GFFYISTILL ASIGIFLKAL FTSNPFRSLY 300
  301 SRYKNLEKWW RSNNYNGEEE FNEIALSLCL LLTSNDYKIF KKSDNVKSVD EVAAFSNSYV 360
  361 VSGHLNQLQS TPEDLLSRKE MTTDSQLPGF ARTYLGLFEL VRTIILTYSR LLKNLLW

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [418-484]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKNFESSIDK KPRVGKRKKR DLNKYVTEKN YKKFLYKPDV KELNIESDLR SLELLLPEDD  60
   61 SSKDYFP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [485-616]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRKIDESVSD EEFDSDMESQ LIIDEEKELT HLSSNAVDSD DLEEIAWNIS MWSILNYEMD  60
   61 VHNKVNGPLT RSQYGKRNPQ GVLVDVVIER LLHHTNSRYM YKRLNMKDDD KLEFKFDFAF 120
  121 DSCDEVEEMD LS

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	7.73
Match:
Description:	No description for 1fbvA was found.

Predicted Domain #4

Region A:
Residues: [617-669]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CLICKVNKRN IVTWPCRCLA LCDDCRISLG YKGFATCVSC DSEVKGYSKL NIV

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	7.73
Match:
Description:	No description for 1fbvA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits