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View Structure Prediction Details

Protein: ZDS1
Organism: Saccharomyces cerevisiae
Length: 915 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZDS1.

Description E-value Query
Range
Subject
Range
gi|929925 - gi|929925|gb|AAA74626.1| Ces1p
0.0 [1..915] [1..915]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
2.0E-65 [144..873] [4..732]
gi|8163674 - gi|8163674|gb|AAF73795.1|AF154026_1 surface protein PspC [Streptococcus pneumoniae]
2.0E-50 [314..803] [3..474]
ZAN_MOUSE - Zonadhesin OS=Mus musculus GN=Zan PE=1 SV=1
2.0E-50 [271..830] [545..1121]
gi|16554449, gi|... - gi|16554449|ref|NP_003377.1| zonadhesin isoform 3 [Homo sapiens], gi|12667414|gb|AAK01433.1|AF332977...
1.0E-45 [324..825] [535..1025]

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Predicted Domain #1
Region A:
Residues: [1-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNRDNESML RTTSSDKAIA SQRDKRKSEV LIAAQSLDNE IRSVKNLKRL SIGSMDLLID  60
   61 PELDIKFGGE SSGRRSWSGT TSSSASMPSD TTTVNNTRYS DPTPLENLHG RGNSGIESSN 120
  121 KTKQGNYLGI KKGVHSPSRK LNANVLKKNL LWVPANQHPN VKPDNFLELV QDTLQNIQLS 180
  181 DNGEDNDGNS NENNDIEDNG EDKESQSYEN KENNTINLNR GLSRHGNASL IRRPSTLRRS 240
  241 YTEFDDN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [248-851]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDDDNKGDSA SETVNKVEER ISKIKERPVS LRDITEELTK ISNSAGLTDN DAITLARTLS  60
   61 MAGSYSDKKD QPQPEGHYDE GDIGFSTSQA NTLDDGEFAS NMPINNTMTW PERSSLRRSR 120
  121 FNTYRIRSQE QEKEVEQSVD EMKNDDEERL KLTKNTIKVE IDPHKSPFRQ QDEDSENMSS 180
  181 PGSIGDFQDI YNHYRQSSGE WEQEMGIEKE AEEVPVKVRN DTVEQDLELR EGTTDMVKPS 240
  241 ATDDNKETKR HRRRNGWTWL NNKMSREDDN EENQGDDENE ENVDSQRMEL DNSKKHYISL 300
  301 FNGGEKTEVS NKEEMNNSST STATSQTRQK IEKTFANLFR RKPHHKHDAS SSPSSSPSSS 360
  361 PSIPNNDAVH VRVRKSKKLG NKSGREPVEP IVLRNRPRPH RHHHSRHGSQ KISVKTLKDS 420
  421 QPQQQIPLQP QLEGAIEIEK KEESDSESLP QLQPAVSVSS TKSNSRDREE EEAKKKNKKR 480
  481 SNTTEISNQQ HSKHVQKENT DEQKAQLQAP AQEQVQTSVP VQASAPVQNS APVQTSAPVE 540
  541 ASAQTQAPAA PPLKHTSILP PRKLTFADVK KPDKPNSPVQ FTDSAFGFPL PLLTVSTVIM 600
  601 FDHR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [852-915]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPINVERAIY RLSHLKLSNS KRGLREQVLL SNFMYAYLNL VNHTLYMEQV AHDKEQQQQQ  60
   61 QQQP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.511 a.65.1 Annexin
View Download 0.428 a.16.1 S15/NS1 RNA-binding domain
View Download 0.379 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.412 a.126.1 Serum albumin-like
View Download 0.441 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.373 a.4.1 Homeodomain-like
View Download 0.371 a.17.1 p8-MTCP1
View Download 0.332 a.161.1 beta-catenin-interacting protein ICAT
View Download 0.325 a.112.1 Description not found.
View Download 0.300 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.289 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.289 d.15.7 Immunoglobulin-binding domains
View Download 0.267 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.261 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.248 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.236 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.234 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.233 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.230 a.4.1 Homeodomain-like
View Download 0.224 a.4.1 Homeodomain-like
View Download 0.221 f.30.1 Photosystem I reaction center subunit X, PsaK
View Download 0.212 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.207 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.202 f.15.1 Small-conductance potassium channel

Predicted Domain #4
Region A:
Residues: [460-605]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVPVKVRNDT VEQDLELREG TTDMVKPSAT DDNKETKRHR RRNGWTWLNN KMSREDDNEE  60
   61 NQGDDENEEN VDSQRMELDN SKKHYISLFN GGEKTEVSNK EEMNNSSTST ATSQTRQKIE 120
  121 KTFANLFRRK PHHKHDASSS PSSSPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1w9rA
Description: Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [606-774]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSPSIPNNDA VHVRVRKSKK LGNKSGREPV EPIVLRNRPR PHRHHHSRHG SQKISVKTLK  60
   61 DSQPQQQIPL QPQLEGAIEI EKKEESDSES LPQLQPAVSV SSTKSNSRDR EEEEAKKKNK 120
  121 KRSNTTEISN QQHSKHVQKE NTDEQKAQLQ APAQEQVQTS VPVQASAPV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [775-837]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNSAPVQTSA PVEASAQTQA PAAPPLKHTS ILPPRKLTFA DVKKPDKPNS PVQFTDSAFG  60
   61 FPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [838-915]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLLTVSTVIM FDHRLPINVE RAIYRLSHLK LSNSKRGLRE QVLLSNFMYA YLNLVNHTLY  60
   61 MEQVAHDKEQ QQQQQQQP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.511 N/A N/A a.65.1 Annexin
View Download 0.445 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.441 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.428 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.412 N/A N/A a.126.1 Serum albumin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle