| Protein: | PFK2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 959 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PFK2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..958] | [1..941] |
|
|
0.0 | [1..959] | [1..959] |
|
|
0.0 | [7..959] | [4..944] |
|
|
0.0 | [8..959] | [6..942] |
|
|
0.0 | [1..948] | [1..927] |
|
Region A: Residues: [1-185] |
1 11 21 31 41 51
| | | | | |
1 MTVTTPFVNG TSYCTVTAYS VQSYKAAIDF YTKFLSLENR SSPDENSTLL SNDSISLKIL 60
61 LRPDEKINKN VEAHLKELNS ITKTQDWRSH ATQSLVFNTS DILAVKDTLN AMNAPLQGYP 120
121 TELFPMQLYT LDPLGNVVGV TSTKNAVSTK PTPPPAPEAS AESGLSSKVH SYTDLAYRMK 180
181 TTDTY
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [186-363] |
1 11 21 31 41 51
| | | | | |
1 PSLPKPLNRP QKAIAVMTSG GDAPGMNSNV RAIVRSAIFK GCRAFVVMEG YEGLVRGGPE 60
61 YIKEFHWEDV RGWSAEGGTN IGTARCMEFK KREGRLLGAQ HLIEAGVDAL IVCGGDGSLT 120
121 GADLFRSEWP SLIEELLKTN RISNEQYERM KHLNICGTVG SIDNDMSTTD ATIGAYSA
|
|
Region B: Residues: [483-539] |
1 11 21 31 41 51
| | | | | |
1 QRGGTAVAYD RILATLQGLE AVNAVLESTP DTPSPLIAVN ENKIVRKPLM ESVKLTK
|
| Detection Method: | |
| Confidence: | 635.9897 |
| Match: | 6pfkA_ |
| Description: | ATP-dependent phosphofructokinase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 6-phosphofructokinase activity | 12.7403693686468 | bayes_pls_golite062009 |
| phosphofructokinase activity | 11.7059647240147 | bayes_pls_golite062009 |
| fructose-6-phosphate binding | 9.55959144901554 | bayes_pls_golite062009 |
| fructose binding | 9.55841643584799 | bayes_pls_golite062009 |
| carbohydrate kinase activity | 9.54757838113048 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 3.19280659830412 | bayes_pls_golite062009 |
| kinase activity | 2.85624705588769 | bayes_pls_golite062009 |
| fructose-2,6-bisphosphate 2-phosphatase activity | 2.7198911999025 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 2.67472251964197 | bayes_pls_golite062009 |
| sugar binding | 2.21212411210899 | bayes_pls_golite062009 |
| monosaccharide binding | 2.05358532613083 | bayes_pls_golite062009 |
| transferase activity | 1.97789134877808 | bayes_pls_golite062009 |
| catalytic activity | 1.89212073381079 | bayes_pls_golite062009 |
| protein binding | 1.76136621968843 | bayes_pls_golite062009 |
| binding | 1.57437723650762 | bayes_pls_golite062009 |
| carbohydrate binding | 0.97067862054315 | bayes_pls_golite062009 |
| hydrolase activity | 0.276140444059183 | bayes_pls_golite062009 |
|
Region A: Residues: [364-482] |
1 11 21 31 41 51
| | | | | |
1 LDRICKAIDY VEATANSHSR AFVVEVMGRN CGWLALLAGI ATSADYIFIP EKPATSSEWQ 60
61 DQMCDIVSKH RSRGKRTTIV VVAEGAIAAD LTPISPSDVH KVLVDRLGLD TRITTLGHV
|
|
Region B: Residues: [540-548] |
1 11 21 31 41 51
| | | | | |
1 AVAEAIQAK
|
| Detection Method: | |
| Confidence: | 635.9897 |
| Match: | 6pfkA_ |
| Description: | ATP-dependent phosphofructokinase |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 6-phosphofructokinase activity | 12.7403693686468 | bayes_pls_golite062009 |
| phosphofructokinase activity | 11.7059647240147 | bayes_pls_golite062009 |
| fructose-6-phosphate binding | 9.55959144901554 | bayes_pls_golite062009 |
| fructose binding | 9.55841643584799 | bayes_pls_golite062009 |
| carbohydrate kinase activity | 9.54757838113048 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 3.19280659830412 | bayes_pls_golite062009 |
| kinase activity | 2.85624705588769 | bayes_pls_golite062009 |
| fructose-2,6-bisphosphate 2-phosphatase activity | 2.7198911999025 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 2.67472251964197 | bayes_pls_golite062009 |
| sugar binding | 2.21212411210899 | bayes_pls_golite062009 |
| monosaccharide binding | 2.05358532613083 | bayes_pls_golite062009 |
| transferase activity | 1.97789134877808 | bayes_pls_golite062009 |
| catalytic activity | 1.89212073381079 | bayes_pls_golite062009 |
| protein binding | 1.76136621968843 | bayes_pls_golite062009 |
| binding | 1.57437723650762 | bayes_pls_golite062009 |
| carbohydrate binding | 0.97067862054315 | bayes_pls_golite062009 |
| hydrolase activity | 0.276140444059183 | bayes_pls_golite062009 |
|
Region A: Residues: [549-827] |
1 11 21 31 41 51
| | | | | |
1 DFKRAMSLRD TEFIEHLNNF MAINSADHNE PKLPKDKRLK IAIVNVGAPA GGINSAVYSM 60
61 ATYCMSQGHR PYAIYNGWSG LARHESVRSL NWKDMLGWQS RGGSEIGTNR VTPEEADLGM 120
121 IAYYFQKYEF DGLIIVGGFE AFESLHQLER ARESYPAFRI PMVLIPATLS NNVPGTEYSL 180
181 GSDTALNALM EYCDVVKQSA SSTRGRAFVV DCQGGNSGYL ATYASLAVGA QVSYVPEEGI 240
241 SLEQLSEDIE YLAQSFEKAE GRGRFGKLIL KSTNASKAL
|
| Detection Method: | |
| Confidence: | 112.08661 |
| Match: | 1kzhA_ |
| Description: | Pyrophosphate-dependent phosphofructokinase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [828-959] |
1 11 21 31 41 51
| | | | | |
1 SATKLAEVIT AEADGRFDAK PAYPGHVQQG GLPSPIDRTR ATRMAIKAVG FIKDNQAAIA 60
61 EARAAEENFN ADDKTISDTA AVVGVKGSHV VYNSIRQLYD YETEVSMRMP KVIHWQATRL 120
121 IADHLVGRKR VD
|
| Detection Method: | |
| Confidence: | 12.5 |
| Match: | 1pfkA |
| Description: | ATP-dependent phosphofructokinase |
Matching Structure (courtesy of the PDB): |
|
