| Protein: | GCV2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1034 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GCV2.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1034] | [1..1034] |
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0.0 | [1..1034] | [1..1034] |
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0.0 | [5..1032] | [3..1030] |
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0.0 | [5..1033] | [3..1040] |
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0.0 | [5..1034] | [3..1034] |
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0.0 | [5..1034] | [3..1031] |
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Region A: Residues: [1-111] |
1 11 21 31 41 51
| | | | | |
1 MLRTRVTALL CRATVRSSTN YVSLARTRSF HSQSILLKTA ATDITSTQYS RIFNPDLKNI 60
61 DRPLDTFARR HLGPSPSDVK KMLKTMGYSD LNAFIEELVP PNILKRRPLK L
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| glycine dehydrogenase (decarboxylating) activity | 8.00572280567771 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor | 8.00572280567771 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH2 group of donors | 3.14486270422678 | bayes_pls_golite062009 |
| catalytic activity | 2.29878871754893 | bayes_pls_golite062009 |
| transferase activity | 1.44093490824786 | bayes_pls_golite062009 |
| transferase activity, transferring nitrogenous groups | 1.28316822767388 | bayes_pls_golite062009 |
| transaminase activity | 1.24990480711889 | bayes_pls_golite062009 |
| methyltransferase activity | 0.681623261233707 | bayes_pls_golite062009 |
| L-aspartate:2-oxoglutarate aminotransferase activity | 0.619695949258279 | bayes_pls_golite062009 |
| transferase activity, transferring one-carbon groups | 0.60304280865376 | bayes_pls_golite062009 |
| glycine hydroxymethyltransferase activity | 0.271623203801431 | bayes_pls_golite062009 |
| O-phospho-L-serine:2-oxoglutarate aminotransferase activity | 0.234399054481664 | bayes_pls_golite062009 |
| pyridoxal phosphate binding | 0.16957228630576 | bayes_pls_golite062009 |
| vitamin B6 binding | 0.16957228630576 | bayes_pls_golite062009 |
|
Region A: Residues: [112-146] |
1 11 21 31 41 51
| | | | | |
1 EAPSKGFCEQ EMLQHLEKIA NKNHYKVKNF IGKGY
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Region B: Residues: [426-539] |
1 11 21 31 41 51
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1 SRRIFSLTSI LANAIENDSC PHELINKTWF DTLTIKLGNG ISSEQLLDKA LKEFNINLFA 60
61 VDTTTISLAL DETTTKADVE NLLKVFDIEN SSQFLSEDYS NSFPREFQRT DEIL
|
| Detection Method: | |
| Confidence: | 65.522879 |
| Match: | 1jf9A_ |
| Description: | NifS-like protein/selenocysteine lyase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| glycine dehydrogenase (decarboxylating) activity | 8.00572280567771 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor | 8.00572280567771 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on the CH-NH2 group of donors | 3.14486270422678 | bayes_pls_golite062009 |
| catalytic activity | 2.29878871754893 | bayes_pls_golite062009 |
| transferase activity | 1.44093490824786 | bayes_pls_golite062009 |
| transferase activity, transferring nitrogenous groups | 1.28316822767388 | bayes_pls_golite062009 |
| transaminase activity | 1.24990480711889 | bayes_pls_golite062009 |
| methyltransferase activity | 0.681623261233707 | bayes_pls_golite062009 |
| L-aspartate:2-oxoglutarate aminotransferase activity | 0.619695949258279 | bayes_pls_golite062009 |
| transferase activity, transferring one-carbon groups | 0.60304280865376 | bayes_pls_golite062009 |
| glycine hydroxymethyltransferase activity | 0.271623203801431 | bayes_pls_golite062009 |
| O-phospho-L-serine:2-oxoglutarate aminotransferase activity | 0.234399054481664 | bayes_pls_golite062009 |
| pyridoxal phosphate binding | 0.16957228630576 | bayes_pls_golite062009 |
| vitamin B6 binding | 0.16957228630576 | bayes_pls_golite062009 |
|
Region A: Residues: [147-425] |
1 11 21 31 41 51
| | | | | |
1 YGTILPPVIQ RNLLESPEWY TSYTPYQPEI SQGRLEALLN FQTVVSDLTG LPVANASLLD 60
61 EGTAAGEAML LSFNISRKKK LKYVIDKKLH QQTKSVLHTR AKPFNIEIIE VDCSDIKKAV 120
121 DVLKNPDVSG CLVQYPATDG SILPPDSMKQ LSDALHSHKS LLSVASDLMA LTLLKPPAHY 180
181 GADIVLGSSQ RFGVPMGYGG PHAAFFAVID KLNRKIPGRI VGISKDRLGK TALRLALQTR 240
241 EQHIKRDKAT SNICTAQALL ANVASSYCVY HGPKGLQNI
|
| Detection Method: | |
| Confidence: | 65.522879 |
| Match: | 1jf9A_ |
| Description: | NifS-like protein/selenocysteine lyase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [540-850] |
1 11 21 31 41 51
| | | | | |
1 RNEVFHMHHS ETAMLRYLHR LQSRDLSLAN SMIPLGSCTM KLNSTVEMMP ITWPQFSNIH 60
61 PFQPSNQVQG YKELITSLEK DLCSITGFDG ISLQPNSGAQ GEYTGLRVIR SYLESKGENH 120
121 RNVCLIPVSA HGTNPASAAM AGLKVVPVNC LQDGSLDLVD LKNKAEQHSK ELAAVMITYP 180
181 STYGLFEPGI QHAIDIVHSF GGQVYLDGAN MNAQVGLTSP GDLGADVCHL NLHKTFSIPH 240
241 GGGGPAGAPI CVKSHLIPHL PKHDVVDMIT GIGGSKSIDS VSSAPYGNAL VLPISYAYIK 300
301 MMGNEGLPFS S
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|
Region B: Residues: [882-894] |
1 11 21 31 41 51
| | | | | |
1 CAHEFIVDLR EYK
|
| Detection Method: | |
| Confidence: | 63.0 |
| Match: | 1qgnA_ |
| Description: | Cystathionine gamma-synthase, CGS |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [851-881] |
1 11 21 31 41 51
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1 VIAMLNSNYM MTRLKDHYKI LFVNEMSTLK H
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Region B: Residues: [895-1034] |
1 11 21 31 41 51
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1 AKGVEAIDVA KRLQDYGFHA PTLAFPVPGT LMIEPTESEN LEELDRFCDA MISIKEEINA 60
61 LVAGQPKGQI LKNAPHSLED LITSSNWDTR GYTREEAAYP LPFLRYNKFW PTVARLDDTY 120
121 GDMNLICTCP SVEEIANETE
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| Detection Method: | |
| Confidence: | 63.0 |
| Match: | 1qgnA_ |
| Description: | Cystathionine gamma-synthase, CGS |
| Matching Structure (courtesy of the PDB): |
|
