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View Structure Prediction Details

Protein: HOT1
Organism: Saccharomyces cerevisiae
Length: 719 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HOT1.

Description E-value Query
Range
Subject
Range
GCR1 - Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and fu...
GCR1_YEAST - Glycolytic genes transcriptional activator GCR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...
476.0 [0..307] [683..325]
HOT1_CANGA - High-osmolarity-induced transcription protein 1 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JC...
HOT1_CANGA - High-osmolarity-induced transcription protein 1 OS=Candida glabrata GN=HOT1 PE=3 SV=1
179.0 [0..157] [719..59]
HOT1_KLULA - High-osmolarity-induced transcription protein 1 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359...
HOT1_KLULA - High-osmolarity-induced transcription protein 1 OS=Kluyveromyces lactis GN=HOT1 PE=3 SV=1
149.0 [0..146] [719..163]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGMGIAILC IVRTKIYRIT ISFDYSTLMS PFFLFLMMPT TLKDGYRMNS QVNEDAIGIN  60
   61 LDLSLPTHIS PTTGSESASG SNASTLRNDG NALDGGLLRT SAAISAPTGT SQPTETIGEK 120
  121 LSNEERVNSN VSASNSTTAG TGRMLSQSLT NDSP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNEISTDQLK IFQRMDEMSA RMIEMEESFN KLSNKIAEQN TMVLNLKQDN YKVMNKLNIL  60
   61 LKLVAQPSAR PSTNNAQNKL AIELLNSISA VSSAYLQKMQ NNGSGRQHTA DLCTGDSNTH 120
  121 SGINQHRTTN GTIDVNTNTA QLNNQFSNAL NTILPDQQHN RNNVSQNINQ SLPNRQLGPV 180
  181 INTQANQNQS QVLIHNTNTH QQVNRSPISF PNASTDKPFK LNPNGIKRRR RNTQSNNNAS 240
  241 TNDHASAAQK PISALSPLTN SHNSTTSMNY TNSSIHSGVT SASNSFHDLN SLNNFGTTTA 300
  301 LSLPSLALDN ASFPPNQNVI PPIINNTQQP LSFSQLINQD STTSELLPSG KSGVNTNIVN 360
  361 RNRASTLPSY PKPMTVKSNV DDDGYQEDDD DDGDDEGDGR DNEEDSTAEE DEVDDEIETD 420
  421 MKNASINKRR RSLH

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 9.25
Match:
Description: No description for 1i3qA was found.

Predicted Domain #3
Region A:
Residues: [589-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKKSNSLNGR RKLHGESATK PNINSDLHYR ILKAPTDVKT IWEEYDTGIR GKPSIKHLEA  60
   61 KYGNKWRLNK NKKTFSRRKR LYKFILNGME RGKTAQEMIE TLENKRLYKD DEDGEVKKRT 120
  121 IGWLQESLAG I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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