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View Structure Prediction Details

Protein: NUP53
Organism: Saccharomyces cerevisiae
Length: 475 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP53.

Description E-value Query
Range
Subject
Range
ASM4 - Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p
NUP59_YEAST - Nucleoporin ASM4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ASM4 PE=1 SV=1
563.0 [0..1] [475..1]
gi|45188145, gi|... - gi|45188145|ref|NP_984368.1| ADR272Wp [Ashbya gossypii ATCC 10895], gi|44982962|gb|AAS52192.1| ADR27...
gi|44982962 - gi|44982962|gb|AAS52192.1| ADR272Wp [Ashbya gossypii ATCC 10895]
262.0 [0..5] [475..7]
gi|49644544 - gi|49644544|emb|CAG98116.1| KLLA0F07227p [Kluyveromyces lactis]
gi|50310771, gi|... - gi|50310771|ref|XP_455408.1| unnamed protein product [Kluyveromyces lactis], gi|49644544|emb|CAG9811...
246.0 [0..70] [475..44]
gi|49528397, gi|... - gi|50293345|ref|XP_449084.1| unnamed protein product [Candida glabrata], gi|49528397|emb|CAG62054.1|...
gi|49528397 - gi|49528397|emb|CAG62054.1| unnamed protein product [Candida glabrata]
210.0 [0..12] [475..9]
NUP40_SCHPO - Nucleoporin nup40 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nup40 PE=1 SV=1
nup40 - nucleoporin Nup40
198.0 [0..198] [374..119]
gi|50427331, gi|... - gi|50427331|ref|XP_462278.1| hypothetical protein DEHA0G18117g [Debaryomyces hansenii CBS767], gi|49...
gi|49657948 - gi|49657948|emb|CAG90780.1| DEHA2G17006p [Debaryomyces hansenii]
139.0 [0..76] [475..41]
gi|49648465 - gi|49648465|emb|CAG80785.1| YALI0D08954p [Yarrowia lipolytica]
gi|50550249, gi|... - gi|50550249|ref|XP_502597.1| YALI0D08954p [Yarrowia lipolytica], gi|49648465|emb|CAG80785.1| YALI0D0...
86.0 [0..200] [425..239]

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Predicted Domain #1
Region A:
Residues: [1-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADLQKQENS SRFTNVSVIA PESQGQHEQQ KQQEQLEQQK QPTGLLKGLN GFPSAPQPLF  60
   61 MEDPPSTVSG ELNDNPAWFN NPRKRAIPNS IIKRSNGQSL SPVRSDSADV PAFSNSNGFN 120
  121 NVTFGSKKDP RILKNVSPND NNSANNNAHS SDLGTVVFDS NEAPPKTSLA DWQKEDGIFS 180
  181 SKTDNIEDPN LSSNITFDGK PTATPSPFRP LEKTSRILNF FDKNTKTTPN TASSEASAGS 240
  241 KEGASTNWDD HAIIIFGYPE TIANSIILHF ANFGEILEDF RVIKDFKKLN SKNMSKSPSL 300
  301 TAQKYPIYTG DGWVKLTYKS ELSKSRALQE NGIIMNGTLI GCVSYSPAAL KQLASLKKSE 360
  361 EIINNKTSSQ TSLSSKDLS

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 12.52
Match:
Description: No description for 1i3qA was found.

Predicted Domain #2
Region A:
Residues: [380-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYRKTEGIFE KAKAKAVTSK VRNAEFKVSK NSTSFKNPRR LEIKDGRSLF LRNRGKIHSG  60
   61 VLSSIESDLK KREQASKSKK SWLNRLNNWL FGWNDL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.656 d.20.1 UBC-like
View Download 0.548 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.548 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.529 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.429 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.424 a.29.14 Description not found.
View Download 0.386 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.373 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.356 a.118.11 Cytochrome c oxidase subunit E


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle