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View Structure Prediction Details

Protein: YPK2
Organism: Saccharomyces cerevisiae
Length: 677 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPK2.

Description E-value Query
Range
Subject
Range
YPK2_YEAST - Serine/threonine-protein kinase YPK2/YKR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
YPK2 - Protein kinase with similarity to serine/threonine protein kinase Ypk1p; functionally redundant with...
0.0 [1..677] [1..677]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [1..677] [1..677]
KPCB_RABIT - Protein kinase C beta type OS=Oryctolagus cuniculus GN=PRKCB PE=2 SV=3
0.0 [193..666] [180..668]
PRKCB1 - protein kinase C, beta 1
0.0 [193..666] [180..668]
gi|15072452 - gi|15072452|gb|AAK40343.1| protein kinase 1 [Cryphonectria parasitica]
0.0 [43..663] [13..617]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [193..666] [180..668]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSWRISKFK LGRSKEDDGS SEDENEKSWG NGLFHFHHGE KHHDGSPKNH NHEHEHHIRK  60
   61 INTNETLPSS LSSPKLRNDA SFKNPSGIGN DNSKASERKA SQSSTETQGP SSESGLMTVK 120
  121 VYSGKDFTLP FPITSNSTIL QKLLSSGILT S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [152-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNDASEVAA IMRQLPRYKR VDQDSAGEGL IDRAFATKFI PSSILLPGST NSSPLLYFTI  60
   61 EFDNSITTIS PDMGTMEQPV FNKISTFDVT RKLRFLKIDV FARIPSLLLP SKNWQQEIGE 120
  121 QDEVLKEIL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1jnuA_
Description: Photoreceptor phy3 flavin-binding domain, lov2
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [281-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKINTNQDIH LDSFHLPLNL KIDSAAQIRL YNHHWISLER GYGKLNITVD YKPSK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [387-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THTLAERTVL ARVDCPFIVP L

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [423-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FINGGELFYH LQHEGRFSLA RSRFYIAELL CALDSLHKLD VIYRDLKPEN ILLDYQGHIA  60
   61 LCDFGLCKLN MKDNDKTDTF CGTPEYLAPE ILLGQGYTKT VDWWTLGILL YEMMTGLPPY 120
  121 YDENVPVMYK KILQQPLLFP DGFDPAAKDL LIGLLSRDPS RRLGVNGTDE IRNHPFFKDI 180
  181 SWKKLLLKGY IPPYKPIVKS EI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 856.9794
Match: 1atpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [336-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKPLSIDDFD LLKVIGKGSF GKVMQVRKKD TQKIYALKAL RKAYIVSKCE V

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [408-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFSFQSPEKL YLVLA

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [625-677]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTANFDQEFT KEKPIDSVVD EYLSASIQKQ FGGWTYIGDE QLGDSPSQGR SIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 856.9794
Match: 1atpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle