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View Structure Prediction Details

Protein: YPK2
Organism: Saccharomyces cerevisiae
Length: 677 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPK2.

Description E-value Query
Range
Subject
Range
YPK2_YEAST - Serine/threonine-protein kinase YPK2/YKR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
YPK2 - Protein kinase with similarity to serine/threonine protein kinase Ypk1p; functionally redundant with...
0.0 [1..677] [1..677]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [1..677] [1..677]
KPCB_RABIT - Protein kinase C beta type OS=Oryctolagus cuniculus GN=PRKCB PE=2 SV=3
0.0 [193..666] [180..668]
PRKCB1 - protein kinase C, beta 1
0.0 [193..666] [180..668]
gi|15072452 - gi|15072452|gb|AAK40343.1| protein kinase 1 [Cryphonectria parasitica]
0.0 [43..663] [13..617]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [193..666] [180..668]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSWRISKFK LGRSKEDDGS SEDENEKSWG NGLFHFHHGE KHHDGSPKNH NHEHEHHIRK  60
   61 INTNETLPSS LSSPKLRNDA SFKNPSGIGN DNSKASERKA SQSSTETQGP SSESGLMTVK 120
  121 VYSGKDFTLP FPITSNSTIL QKLLSSGILT S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [152-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSNDASEVAA IMRQLPRYKR VDQDSAGEGL IDRAFATKFI PSSILLPGST NSSPLLYFTI  60
   61 EFDNSITTIS PDMGTMEQPV FNKISTFDVT RKLRFLKIDV FARIPSLLLP SKNWQQEIGE 120
  121 QDEVLKEIL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1jnuA_
Description: Photoreceptor phy3 flavin-binding domain, lov2
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [281-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKINTNQDIH LDSFHLPLNL KIDSAAQIRL YNHHWISLER GYGKLNITVD YKPSK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [387-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THTLAERTVL ARVDCPFIVP L

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [423-624]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FINGGELFYH LQHEGRFSLA RSRFYIAELL CALDSLHKLD VIYRDLKPEN ILLDYQGHIA  60
   61 LCDFGLCKLN MKDNDKTDTF CGTPEYLAPE ILLGQGYTKT VDWWTLGILL YEMMTGLPPY 120
  121 YDENVPVMYK KILQQPLLFP DGFDPAAKDL LIGLLSRDPS RRLGVNGTDE IRNHPFFKDI 180
  181 SWKKLLLKGY IPPYKPIVKS EI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 856.9794
Match: 1atpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [336-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKPLSIDDFD LLKVIGKGSF GKVMQVRKKD TQKIYALKAL RKAYIVSKCE V

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [408-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFSFQSPEKL YLVLA

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [625-677]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTANFDQEFT KEKPIDSVVD EYLSASIQKQ FGGWTYIGDE QLGDSPSQGR SIS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 856.9794
Match: 1atpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle