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View Structure Prediction Details

Protein: NUP116
Organism: Saccharomyces cerevisiae
Length: 1113 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP116.

Description E-value Query
Range
Subject
Range
NUP116 - Subunit of the Nup82 subcomplex of the nuclear pore complex; localized to both sides of the pore; co...
NU116_YEAST - Nucleoporin NUP116/NSP116 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP116 PE=1 SV...
0.0 [1..1113] [1..1113]
gi|18032249 - gi|18032249|gb|AAL56659.1|AF231130_1 NUP196 nucleoporin [Homo sapiens]
2.0E-88 [225..1108] [5..862]
NU98A_ARATH - Nuclear pore complex protein NUP98A OS=Arabidopsis thaliana GN=NUP98A PE=1 SV=1
2.0E-81 [64..1108] [2..1026]
SPBPJ4664.02 - glycoprotein
YHU2_SCHPO - Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 OS=Schizosaccharomyces pombe (str...
4.0E-71 [6..947] [1406..2356]
gi|3845093, gi|1... - gi|3845093|gb|AAC71809.1| erythrocyte membrane protein 3 [Plasmodium falciparum 3D7], gi|16804919|re...
gi|7494164 - pir||D71623 erythrocyte membrane protein PfEMP3 PFB0095c - malaria parasite (Plasmodium falciparum)
3.0E-68 [13..978] [1331..2310]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-67 [692..1108] [9..406]

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Predicted Domain #1
Region A:
Residues: [1-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGVSRGAFP SATTQPFGST GSTFGGQQQQ QQPVANTSAF GLSQQTNTTQ APAFGNFGNQ  60
   61 TSNSPFGMSG STTANGTPFG QSQLTNNNAS GSIFGGMGNN TALSAGSASV VPNSTAGTSI 120
  121 KPFTTFEEKD PTTGVINVFQ SITCMPEYRN FSFEELRFQD YQAGRKFGTS QNGTGTTFNN 180
  181 PQGTTNTGFG IMGNNNSTTS ATTGGLFGQK PATGMFGTGT GSGGGFGSGA TNSTGLFGSS 240
  241 TNLSGNSAFG ANKPATSGGL FGNTTNNPTN GTNNTGLFGQ QNSNTNGGLF GQQQNSFGAN 300
  301 NVSNGGAFGQ VNRGAFPQQQ TQQGSGGIFG QSNANANGGA FGQQQGTGAL FGAKPASGGL 360
  361 FGQSAGSKAF GMNTNPTGTT GGLFGQTNQQ QSGGGLFGQQ QNSNAGGLFG QNNQSQNQSG 420
  421 LFGQQNSSNA FGQPQQQGGL FGSKPAGGLF GQQQGASTFA SGNAQNNSIF GQNNQQQQST 480
  481 GGLFGQQNNQ SQSQPGGLFG QTNQNNNQPF 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [511-623]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQNGLQQPQQ NNSLFGAKPT GFGNTSLFSN STTNQSNGIS GNNLQQQSGG LFQNKQQPAS  60
   61 GGLFGSKPSN TVGGGLFGNN QVANQNNPAS TSGGLFGSKP ATGSLFGGTN STA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [624-1006]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNASSGGIFG SNNASNTAAT TNSTGLFGNK PVGAGASTSA GGLFGNNNNS SLNNSNGSTG  60
   61 LFGSNNTSQS TNAGGLFQNN TSTNTSGGGL FSQPSQSMAQ SQNALQQQQQ QQRLQIQNNN 120
  121 PYGTNELFSK ATVTNTVSYP IQPSATKIKA DERKKASLTN AYKMIPKTLF TAKLKTNNSV 180
  181 MDKAQIKVDP KLSISIDKKN NQIAISNQQE ENLDESILKA SELLFNPDKR SFKNLINNRK 240
  241 MLIASEEKNN GSQNNDMNFK SKSEEQETIL GKPKMDEKET ANGGERMVLS SKNDGEDSAT 300
  301 KHHSRNMDEE NKENVADLQK QEYSEDDKKA VFADVAEKDA SFINENYYIS PSLDTLSSYS 360
  361 LLQLRKVPHL VVGHKSYGKI EFL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1007-1113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPVDLAGIPL TSLGGVIITF EPKTCIIYAN LPNRPKRGEG INVRARITCF NCYPVDKSTR  60
   61 KPIKDPNHQL VKRHIERLKK NPNSKFESYD ADSGTYVFIV NHAAEQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [683-781]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLFGSNNTSQ STNAGGLFQN NTSTNTSGGG LFSQPSQSMA QSQNALQQQQ QQQRLQIQNN  60
   61 NPYGTNELFS KATVTNTVSY PIQPSATKIK ADERKKASL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [782-967]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNAYKMIPKT LFTAKLKTNN SVMDKAQIKV DPKLSISIDK KNNQIAISNQ QEENLDESIL  60
   61 KASELLFNPD KRSFKNLINN RKMLIASEEK NNGSQNNDMN FKSKSEEQET ILGKPKMDEK 120
  121 ETANGGERMV LSSKNDGEDS ATKHHSRNMD EENKENVADL QKQEYSEDDK KAVFADVAEK 180
  181 DASFIN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [968-1113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENYYISPSLD TLSSYSLLQL RKVPHLVVGH KSYGKIEFLE PVDLAGIPLT SLGGVIITFE  60
   61 PKTCIIYANL PNRPKRGEGI NVRARITCFN CYPVDKSTRK PIKDPNHQLV KRHIERLKKN 120
  121 PNSKFESYDA DSGTYVFIVN HAAEQT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.154902
Match: 2aivA
Description: Multiple conformations in the ligand-binding site of the yeast nuclear pore targeting domain of NUP116P
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle