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View Structure Prediction Details

Protein: YML096W
Organism: Saccharomyces cerevisiae
Length: 525 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YML096W.

Description E-value Query
Range		 Subject
Range
ASNS_TRIVS - Asparagine synthetase [glutamine-hydrolyzing] OS=Triphysaria versicolor GN=AS PE=2 SV=3
 0.0 [1..522] [1..481]
gi|3859536 - gi|3859536|gb|AAC72837.1| asparagine synthetase [Arabidopsis thaliana]
 0.0 [1..522] [1..481]
ASNS_ASPOF - Asparagine synthetase [glutamine-hydrolyzing] OS=Asparagus officinalis PE=2 SV=2
 0.0 [1..522] [1..481]
gi|6049843 - gi|6049843|gb|AAF02776.1|AF190729_1 asparagine synthetase [Helianthus annuus]
 0.0 [1..523] [1..482]
gi|13925886 - gi|13925886|gb|AAK49456.1|AF307145_1 glutamine-dependent asparagine synthetase 1 [Hordeum vulgare su...
 0.0 [1..522] [1..481]
ASNS_SANAU - Asparagine synthetase [glutamine-hydrolyzing] OS=Sandersonia aurantiaca GN=AND1 PE=2 SV=3
 0.0 [1..522] [1..481]
ASNS1_LOTJA - Asparagine synthetase [glutamine-hydrolyzing] 1 OS=Lotus japonicus GN=AS1 PE=2 SV=2
 0.0 [1..522] [1..481]

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Predicted Domain #1
Region A:
Residues: [1-203] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGILLHYCP NNNYLNDELI EFPEGTEFGD TTCTNESSIF NKIIPYIAAR GPNYSSLRAV  60
   61 KAYRISWFSS VLSLRQPFTK QSINVDDRYF LQFNGELYNK EISQGDNDSL YIASMLQNLK 120
  121 EGMGVIDVIK SLEGEYAYTI YDVNSSKLYF GRDPIGRRSL SYSVTPDNEL YVASVTGSAG 180
  181 SFQDCIGGVI YEYDTRTKLL NSN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 228.457575
Match: 1ct9A_
Description: Asparagine synthetase B, C-terminal domain; Asparagine synthetase B, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity 2.99185607397345 bayes_pls_golite062009
nucleic acid binding 1.14663773925119 bayes_pls_golite062009
DNA binding 0.992954560970173 bayes_pls_golite062009
catalytic activity 0.828867994386867 bayes_pls_golite062009
binding 0.752095595503409 bayes_pls_golite062009
endopeptidase activity 0.0940838340168359 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [204-525] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRSHLPYEVT SEIDLNFTSL SEVSKNLYAV LRDSVKKRVE SIHPRHIENS PIAVLFSGGI  60
   61 DCSVIVALIC EVLQENDYKC GKPVIELLNV SFENPRTGLF PSDTPDRKLS INSAKTLQNL 120
  121 YPNVDIKLVE VDVPYDEYLK WKPFVINLMY PKQTEMDLSI AIAFFFASRG RGFLTSLNGE 180
  181 RTPYQRHGIV LFSGLGADEL YGGYHKFANK PPHELVEELT RQINNIYDRN LNRDDKVIAH 240
  241 NGVEVRYPFL DEYVIKLSTA EIPINFKVNK LILRKVASQY LKLDGISSEP KRAIQFGAKS 300
  301 AKMTKDGNKH GTDLLKENRN CS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 228.457575
Match: 1ct9A_
Description: Asparagine synthetase B, C-terminal domain; Asparagine synthetase B, N-terminal domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle