YRC Public Data Repository - Protein Structure Prediction

Protein:	VMA6
Organism:	Saccharomyces cerevisiae
Length:	345 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VMA6.

Description	E-value	Query Range	Subject Range
VhaAC39-PA - The gene Vacuolar H<sup>+</sup>-ATPase C39 subunit is referred to in FlyBase by the symbol Dmel\VhaA... gi\|194131180, gi... - gi\|195340927\|ref\|XP_002037064.1\| GM12314 [Drosophila sechellia], gi\|194131180\|gb\|EDW53223.1\| GM12314... gi\|220956386 - gi\|220956386\|gb\|ACL90736.1\| VhaAC39-PA [synthetic construct]	0.0	[3..345]	[5..350]
VA0D_MANSE - V-type proton ATPase subunit d OS=Manduca sexta PE=2 SV=1	0.0	[1..345]	[1..348]
VA0D1_MOUSE - V-type proton ATPase subunit d 1 OS=Mus musculus GN=Atp6v0d1 PE=1 SV=2 gi\|149038021, gi... - gi\|58865424\|ref\|NP_001011927.1\| ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 [Rattus norv... tr\|G3HZM3\|G3HZM3... - V-type proton ATPase subunit d 1 OS=Cricetulus griseus GN=I79_016530 PE=4 SV=1	0.0	[3..345]	[6..351]
VMA6 - Subunit d of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an elect... gi\|151940962 - gi\|151940962\|gb\|EDN59344.1\| V-ATPase V0 sector subunit d [Saccharomyces cerevisiae YJM789] VA0D_YEAST - V-type proton ATPase subunit d OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VMA6 PE=1... gi\|190405482 - gi\|190405482\|gb\|EDV08749.1\| vacuolar ATP synthase subunit d [Saccharomyces cerevisiae RM11-1a] gi\|207342661 - gi\|207342661\|gb\|EDZ70361.1\| YLR447Cp-like protein [Saccharomyces cerevisiae AWRI1631]	0.0	[1..345]	[1..345]
vha-16 - vaculolar ATPase status:Confirmed UniProt:Q95YD5 protein_id:AAK85455.2	0.0	[1..344]	[1..347]
VA0D_DICDI - Vacuolar ATP synthase subunit d - Dictyostelium discoideum (Slime mold)	0.0	[4..345]	[13..356]
VA0D2_ARATH - V-type proton ATPase subunit d2 OS=Arabidopsis thaliana GN=VHA-d2 PE=2 SV=1	0.0	[2..343]	[5..348]

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Predicted Domain #1

Region A:
Residues: [1-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGVYFNIDN GFIEGVVRGY RNGLLSNNQY INLTQCDTLE DLKLQLSSTD YGNFLSSVSS  60
   61 ESLTTSLIQE YASSKLYHEF NYIRDQSSGS TRKFMDYITY GYMIDNVALM ITGTIHDRDK 120
  121 GEILQRCHPL GWFDTLPTLS VATDLESLYE TVLVDTPLAP YFKNCFDTAE ELDDMNIEII 180
  181 RNKLYKAYLE DFYNFVTEEI PEPAKECMQT LLGFEADRRS INIALNSLQS SDIDPDLKSD 240
  241 LLPNIGKLYP LATFHLAQAQ DFEGVRAALA NVYEYRGFLE TGNLEDHFYQ LEMELCRDAF 300
  301 TQQFAISTVW AWMKSKEQEV RNITWIAECI AQNQRERINN YISVY

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	8.39
Match:	1b89A
Description:	Clathrin heavy chain proximal leg segment
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits