YRC Public Data Repository - Protein Structure Prediction

Protein:	RPN13
Organism:	Saccharomyces cerevisiae
Length:	156 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN13.

Description	E-value	Query Range	Subject Range
RPN13 - Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for t... RPN13_YEAST - 26S proteasome regulatory subunit RPN13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=... gi\|151940938 - gi\|151940938\|gb\|EDN59320.1\| regulatory particle non-ATPase [Saccharomyces cerevisiae YJM789]	7.0E-52	[1..156]	[1..156]
ADRM1_CHICK - Proteasomal ubiquitin receptor ADRM1 OS=Gallus gallus GN=ADRM1 PE=2 SV=1	2.0E-46	[2..132]	[18..131]
gi\|148224798, gi... - gi\|6174842\|dbj\|BAA86033.1\| oocyte membrane protein [Xenopus laevis], gi\|148224798\|ref\|NP_001081367.1...	1.0E-45	[2..132]	[17..130]
gi\|124000251, gi... - gi\|61363711\|gb\|AAX42432.1\| adhesion regulating molecule 1 [synthetic construct], gi\|124000251\|gb\|ABM... ADRM1 - adhesion regulating molecule 1	2.0E-45	[2..132]	[18..131]
ADRM1_MOUSE - Proteasomal ubiquitin receptor ADRM1 OS=Mus musculus GN=Adrm1 PE=1 SV=2	3.0E-45	[2..132]	[18..131]
ADRM1_RAT, ADRM_RAT - (Q9JMB5) Adhesion regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110), Adhe...	9.0E-45	[2..132]	[18..131]
CG6789-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6789 (CG6789, FBgn0029745). It is a protein... gi\|220957910, gi... - gi\|220957910\|gb\|ACL91498.1\| CG6789-PA [synthetic construct], gi\|220950914\|gb\|ACL88000.1\| CG6789-PA [...	1.0E-42	[2..151]	[4..137]
SPCC16A11.16c - ARM1 family ADRM1_SCHPO - Probable proteasomal ubiquitin receptor ADRM1 homolog OS=Schizosaccharomyces pombe (strain 972 / ATC...	6.0E-42	[7..143]	[20..157]
gi\|27363336, gi\|... - gi\|27363336\|gb\|AAO11587.1\| At2g26590/T9J22.26 [Arabidopsis thaliana], gi\|13926227\|gb\|AAK49589.1\|AF37...	6.0E-38	[3..139]	[10..128]

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Predicted Domain #1

Region A:
Residues: [1-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMSSTVIKF RAGVCEYNED SRLCTPIPVQ GEIEIKPNEE EELGFWDFEW RPTEKPVGRE  60
   61 LDPISLILIP GETMWVPIKS SKSGRIFALV FSSNERYFFW LQEKNSGNLP LNELSAKDKE 120
  121 IYNKMIGVLN NSSESDEEES NDEKQKAQDV DVSMQD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
hydrolase activity	2.56405396848915	bayes_pls_golite062009
binding	1.92972815841164	bayes_pls_golite062009
protein binding	1.26119545864643	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: