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View Structure Prediction Details

Protein: CSR1
Organism: Saccharomyces cerevisiae
Length: 408 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CSR1.

Description E-value Query
Range
Subject
Range
gi|151940901 - gi|151940901|gb|EDN59283.1| conserved protein [Saccharomyces cerevisiae YJM789]
CSR1 - Phosphatidylinositol transfer protein with a potential role in regulating lipid and fatty acid metab...
CSR1_YEAST - Phosphatidylinositol transfer protein CSR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
gi|190405422 - gi|190405422|gb|EDV08689.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
0.0 [1..408] [1..408]
SPAC3H8.02 - sec14 cytosolic factor family
YAS2_SCHPO - CRAL-TRIO domain-containing protein C3H8.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
1.0E-83 [7..404] [11..412]
gi|22137166, gi|... - gi|22137166|gb|AAM91428.1| AT4g39170/T22F8_70 [Arabidopsis thaliana], gi|14335006|gb|AAK59767.1| AT4...
4.0E-68 [30..381] [37..403]
gi|14486705 - gi|14486705|gb|AAK63247.1|AF367433_1 phosphatidylinositol transfer-like protein III [Lotus japonicus...
4.0E-64 [30..380] [37..403]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-62 [30..381] [37..406]

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Predicted Domain #1
Region A:
Residues: [1-52]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFDRQLTED QEVVLKQIWT HLFHLWQVPV DGTHIFPNNS LHSSSTPAKK KK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
phospholipid transporter activity 4.82372291869245 bayes_pls_golite062009
lipid transporter activity 3.44932625048477 bayes_pls_golite062009
phosphatidylinositol transporter activity 3.08477039249457 bayes_pls_golite062009
binding 2.07778268514777 bayes_pls_golite062009
transporter activity 1.52591056865451 bayes_pls_golite062009
transcription regulator activity 1.36272499520472 bayes_pls_golite062009
vitamin binding 1.07146133708197 bayes_pls_golite062009
substrate-specific transporter activity 0.658164745879483 bayes_pls_golite062009
transmembrane transporter activity 0.387752763420225 bayes_pls_golite062009
protein binding 0.385179389448981 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [53-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSWFSKLQSS DHTQDSSEAA EAAHLYEKGK IHKALANLDP QTTKKQFWHD IKNETPDATI  60
   61 LKFIRARKWN ADKTIAMLGH DL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.9897
Match: 1aua__
Description: N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [135-408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YWRKDTINKI INGGERAVYE NNETGVIKNL ELQKATIQGY DNDMRPVILV RPRLHHSSDQ  60
   61 TEQELEKFSL LVIEQSKLFF KENYPASTTI LFDLNGFSMS NMDYAPVKFL ITCFEAHYPE 120
  121 SLGHLLIHKA PWIFNPIWNI IKNWLDPVVA SKIVFTKNID ELHKFIQPQY IPRYLGGEND 180
  181 NDLDHYTPPD GSLDVHLKDT ETRAMIEKER EELVEQFLTV TAQWIEHQPL NDPAYIQLQE 240
  241 KRVQLSTALC ENYSKLDPYI RSRSVYDYNG SLKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 127.9897
Match: 1aua__
Description: N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle