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View Structure Prediction Details

Protein: RSC2
Organism: Saccharomyces cerevisiae
Length: 889 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSC2.

Description E-value Query
Range
Subject
Range
RSC2 - Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-s...
RSC2_YEAST - Chromatin structure-remodeling complex subunit RSC2 OS=Saccharomyces cerevisiae (strain ATCC 204508 ...
gi|151940881 - gi|151940881|gb|EDN59263.1| RSC complex member [Saccharomyces cerevisiae YJM789]
0.0 [1..889] [1..889]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-91 [5..591] [504..1153]
gi|12083875, gi|... - gi|12083875|gb|AAG48933.1|AF177387_1 polybromo-1 [Homo sapiens], gi|119585646|gb|EAW65242.1| polybro...
4.0E-89 [5..591] [506..1154]
rsc1 - RSC complex subunit Rsc1
RSC1_SCHPO - Chromatin structure-remodeling complex subunit rsc1 OS=Schizosaccharomyces pombe (strain 972 / ATCC ...
2.0E-75 [10..612] [7..553]
gi|12802525 - gi|12802525|gb|AAK07919.1|AF318183_1 ring 3 [Mus musculus]
3.0E-73 [3..389] [60..459]

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Predicted Domain #1
Region A:
Residues: [1-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMPDDNSNSS TQNSSALYKD LRKEYESLFT LKEDSGLEIS PIFNVLPPKK DYPDYYAVIK  60
   61 NPVSFNTLKK RIPHYTDAQQ FMNDVVQIPW NAKTYNTRDS GIYKYALVLE KYLKDTIYPN 120
  121 LKEKYPQLVY PDLGPLPDEP GYEEFQQKLR EKAEEVARAN AARAESSSSM NSTEAARRLR 180
  181 KTRTSVKRE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.67837
Match: 1e6iA_
Description: GCN5
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [190-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEPGTDTNND EDYEATDMDI DNPKDADFPD LIRKPLININ PYTRKPLRDN RSTTPSHSGT  60
   61 PQPLGPRHRQ VSRTQVKRGR PPIIDL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [276-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYIQRMKNVM KVLKKEVLDS GIGLTDLFER LPDRHRDANY YIMIANPISL QDINKKVKTR  60
   61 RYKTFQEFQN DFNLMLTNFR ISHRGDPESI KISNILEKTF TSLARFELSK PDRSFIPE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 23.920819
Match: PF00439
Description: Bromodomain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [394-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GELRYPLDEV IVNNISYHVG DWALLRNQND PQKPIVGQIF RLWKTPDGKQ WLNACWYYRP  60
   61 EQTVHRVDRL FYKNEVMKTG QYRDHLVSNL VGKCYVIHFT RYQRGNPDMK LEGPLFVCEF 120
  121 RYNESDKIFN KIRTWKACLP EEIRDLDEAT IPVNGRKFFK YPSPIRHLLP A

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 40.721246
Match: PF01426
Description: BAH domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [565-682]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NATPHDRVPE PTMGSPDAPP LVGAVYMRPK MQRDDLGEYA TSDDCPRYII RPNDSPEEGQ  60
   61 VDIETGTITT NTPTANALPK TGYSSSKLSS LRYNRSSMSL ENQNAIGQQQ IPLSRVGS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [683-889]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGAGGPLTVQ GLKQHQLQRL QQQQHQYQQQ KRSQASRYNI PTIIDDLTSQ ASRGNLGNIM  60
   61 IDAASSFVLP ISITKNVDVL QRTDLHSQTK RSGREEMFPW KKTKGEILWF RGPSVIVNER 120
  121 IINSGDPHLS LPLNRWFTTN KKRKLEYEEV EETMEDVTGK DKDDDGLEPD VENEKESLPG 180
  181 PFVLGLRPSA KFTAHRLSML RPPSSSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle