| Protein: | EST2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 884 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EST2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..884] | [1..884] |
|
|
0.0 | [196..872] | [342..1103] |
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|
0.0 | [196..872] | [342..1103] |
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|
0.0 | [196..872] | [347..1093] |
|
|
0.0 | [158..872] | [310..1099] |
|
|
0.0 | [147..872] | [338..1162] |
|
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0.0 | [34..823] | [29..821] |
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|
0.0 | [57..819] | [80..908] |
|
Region A: Residues: [1-301] |
1 11 21 31 41 51
| | | | | |
1 MKILFEFIQD KLDIDLQTNS TYKENLKCGH FNGLDEILTT CFALPNSRKI ALPCLPGDLS 60
61 HKAVIDHCII YLLTGELYNN VLTFGYKIAR NEDVNNSLFC HSANVNVTLL KGAAWKMFHS 120
121 LVGTYAFVDL LINYTVIQFN GQFFTQIVGN RCNEPHLPPK WVQRSSSSSA TAAQIKQLTE 180
181 PVTNKQFLHK LNINSSSFFP YSKILPSSSS IKKLTDLREA IFPTNLVKIP QRLKVRINLT 240
241 LQKLLKRHKR LNYVSILNSI CPPLEGTVLD LSHLSRQSPK ERVLKFIIVI LQKLLPQEMF 300
301 G
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [302-584] |
1 11 21 31 41 51
| | | | | |
1 SKKNKGKIIK NLNLLLSLPL NGYLPFDSLL KKLRLKDFRW LFISDIWFTK HNFENLNQLA 60
61 ICFISWLFRQ LIPKIIQTFF YCTEISSTVT IVYFRHDTWN KLITPFIVEY FKTYLVENNV 120
121 CRNHNSYTLS NFNHSKMRII PKKSNNEFRI IAIPCRGADE EEFTIYKENH KNAIQPTQKI 180
181 LEYLRNKRPT SFTKIYSPTQ IADRIKEFKQ RLLKKFNNVL PELYFMKFDV KSCYDSIPRM 240
241 ECMRILKDAL KNENGFFVRS QYFFNTNTGV LKLFNVVNAS RVP
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [585-773] |
1 11 21 31 41 51
| | | | | |
1 KPYELYIDNV RTVHLSNQDV INVVEMEIFK TALWVEDKCY IREDGLFQGS SLSAPIVDLV 60
61 YDDLLEFYSE FKASPSQDTL ILKLADDFLI ISTDQQQVIN IKKLAMGGFQ KYNAKANRDK 120
121 ILAVSSQSDD DTVIQFCAMH IFVKELEVWK HSSTMNNFHI RSKSSKGIFR SLIALFNTRI 180
181 SYKTIDTNL
|
| Detection Method: | |
| Confidence: | 3.69897 |
| Match: | 1d0eA_ |
| Description: | MMLV reverse transcriptase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [774-884] |
1 11 21 31 41 51
| | | | | |
1 NSTNTVLMQI DHVVKNISEC YKSAFKDLSI NVTQNMQFHS FLQRIIEMTV SGCPITKCDP 60
61 LIEYEVRFTI LNGFLESLSS NTSKFKDNII LLRKEIQHLQ AYIYIYIHIV N
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.875 | 0.016 | telomerase holoenzyme complex | a.1.1 | Globin-like |
| View | Download | 0.918 | 0.016 | telomerase holoenzyme complex | a.24.4 | Hemerythrin |
| View | Download | 0.955 | 0.016 | telomerase holoenzyme complex | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.786 | 0.016 | telomerase holoenzyme complex | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.758 | 0.016 | telomerase holoenzyme complex | a.74.1 | Cyclin-like |
| View | Download | 0.737 | 0.016 | telomerase holoenzyme complex | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.653 | 0.016 | telomerase holoenzyme complex | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.647 | 0.016 | telomerase holoenzyme complex | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.647 | 0.016 | telomerase holoenzyme complex | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.614 | 0.016 | telomerase holoenzyme complex | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.609 | 0.016 | telomerase holoenzyme complex | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.602 | 0.016 | telomerase holoenzyme complex | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.594 | 0.016 | telomerase holoenzyme complex | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.580 | 0.016 | telomerase holoenzyme complex | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.572 | 0.016 | telomerase holoenzyme complex | a.29.2 | Bromodomain |
| View | Download | 0.564 | 0.016 | telomerase holoenzyme complex | a.39.1 | EF-hand |
| View | Download | 0.550 | 0.016 | telomerase holoenzyme complex | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.548 | 0.016 | telomerase holoenzyme complex | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.545 | 0.016 | telomerase holoenzyme complex | a.112.1 | Description not found. |
| View | Download | 0.545 | 0.016 | telomerase holoenzyme complex | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.538 | 0.016 | telomerase holoenzyme complex | a.7.1 | Spectrin repeat |
| View | Download | 0.533 | 0.016 | telomerase holoenzyme complex | a.158.1 | F-box domain |
| View | Download | 0.532 | 0.016 | telomerase holoenzyme complex | a.47.2 | t-snare proteins |
| View | Download | 0.515 | 0.016 | telomerase holoenzyme complex | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.512 | 0.016 | telomerase holoenzyme complex | a.24.3 | Cytochromes |
| View | Download | 0.480 | 0.016 | telomerase holoenzyme complex | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.477 | 0.016 | telomerase holoenzyme complex | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.476 | 0.016 | telomerase holoenzyme complex | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.471 | 0.016 | telomerase holoenzyme complex | a.47.2 | t-snare proteins |
| View | Download | 0.454 | 0.016 | telomerase holoenzyme complex | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.452 | 0.016 | telomerase holoenzyme complex | a.29.2 | Bromodomain |
| View | Download | 0.450 | 0.016 | telomerase holoenzyme complex | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.450 | 0.016 | telomerase holoenzyme complex | d.82.2 | Frataxin-like |
| View | Download | 0.445 | 0.016 | telomerase holoenzyme complex | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.442 | 0.016 | telomerase holoenzyme complex | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.441 | 0.016 | telomerase holoenzyme complex | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.430 | 0.016 | telomerase holoenzyme complex | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.428 | 0.016 | telomerase holoenzyme complex | a.26.1 | 4-helical cytokines |
| View | Download | 0.425 | 0.016 | telomerase holoenzyme complex | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.416 | 0.016 | telomerase holoenzyme complex | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.415 | 0.016 | telomerase holoenzyme complex | a.141.1 | Frizzled cystein-rich domain |
| View | Download | 0.415 | 0.016 | telomerase holoenzyme complex | a.4.12 | TrpR-like |
| View | Download | 0.411 | 0.016 | telomerase holoenzyme complex | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.401 | 0.016 | telomerase holoenzyme complex | a.7.1 | Spectrin repeat |
| View | Download | 0.387 | 0.016 | telomerase holoenzyme complex | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.384 | 0.016 | telomerase holoenzyme complex | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.383 | 0.016 | telomerase holoenzyme complex | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.381 | 0.016 | telomerase holoenzyme complex | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.381 | 0.016 | telomerase holoenzyme complex | a.24.3 | Cytochromes |
| View | Download | 0.375 | 0.016 | telomerase holoenzyme complex | a.59.1 | PAH2 domain |
| View | Download | 0.365 | 0.016 | telomerase holoenzyme complex | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.365 | 0.016 | telomerase holoenzyme complex | a.1.1 | Globin-like |
| View | Download | 0.364 | 0.016 | telomerase holoenzyme complex | g.36.1 | Ferredoxin thioredoxin reductase (FTR), catalytic beta chain |
| View | Download | 0.363 | 0.016 | telomerase holoenzyme complex | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.361 | 0.016 | telomerase holoenzyme complex | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.360 | 0.016 | telomerase holoenzyme complex | a.29.2 | Bromodomain |
| View | Download | 0.360 | 0.016 | telomerase holoenzyme complex | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.358 | 0.016 | telomerase holoenzyme complex | a.7.8 | GAT domain |
| View | Download | 0.354 | 0.016 | telomerase holoenzyme complex | d.80.1 | Tautomerase/MIF |
| View | Download | 0.350 | 0.016 | telomerase holoenzyme complex | a.46.1 | Methionine synthase domain |
| View | Download | 0.348 | 0.016 | telomerase holoenzyme complex | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.341 | 0.016 | telomerase holoenzyme complex | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.331 | 0.016 | telomerase holoenzyme complex | d.198.1 | Type III secretory system chaperone |
| View | Download | 0.331 | 0.016 | telomerase holoenzyme complex | a.25.1 | Ferritin-like |
| View | Download | 0.330 | 0.016 | telomerase holoenzyme complex | a.74.1 | Cyclin-like |
| View | Download | 0.326 | 0.016 | telomerase holoenzyme complex | a.74.1 | Cyclin-like |
| View | Download | 0.326 | 0.016 | telomerase holoenzyme complex | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.326 | 0.016 | telomerase holoenzyme complex | d.198.2 | Arp2/3 complex subunits |
| View | Download | 0.322 | 0.016 | telomerase holoenzyme complex | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.317 | 0.016 | telomerase holoenzyme complex | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.317 | 0.016 | telomerase holoenzyme complex | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.315 | 0.016 | telomerase holoenzyme complex | c.44.2 | Enzyme IIB-cellobiose |
| View | Download | 0.314 | 0.016 | telomerase holoenzyme complex | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.311 | 0.016 | telomerase holoenzyme complex | g.53.1 | TAZ domain |
| View | Download | 0.302 | 0.016 | telomerase holoenzyme complex | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.301 | 0.016 | telomerase holoenzyme complex | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.296 | 0.016 | telomerase holoenzyme complex | a.130.1 | Chorismate mutase II |
| View | Download | 0.292 | 0.016 | telomerase holoenzyme complex | f.1.5 | Exotoxin A, middle domain |
| View | Download | 0.285 | 0.016 | telomerase holoenzyme complex | a.72.1 | Functional domain of the splicing factor Prp18 |
| View | Download | 0.282 | 0.016 | telomerase holoenzyme complex | a.118.16 | Testis/brain RNA-binding protein (TB-RBP) |
| View | Download | 0.282 | 0.016 | telomerase holoenzyme complex | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.278 | 0.016 | telomerase holoenzyme complex | a.24.1 | Apolipoprotein |
| View | Download | 0.278 | 0.016 | telomerase holoenzyme complex | a.24.11 | Bacterial GAP domain |
| View | Download | 0.274 | 0.016 | telomerase holoenzyme complex | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.272 | 0.016 | telomerase holoenzyme complex | a.19.1 | Fertilization protein |
| View | Download | 0.271 | 0.016 | telomerase holoenzyme complex | a.1.1 | Globin-like |
| View | Download | 0.270 | 0.016 | telomerase holoenzyme complex | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.263 | 0.016 | telomerase holoenzyme complex | d.129.2 | Phosphoglucomutase, C-terminal domain |
| View | Download | 0.263 | 0.016 | telomerase holoenzyme complex | a.24.3 | Cytochromes |
| View | Download | 0.262 | 0.016 | telomerase holoenzyme complex | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.259 | 0.016 | telomerase holoenzyme complex | d.129.4 | Cell-division protein ZipA, C-terminal domain |
| View | Download | 0.259 | 0.016 | telomerase holoenzyme complex | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.254 | 0.016 | telomerase holoenzyme complex | a.3.1 | Cytochrome c |
| View | Download | 0.251 | 0.016 | telomerase holoenzyme complex | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.248 | 0.016 | telomerase holoenzyme complex | a.1.2 | alpha-helical ferredoxin |
| View | Download | 0.245 | 0.016 | telomerase holoenzyme complex | a.41.1 | Domain of poly(ADP-ribose) polymerase |
| View | Download | 0.244 | 0.016 | telomerase holoenzyme complex | a.118.8 | TPR-like |
| View | Download | 0.244 | 0.016 | telomerase holoenzyme complex | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.243 | 0.016 | telomerase holoenzyme complex | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.239 | 0.016 | telomerase holoenzyme complex | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.236 | 0.016 | telomerase holoenzyme complex | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.231 | 0.016 | telomerase holoenzyme complex | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.229 | 0.016 | telomerase holoenzyme complex | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.228 | 0.016 | telomerase holoenzyme complex | d.32.1 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| View | Download | 0.227 | 0.016 | telomerase holoenzyme complex | d.192.1 | YlxR-like |
| View | Download | 0.223 | 0.016 | telomerase holoenzyme complex | d.58.26 | GHMP Kinase, C-terminal domain |
| View | Download | 0.223 | 0.016 | telomerase holoenzyme complex | d.233.1 | Inhibitor of vertebrate lysozyme, Ivy |
| View | Download | 0.220 | 0.016 | telomerase holoenzyme complex | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.219 | 0.016 | telomerase holoenzyme complex | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.218 | 0.016 | telomerase holoenzyme complex | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.215 | 0.016 | telomerase holoenzyme complex | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.213 | 0.016 | telomerase holoenzyme complex | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.213 | 0.016 | telomerase holoenzyme complex | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.213 | 0.016 | telomerase holoenzyme complex | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.209 | 0.016 | telomerase holoenzyme complex | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.203 | 0.016 | telomerase holoenzyme complex | b.55.1 | PH domain-like |
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Region A: Residues: [583-747] |
1 11 21 31 41 51
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1 VPKPYELYID NVRTVHLSNQ DVINVVEMEI FKTALWVEDK CYIREDGLFQ GSSLSAPIVD 60
61 LVYDDLLEFY SEFKASPSQD TLILKLADDF LIISTDQQQV INIKKLAMGG FQKYNAKANR 120
121 DKILAVSSQS DDDTVIQFCA MHIFVKELEV WKHSSTMNNF HIRSK
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| Detection Method: | |
| Confidence: | 5.0 |
| Match: | 1nndA |
| Description: | Arginine 116 is Essential for Nucleic Acid Recognition by the Fingers Domain of Moloney Murine Leukemia Virus Reverse Transcriptase |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [748-884] |
1 11 21 31 41 51
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1 SSKGIFRSLI ALFNTRISYK TIDTNLNSTN TVLMQIDHVV KNISECYKSA FKDLSINVTQ 60
61 NMQFHSFLQR IIEMTVSGCP ITKCDPLIEY EVRFTILNGF LESLSSNTSK FKDNIILLRK 120
121 EIQHLQAYIY IYIHIVN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.955 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.918 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.900 | N/A | N/A | a.29.4 | RecG, N-terminal domain |
| View | Download | 0.875 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.868 | N/A | N/A | a.1.1 | Globin-like |
