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View Structure Prediction Details

Protein: RCK2
Organism: Saccharomyces cerevisiae
Length: 610 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RCK2.

Description E-value Query
Range
Subject
Range
RCK2 - Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of...
RCK2_YEAST - Serine/threonine-protein kinase RCK2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RCK...
gi|151941084 - gi|151941084|gb|EDN59464.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..610] [1..610]
gi|7339534 - gi|7339534|emb|CAB82852.1| protein kinase MK6 [Mesembryanthemum crystallinum]
0.0 [46..582] [17..547]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [121..582] [6..462]
gi|17381026, gi|... - gi|22331282|ref|NP_188973.2| protein kinase, putative [Arabidopsis thaliana], gi|20465361|gb|AAM2008...
0.0 [54..581] [16..537]
LATS2 - LATS, large tumor suppressor, homolog 2 (Drosophila)
0.0 [5..582] [520..1074]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKIKALFSK KKPDQADLSQ ESKKPFKGKT RSSGTNNKDV SQITSSPKKS FQDKNIVQYP  60
   61 SVVADDHHMK SLTDELVTTI DSDSSPSDNI TTENVETVTS VPAIDVHESS EGQLSSDPLI 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [121-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDESLSEQSE IISDIQDDST DDDNMEDEIP EKSFLEQKEL IGYKLINKIG EGAFSKVFRA  60
   61 IPAKNSSNEF LTKNYKAVAI KVIKKADLSS INGDHRKKDK GKDSTKTSSR DQVLKEVALH 120
  121 KTVSAGCSQI VAFIDFQETD SYYYIIQELL TG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 519.855515
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [273-532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEIFGEIVRL TYFSEDLSRH VIKQLALAVK HMHSLGVVHR DIKPENLLFE PIEFTRSIKP  60
   61 KLRKSDDPQT KADEGIFTPG VGGGGIGIVK LADFGLSKQI FSKNTKTPCG TVGYTAPEVV 120
  121 KDEHYSMKVD MWGIGCVLYT MLCGFPPFYD EKIDTLTEKI SRGEYTFLKP WWDEISAGAK 180
  181 NAVAKLLELE PSKRYDIDQF LDDPWLNTFD CLPKEGESSQ KKAGTSERRH PHKKQFQLFQ 240
  241 RDSSLLFSPA AVAMRDAFDI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 519.855515
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [533-610]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNAVKRTEED RMGTRGGLGS LAEDEELEDS YSGAQGDEQL EQNMFQLTLD TSTILQRRKK  60
   61 VQENDVGPTI PISATIRE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle