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View Structure Prediction Details

Protein: MSC3
Organism: Saccharomyces cerevisiae
Length: 728 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSC3.

Description E-value Query
Range
Subject
Range
MSC3 - Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cell pe...
MSC3_YEAST - Meiotic sister-chromatid recombination protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S...
0.0 [1..728] [1..728]
gi|2213830 - gi|2213830|gb|AAB61579.1| nucleus and microtubule-associated protein [Cricetulus longicaudatus]
0.005 [508..700] [263..440]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFGFTKRDR RVPDLSRYDY YYQNHEDYNK SPQLSAAAAS AASAASPDRT NYSRSHSLVS  60
   61 HAPSIPRQRS SVKSPGRRLS TSSAAPPTSR AAAKQYSQKT YSLRSQRSGE YHLHPPGYTT 120
  121 NGSRMNSMTS GANVRRNYGK NKSTAGNNND SRANSITVKT TQVTDP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.14
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [167-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGRTQSITKK TIRKINGYEY VETTTTTKNL VPLGDSQRHF DEFSENYMLQ DDDILEEQAS  60
   61 DNIHDIIEEN ETDNEKPYSP VSESHLQDDS ELNVEKPDFP LGSYFHHKYS TDVMPLEEES 120
  121 SLSNFSDALD YIPPTHQTSS KYIHNKRKQA STTRRKKRPP AVKNAEAEAK KPLTEAEMYL 180
  181 KALEVAKRNV YHTDAASDNA SAPLGSNKSR KSRMGQKMTL RSSSDSPTAT ANLVKSNVEV 240
  241 QPKRFTSSFF SRNTKSAPHE VHNHSVSTHF KSNKAVDPVP EPKSANTGLT DKEMYDQALK 300
  301 IAQARYYNSH GIQPEAVDNS TTAAKPRQVG VSHLGSTGSI PPNEQHYLGD SEIPVQSEV

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.93
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [526-665]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HEYEPIPLQK TKTTGSSKNK FKTMFDKVLQ FSQENYGYQH KKEQGEQTPV TRNAEESFPA  60
   61 ASISEGVTTA KPSSNEGVMT NPVVTDSPSP LQQQIDSTTA SSNGQSQGNV PTSAVASTTR 120
  121 TRSPELQDNL KSSSSLLQDQ 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.93
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [666-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPQRQEDATD PTTSSTNELS AAEPTMVTST HATKTIQAQT QDPPTKHKKS SFFTKLFKKK  60
   61 SSR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.396 0.898 reciprocal meiotic recombination d.50.1 dsRNA-binding domain-like
View Download 0.412 0.898 reciprocal meiotic recombination d.10.1 DNA-binding domain
View Download 0.499 0.898 reciprocal meiotic recombination d.37.1 CBS-domain
View Download 0.431 0.898 reciprocal meiotic recombination d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.420 0.898 reciprocal meiotic recombination b.49.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.388 0.898 reciprocal meiotic recombination d.58.17 Metal-binding domain
View Download 0.386 0.898 reciprocal meiotic recombination d.59.1 Ribosomal protein L30p/L7e
View Download 0.369 0.898 reciprocal meiotic recombination d.58.17 Metal-binding domain
View Download 0.368 0.898 reciprocal meiotic recombination d.9.2 Description not found.
View Download 0.365 0.898 reciprocal meiotic recombination a.6.1 Putative DNA-binding domain
View Download 0.345 0.898 reciprocal meiotic recombination d.9.2 Description not found.
View Download 0.336 0.898 reciprocal meiotic recombination d.58.17 Metal-binding domain
View Download 0.323 0.898 reciprocal meiotic recombination d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.321 0.898 reciprocal meiotic recombination d.58.10 Acylphosphatase-like
View Download 0.321 0.898 reciprocal meiotic recombination d.58.7 RNA-binding domain, RBD
View Download 0.319 0.898 reciprocal meiotic recombination d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.310 0.898 reciprocal meiotic recombination d.58.17 Metal-binding domain
View Download 0.310 0.898 reciprocal meiotic recombination d.58.17 Metal-binding domain
View Download 0.300 0.898 reciprocal meiotic recombination b.55.1 PH domain-like
View Download 0.293 0.898 reciprocal meiotic recombination d.58.17 Metal-binding domain
View Download 0.290 0.898 reciprocal meiotic recombination d.57.1 DNA damage-inducible protein DinI
View Download 0.281 0.898 reciprocal meiotic recombination a.4.5 "Winged helix" DNA-binding domain
View Download 0.276 0.898 reciprocal meiotic recombination d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.270 0.898 reciprocal meiotic recombination d.212.1 TolA/TonB C-terminal domain
View Download 0.254 0.898 reciprocal meiotic recombination d.9.2 Description not found.
View Download 0.254 0.898 reciprocal meiotic recombination d.141.1 Ribosomal protein L6
View Download 0.251 0.898 reciprocal meiotic recombination a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.249 0.898 reciprocal meiotic recombination a.4.5 "Winged helix" DNA-binding domain
View Download 0.249 0.898 reciprocal meiotic recombination a.28.1 ACP-like
View Download 0.249 0.898 reciprocal meiotic recombination d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.241 0.898 reciprocal meiotic recombination b.84.2 Rudiment single hybrid motif
View Download 0.226 0.898 reciprocal meiotic recombination a.35.1 lambda repressor-like DNA-binding domains
View Download 0.222 0.898 reciprocal meiotic recombination d.9.1 Interleukin 8-like chemokines
View Download 0.222 0.898 reciprocal meiotic recombination b.84.1 Single hybrid motif
View Download 0.212 0.898 reciprocal meiotic recombination d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.211 0.898 reciprocal meiotic recombination a.35.1 lambda repressor-like DNA-binding domains
View Download 0.210 0.898 reciprocal meiotic recombination a.60.2 RuvA domain 2-like
View Download 0.210 0.898 reciprocal meiotic recombination d.58.5 GlnB-like
View Download 0.205 0.898 reciprocal meiotic recombination d.58.3 Protease propeptides/inhibitors
View Download 0.202 0.898 reciprocal meiotic recombination a.6.1 Putative DNA-binding domain

Predicted Domain #5
Region A:
Residues: [689-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTMVTSTHAT KTIQAQTQDP PTKHKKSSFF TKLFKKKSSR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle