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View Structure Prediction Details

Protein: PWP1
Organism: Saccharomyces cerevisiae
Length: 576 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PWP1.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [2..574] [909..1476]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
0.0 [46..540] [825..1314]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISATNWVPR GFSSEFPEKY VLDDEEVERI NQLAQLNLDD AKATLEEAEG ESGVEDDAAT  60
   61 GSSNKLKDQL DIDDDLKEYN LEEYDDEEIA DNEGGKDVSM FPGLSNDSDV KFHEG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [116-454]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKGEDPYISL PNQEDSQEEK QELQVYPSDN LVLAARTEDD VSYLDIYVYD DGAGFHSSDI  60
   61 PVEEGDEADP DVARGLVRDP ALYVHHDLML PAFPLCVEWL DYKVGSNSEE AANYAAIGTF 120
  121 DPQIEIWNLD CVDKAFPDMI LGEPLDNSMV SLKSKKKKKK SKTGHITTHH TDAVLSMAHN 180
  181 KYFRSVLAST SADHTVKLWD LNSGNAARSL ASIHSNKNVS SSEWHMLNGS ILLTGGYDSR 240
  241 VALTDVRISD ESQMSKYWSA MAGEEIETVT FASENIILCG TDSGNVYSFD IRNNENRKPV 300
  301 WTLKAHDAGI STLCSNKFIP GMMSTGAMGE KTVKLWKFP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.30103
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [455-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDDATNTKGP SMVLSRDFDV GNVLTSSFAP DIEVAGTMVI GGVNKVLKLW DVFTNRSVRK  60
   61 SFKSELENVQ ARAKEEAQKI GKSSRIARKY TSNDNPDTVI TIDDQGEDEE EREGGDEHDD 120
  121 MA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.1
Match: 1jjuB
Description: Quinohemoprotein amine dehydrogenase B chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.42725361829881 bayes_pls_golite062009
catalytic activity 0.233388920718075 bayes_pls_golite062009
protein binding 0.220695015309846 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [407-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNNENRKPVW TLKAHDAGIS TLCSNKFIPG MMSTGAMGEK TVKLWKFPLD DATNTKGPSM  60
   61 VLSRDFDVGN VLTSSFAPDI EVAGTMVIGG VNKVLKLWDV FTNRSVRKSF KSELENVQAR 120
  121 AKEEAQKIGK SSRIARKYTS NDNPDTVITI DDQGEDEEER EGGDEHDDMA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.69897
Match: 2ovpB
Description: No description for 2ovpB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle