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View Structure Prediction Details

Protein: YLL054C
Organism: Saccharomyces cerevisiae
Length: 769 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLL054C.

Description E-value Query
Range
Subject
Range
YLL054C - Putative protein of unknown function with similarity to Pip2p, an oleate-specific transcriptional ac...
0.0 [1..769] [1..769]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [4..673] [28..641]
THI1_SCHPO - Thiamine repressible genes regulatory protein thi1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2...
thi1 - transcription factor Thi1
0.0 [4..673] [28..641]
SPAC3C7.04 - transcription factor
YF54_SCHPO - Uncharacterized transcriptional regulatory protein C3C7.04 OS=Schizosaccharomyces pombe (strain 972 ...
7.0E-80 [7..621] [32..603]

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Predicted Domain #1
Region A:
Residues: [1-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIASQKKVK PSFVCLRCKQ RKIKCDKLWP TCSKCKASSS ICSYEVEPGR INKSPTIENA  60
   61 PHRDIRNITP ASMSASGSFT SILNPSTKDW EMKNFAMNLS NAHDKLVVMN NTTIVDSPFA 120
  121 FHSILQHDLY AKALTTCIHE RILIDVERHR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1pyiA_
Description: PPR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.16002381293778 bayes_pls_golite062009
DNA binding 3.92936270801133 bayes_pls_golite062009
nucleic acid binding 3.76909067702445 bayes_pls_golite062009
binding 2.91929847152301 bayes_pls_golite062009
transcription factor activity 2.76608547022152 bayes_pls_golite062009
sequence-specific DNA binding 1.80020012839068 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.69026374220371 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.54700248976411 bayes_pls_golite062009
transcription activator activity 0.778623988601299 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [151-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENVSANNKKR ELNLTIGDIG PLFFIDKAAL KFIENTSKTS KLYPPIDFLY NTYDYEQAHP  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [211-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EENNDKISIN ILLEELSKYF 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [244-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKTIYPVYPL L

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [388-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEEPFQYTRY VSESDDYPRL FNLRRKLW

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.29
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [231-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNKNEVDGLI VDF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [255-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EISLFEDNIR ELLQLNEFNG YNIVFAGKDS RRKLETITLL TIILAFSYRR LSLSTSHSFK  60
   61 ESFGVKSNNL TLLAHKLLAL MNVFQYVNEH TLCCLLYFFI LRYLNPDQAD MYPTHSDILN 120
  121 LKFLENVAIK LGL

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [416-705]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGVQFLKFGI LIPEGDSDIL SLEYLRSFMK TDESLPELFE RNYASTNNLD LSLMATAENI  60
   61 YHLHLSLQVL LTSCFPINGP SYLKEVLDNI DKTKDFLNQK FPLILSSLGE PRMKSLHINV 120
  121 PSSLANEESF DFSTFEENET FIANVISYTC TMNIYDSLSL HFENQCFKNA LEYKTYYHRF 180
  181 TFTAIQDYLT LLKLISEYFN GSLLHLREPF GFATQKVVRF SIHRLLIFQA TLLVRLFYKK 240
  241 DTCDRSSAAM GMLNDRNGRL SRVIEKMIKL MSYHMKLLVE IVISKLEKSY 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.29
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [706-769]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGSFISVSIF RYIIYLVDTD ALSAFISDYW KSDAVMDERY SRIHRIVGLK WGMGRDKSFS  60
   61 FTQN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.745 0.802 transcription activator activity a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #6
Region A:
Residues: [673-769]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRLSRVIEKM IKLMSYHMKL LVEIVISKLE KSYLGSFISV SIFRYIIYLV DTDALSAFIS  60
   61 DYWKSDAVMD ERYSRIHRIV GLKWGMGRDK SFSFTQN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle