| Protein: | SPA2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1466 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPA2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1466] | [1..1466] |
|
|
1.0E-57 | [103..1364] | [1167..2453] |
|
|
1.0E-48 | [53..1186] | [216..1330] |
|
|
1.0E-48 | [53..1186] | [160..1274] |
|
|
4.0E-47 | [453..1292] | [41..872] |
|
|
9.0E-46 | [701..1306] | [763..1366] |
|
Region A: Residues: [1-284] |
1 11 21 31 41 51
| | | | | |
1 MGTSSEVSLA HHRDIFHYYV SLKTFFEVTG ENRDRSNSTR AQKARAKLLK LSSSQFYELS 60
61 TDVSDELQRR IGEDANQPDY LLPKANFHMK RNQARQKLAN LSQTRFNDLL DDILFEIKRR 120
121 GFDKDLDAPR PPLPQPMKQE VSKDSDDTAR TSTNSSSVTQ VAPNVSVQPS LVIPKMASID 180
181 WSSEEEEEEQ VKEKPNEPEG KQTSMDEKKE AKPALNPIVT DSDLPDSQVL ARDITSMART 240
241 PTTTHKNYWD VNDSPIIKVD KDIDNEKGPE QLKSPEVQRA ENNN
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [285-373] |
1 11 21 31 41 51
| | | | | |
1 PNSEMEDKVK ELTDLNSDLH LQIEDLNAKL ASLTSEKEKE KKEEKEEKEK EKNLKINYTI 60
61 DESFQKELLS LNSQIGELSI ENENLKQKI
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.570 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.684 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.516 | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.760 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.452 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.417 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.395 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.394 | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.359 | d.42.1 | POZ domain |
| View | Download | 0.358 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.348 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.338 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.331 | b.82.4 | Regulatory protein AraC |
| View | Download | 0.323 | a.77.1 | DEATH domain |
| View | Download | 0.306 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.306 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.304 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.293 | a.64.1 | Saposin |
| View | Download | 0.277 | a.7.1 | Spectrin repeat |
| View | Download | 0.276 | a.68.1 | Wiscott-Aldrich syndrome protein, WASP, C-terminal domain |
| View | Download | 0.236 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.234 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.231 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.228 | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.222 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.221 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.220 | a.1.1 | Globin-like |
| View | Download | 0.220 | a.144.2 | Ribosomal protein L20 |
| View | Download | 0.218 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.218 | d.45.1 | ClpS-like |
| View | Download | 0.214 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.214 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.213 | a.74.1 | Cyclin-like |
| View | Download | 0.209 | a.58.1 | Chemotaxis receptor methyltransferase CheR, N-terminal domain |
| View | Download | 0.204 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.201 | a.2.3 | Chaperone J-domain |
|
Region A: Residues: [374-959] |
1 11 21 31 41 51
| | | | | |
1 SEFELHQKKN DNHNDLKITD GFISKYSSAD GLIPAQYILN ANNLIIQFTT RLSAVPIGDS 60
61 TAISHQIGEE LFQILSQLSN LISQLLLSAD LLQYKDQVIL LKASLSHAIT SIRYFSVYGP 120
121 VLIPKITVQA AVSEVCFAMC NLIDSAKIKS DSNGESTTSN EGNRQVLEYS SPTATTPMTP 180
181 TFPSTSGINM KKGFINPRKP ASFLNDVEEE ESPVKPLKIT QKAINSPIIR PSSSNGVPTT 240
241 SRKPSGTGLF SLMIDSSIAK NSSHKEDNDK YVSPIKAVTS ASNSASSNIS EIPKLTLPPQ 300
301 AKIGTVIPPS ENQVPNIKIE NTEEDNKRSD ITNEISVKPT SSIADKLKQF EQSSEKKSSP 360
361 KENPIAKEEM DSKPKLSNKF ITSMNDVSTD DSSSDGNEND DADDDDDFTY MALKQTMKRE 420
421 GSKIEKNNDS KLPANIVELD LHESPESVKI ESPESIKEIT SSEMSSEMPS SSLPKRLVED 480
481 VEPSEMPEKG ASVESVRKKN FQEPLGNVES PDMTQKVKSL GMTGKAVGPE SDSRVESPGM 540
541 TGQIKSLNMA GKVVGPEADS RVESPGMKEQ IKSLGMTGKI TAQESI
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [960-1352] |
1 11 21 31 41 51
| | | | | |
1 KSPEAARKLA SSGEVDKIES PRMVRESESL EAVGNTIPSN MTVKMESPNL KGNTVSEPQE 60
61 IRRDIASSEP IENVDPPKVL KKIVFPKAVN RTGSPKSVEK TPSSATLKKS GLPEPNSQIV 120
121 SPELAKNSPL APIKKNVELR ETNKPHTETI TSVEPTNKDA NTSWRDADLN RTIKREEEDE 180
181 DFDRVNHNIQ ITGAYTKTGK IDYHKIPVDR KAKSEAEVHT SEEDIDESNN VNGKRADAQI 240
241 HITERKHAFV NPTENSQVKK TSHSPFLNSK PVQYENSESN GGINNHIKIK NTGETTAHDE 300
301 KHYSDDDDSS YQFVPMKHEE QEQEQNRSEE EESEDDDEEE EDSDFDVDTF DIENPDNTLS 360
361 ELLLYLEHQT MDVISTIQSL LTSIKKPQVT KGN
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1353-1466] |
1 11 21 31 41 51
| | | | | |
1 LRGESNAINQ VIGQMVDATS ISMEQSRNAN LKKHGDWVVQ SLRDCSRRMT ILCQLTGDGI 60
61 LAKEKSDQDY ADKNFKQRLA GIAFDVAKCT KELVKTVEEA SLKDEINYLN SKLK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.800 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.935 | a.24.3 | Cytochromes |
| View | Download | 0.861 | a.7.7 | BAG domain |
| View | Download | 0.955 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.663 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.585 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.584 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.570 | a.25.1 | Ferritin-like |
| View | Download | 0.563 | a.25.1 | Ferritin-like |
| View | Download | 0.563 | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.535 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.510 | a.25.1 | Ferritin-like |
| View | Download | 0.510 | a.165.1 | Myosin phosphatase inhibitor 17kDa protein, CPI-17 |
| View | Download | 0.510 | a.2.7 | tRNA-binding arm |
| View | Download | 0.505 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.499 | a.24.1 | Apolipoprotein |
| View | Download | 0.493 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.485 | a.25.1 | Ferritin-like |
| View | Download | 0.471 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.457 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.456 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.454 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.450 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.447 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.435 | d.232.1 | Mago nashi protein |
| View | Download | 0.425 | a.25.1 | Ferritin-like |
| View | Download | 0.415 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.410 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.405 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.400 | a.39.1 | EF-hand |
| View | Download | 0.392 | a.47.2 | t-snare proteins |
| View | Download | 0.384 | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.381 | f.25.1 | Cytochrome c oxidase subunit III-like |
| View | Download | 0.379 | a.47.2 | t-snare proteins |
| View | Download | 0.364 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.364 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.363 | a.25.1 | Ferritin-like |
| View | Download | 0.356 | a.72.1 | Functional domain of the splicing factor Prp18 |
| View | Download | 0.351 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.348 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.345 | a.69.1 | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.344 | a.7.7 | BAG domain |
| View | Download | 0.341 | a.1.1 | Globin-like |
| View | Download | 0.341 | a.24.3 | Cytochromes |
| View | Download | 0.340 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.339 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.335 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.335 | a.7.1 | Spectrin repeat |
| View | Download | 0.333 | f.21.1 | Transmembrane di-heme cytochromes |
| View | Download | 0.329 | a.47.2 | t-snare proteins |
| View | Download | 0.325 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.324 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.322 | a.25.1 | Ferritin-like |
| View | Download | 0.319 | a.30.1 | ROP protein |
| View | Download | 0.318 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.309 | d.58.16 | Poly(A) polymerase, C-terminal domain |
| View | Download | 0.307 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.304 | a.7.1 | Spectrin repeat |
| View | Download | 0.301 | a.118.9 | ENTH/VHS domain |
| View | Download | 0.301 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.296 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.293 | a.47.2 | t-snare proteins |
| View | Download | 0.292 | a.11.2 | Second domain of FERM |
| View | Download | 0.291 | a.25.1 | Ferritin-like |
| View | Download | 0.289 | a.60.10 | Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain |
| View | Download | 0.287 | a.47.2 | t-snare proteins |
| View | Download | 0.284 | a.7.1 | Spectrin repeat |
| View | Download | 0.281 | a.74.1 | Cyclin-like |
| View | Download | 0.278 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.276 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.274 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.272 | a.7.7 | BAG domain |
| View | Download | 0.272 | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.262 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.257 | a.118.8 | TPR-like |
| View | Download | 0.250 | a.24.3 | Cytochromes |
| View | Download | 0.250 | a.26.1 | 4-helical cytokines |
| View | Download | 0.238 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.237 | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.235 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.235 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.234 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.225 | a.79.1 | Antitermination factor NusB |
| View | Download | 0.225 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.224 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.222 | c.44.2 | Enzyme IIB-cellobiose |
| View | Download | 0.221 | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.215 | d.185.1 | LuxS/MPP-like metallohydrolase |
| View | Download | 0.215 | a.7.1 | Spectrin repeat |
| View | Download | 0.211 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.211 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.211 | a.26.1 | 4-helical cytokines |
| View | Download | 0.208 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.207 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.206 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.203 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.201 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
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Region A: Residues: [825-947] |
1 11 21 31 41 51
| | | | | |
1 SPESIKEITS SEMSSEMPSS SLPKRLVEDV EPSEMPEKGA SVESVRKKNF QEPLGNVESP 60
61 DMTQKVKSLG MTGKAVGPES DSRVESPGMT GQIKSLNMAG KVVGPEADSR VESPGMKEQI 120
121 KSL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [948-1100] |
1 11 21 31 41 51
| | | | | |
1 GMTGKITAQE SIKSPEAARK LASSGEVDKI ESPRMVRESE SLEAVGNTIP SNMTVKMESP 60
61 NLKGNTVSEP QEIRRDIASS EPIENVDPPK VLKKIVFPKA VNRTGSPKSV EKTPSSATLK 120
121 KSGLPEPNSQ IVSPELAKNS PLAPIKKNVE LRE
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1101-1353] |
1 11 21 31 41 51
| | | | | |
1 TNKPHTETIT SVEPTNKDAN TSWRDADLNR TIKREEEDED FDRVNHNIQI TGAYTKTGKI 60
61 DYHKIPVDRK AKSEAEVHTS EEDIDESNNV NGKRADAQIH ITERKHAFVN PTENSQVKKT 120
121 SHSPFLNSKP VQYENSESNG GINNHIKIKN TGETTAHDEK HYSDDDDSSY QFVPMKHEEQ 180
181 EQEQNRSEEE ESEDDDEEEE DSDFDVDTFD IENPDNTLSE LLLYLEHQTM DVISTIQSLL 240
241 TSIKKPQVTK GNL
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1354-1466] |
1 11 21 31 41 51
| | | | | |
1 RGESNAINQV IGQMVDATSI SMEQSRNANL KKHGDWVVQS LRDCSRRMTI LCQLTGDGIL 60
61 AKEKSDQDYA DKNFKQRLAG IAFDVAKCTK ELVKTVEEAS LKDEINYLNS KLK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.955 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.935 | a.24.3 | Cytochromes |
| View | Download | 0.880 | a.24.3 | Cytochromes |
| View | Download | 0.861 | a.7.7 | BAG domain |
| View | Download | 0.810 | a.47.2 | t-snare proteins |
