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View Structure Prediction Details

Protein: TGL4
Organism: Saccharomyces cerevisiae
Length: 910 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TGL4.

Description E-value Query
Range
Subject
Range
gi|207343323 - gi|207343323|gb|EDZ70811.1| YKR089Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190409901 - gi|190409901|gb|EDV13166.1| hypothetical protein SCRG_04104 [Saccharomyces cerevisiae RM11-1a]
TGL4 - Multifunctional triacylglycerol lipase, steryl ester hydrolase, and Ca2+-independent phospholipase A...
TGL4_YEAST - Lipase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TGL4 PE=1 SV=1
0.0 [1..910] [1..910]
SDP1_ARATH - Triacylglycerol lipase SDP1 OS=Arabidopsis thaliana GN=SDP1 PE=1 SV=1
0.0 [152..700] [105..638]
gi|20804680, gi|... - gi|50902030|ref|XP_463448.1| P0512C01.22 [Oryza sativa (japonica cultivar-group)], gi|20804680|dbj|B...
0.0 [152..680] [106..615]
YEX5_SCHPO - Uncharacterized protein C1A6.05c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC1A6.0...
SPAC1A6.05c - triacylglycerol lipase
0.0 [151..632] [9..478]
gi|7630152 - gi|7630152|emb|CAB88226.1| conserved hypothetical protein L5213T.05 [Leishmania major]
9.0E-76 [267..629] [523..884]
gi|9794868 - gi|9794868|gb|AAF98368.1|AF158027_1 patatin-like protein 1 [Nicotiana tabacum]
1.0E-75 [280..678] [24..412]
gi|4539677, gi|2... - gi|4539677|gb|AAD22170.1|AF061282_24 patatin-like protein [Sorghum bicolor], gi|242071683|ref|XP_002...
2.0E-74 [280..668] [26..405]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKISDLTS TQNKPLLVTQ QLIEKYYEQI LGTSQNIIPI LNPKNKFIRP SKDNSDVERV  60
   61 EEDAGKRLQT GKNKTTNKVN FNLDTGNEDK LDDDQETVTE NENNDIEMVE TD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [113-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGEDERQGSS LASKCKSFLY NVFVGNYERD ILIDKVCSQK QHAMSFEEWC SAGARLDDLT  60
   61 GKTEWKQKLE SPLYDYKLIK DLTSRMREER LNRNYAQLLY IIRTNWVRNL GNMGNVNLYR 120
  121 HSHVGTKYLI DEYMMESRLA LESLMES

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [260-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLDDSYLLGI LQQTRRNIGR TALVLSGGGT FGLFHIGVLG TLFELDLLPR VISGSSAGAI  60
   61 VASILSVHHK EEIPVLLNHI LDKEFNIFKD DKQKSESENL LIKISRFFKN GTWFDNKHLV 120
  121 NTMIEFLGDL TFREAYNRTG KILNITVSPA SLFEQPRLLN NLTAPNVLIW SAVCASCSLP 180
  181 GIFPSSPLYE KDPKTGERKP WTGSSSVKFV DGSVDNDLPI SRLSEMFNVD HIIACQVNIH 240
  241 VFPFLK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 56.455932
Match: PF01734
Description: Patatin-like phospholipase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
phospholipase A2 activity 2.22630563405125 bayes_pls_golite062009
phospholipase activity 2.02363770793596 bayes_pls_golite062009
lipase activity 1.83391969295473 bayes_pls_golite062009
catalytic activity 1.681309422157 bayes_pls_golite062009
[acyl-carrier-protein] S-malonyltransferase activity 1.27314027329282 bayes_pls_golite062009
S-malonyltransferase activity 1.27314027329282 bayes_pls_golite062009
malonyltransferase activity 1.27314027329282 bayes_pls_golite062009
hydrolase activity 0.755660272658182 bayes_pls_golite062009
fatty acid synthase activity 0.432469017757431 bayes_pls_golite062009
carboxylesterase activity 0.431665185524913 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.39017969987234 bayes_pls_golite062009
S-acyltransferase activity 0.28475890150768 bayes_pls_golite062009
binding 0.112552746544258 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [506-772]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSLSCVGGEI EDEFSARLKQ NLSSIYNFMA NEAIHILEIG SEMGIAKNAL TKLRSVLSQQ  60
   61 YSGDITILPD MCMLFRIKEL LSNPTKEFLL REITNGAKAT WPKVSIIQNH CGQEFALDKA 120
  121 ISYIKGRMIV TSSLKTPFQF ADSVIGLIKA PEQTSDESKN PENSTLLTRT PTKGDNHISN 180
  181 VLDDNLLESE STNSLLLLRE NASTYGRSPS GFRPRYSITS ASLNPRHQRR KSDTISTSRR 240
  241 PAKSFSFSVA SPTSRMLRQS SKINGHP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [773-910]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPILQKKTSM GRLMFPMDAK TYDPESHELI PHSASIETPA MVDKKLHFGR KSRYLRHMNK  60
   61 KWVSSSNILY TDSDKEDHPT LRLISNFDSD AMIHSDLAGN FRRHSIDGRP PSQATKSSPF 120
  121 RSRPSSSTQH KSTTSFTQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle