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View Structure Prediction Details

Protein: UIP5
Organism: Saccharomyces cerevisiae
Length: 443 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UIP5.

Description E-value Query
Range		 Subject
Range
UIP5 - Protein of unknown function that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific prote...
UIP5_YEAST - Protein UIP5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UIP5 PE=1 SV=1
 0.0 [1..443] [1..443]
LMAN1_RAT - Protein ERGIC-53 OS=Rattus norvegicus GN=Lman1 PE=1 SV=1
 1.0E-85 [18..360] [19..317]
ergic53-PA, ergi... - The gene ergic53 is referred to in FlyBase by the symbol Dmel\ergic53 (CG6822, FBgn0035909). It is a...
gi|220956014 - gi|220956014|gb|ACL90550.1| ergic53-PA [synthetic construct]
 2.0E-85 [40..360] [20..295]
LMAN1_MOUSE - Protein ERGIC-53 OS=Mus musculus GN=Lman1 PE=1 SV=1
 2.0E-85 [18..360] [19..317]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 4.0E-83 [37..360] [20..309]
LMAN1 - lectin, mannose-binding, 1
 5.0E-83 [37..360] [20..309]
LMAN1_CHLAE - Protein ERGIC-53 OS=Chlorocebus aethiops GN=LMAN1 PE=2 SV=1
 6.0E-83 [15..360] [16..309]
ile-1 - P58 protein like status:Confirmed UniProt:P90913 protein_id:CAB03169.1
 8.0E-81 [44..362] [17..290]

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Predicted Domain #1
Region A:
Residues: [1-367] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRDVRAEKL AISLLILSLF LIFQLVAEIY LNNGDQYHTE TSPFTRGRSH VTRVPNHDAS  60
   61 LSIPFLDKIN QFWHVGGATQ IRNIQSIKLT QDRDQDKHGL VLSNGIGDNT INDFEIVFTF 120
  121 RISHDPTTQL TGDGMCFAIT PENGFLTQNL QSSYAKKQYM MNSQGVIADN TDLMGFPKNL 180
  181 PGLFIVLDTY RNQGHDHKEV PFMDVFINVA PESDWYDINS DGELSTSLRL NSRGHIKLKK 240
  241 NALWNRVTKL RIIYLESISF LKIDVQYAKE GNYWIELFQT TENLYLPKNM HTGQRYIGCS 300
  301 ALNGQLTETV ELLDVSTSEF HWNDMDASIE DTYDYAKEAE LFLEQEFGEV LDREPDEFTK 360
  361 WKMIKAQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.69897
Match: 1gv9A_
Description: Carbohydrate-recognition domain of P58/ERGIC-53
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.80812953968012 bayes_pls_golite062009
transcription regulator activity 1.04975759390661 bayes_pls_golite062009
nucleic acid binding 1.04598570598417 bayes_pls_golite062009
DNA binding 0.795215102771438 bayes_pls_golite062009
protein binding 0.507853039018204 bayes_pls_golite062009
transcription factor activity 0.31058772088671 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [368-443] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNIKTGSQSA EQKTSNNPHS RLFKVVLTIW HYSEILLLIM GIYLFSACIR VFQRRFKKIR  60
   61 SRRKRAGSHS VGLLPM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle