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View Structure Prediction Details

Protein: SAP190
Organism: Saccharomyces cerevisiae
Length: 1098 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAP190.

Description E-value Query
Range
Subject
Range
SAP190 - Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; me...
0.0 [1..1098] [1..1098]
gi|6179410 - gi|6179410|emb|CAB59918.1| hypothetical phosphatase associated protein [Candida albicans]
0.0 [1..768] [1..708]
gi|119595117, gi... - gi|13489083|ref|NP_060782.2| SAPS domain family, member 3 [Homo sapiens], gi|119595118|gb|EAW74712.1...
0.0 [319..993] [44..709]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSFWKFGQ DYSIESPVSK ILNSAFIKIN KDQDDDVPTG TCEENIADDE DNSSHDYAAS  60
   61 EDNVVNENEE KEEENTLPTT ESEYENYR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.858 0.922 G1/S transition of mitotic cell cycle a.74.1 Cyclin-like
View Download 0.469 0.922 G1/S transition of mitotic cell cycle a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.858 0.922 G1/S transition of mitotic cell cycle a.74.1 Cyclin-like
View Download 0.763 0.922 G1/S transition of mitotic cell cycle a.74.1 Cyclin-like
View Download 0.609 0.922 G1/S transition of mitotic cell cycle a.74.1 Cyclin-like
View Download 0.607 0.922 G1/S transition of mitotic cell cycle a.74.1 Cyclin-like
View Download 0.469 0.922 G1/S transition of mitotic cell cycle a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.458 0.922 G1/S transition of mitotic cell cycle a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.458 0.922 G1/S transition of mitotic cell cycle d.188.1 Prokaryotic ribosomal protein L17
View Download 0.451 0.922 G1/S transition of mitotic cell cycle a.46.1 Methionine synthase domain
View Download 0.363 0.922 G1/S transition of mitotic cell cycle a.35.1 lambda repressor-like DNA-binding domains
View Download 0.357 0.922 G1/S transition of mitotic cell cycle a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.312 0.922 G1/S transition of mitotic cell cycle c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.312 0.922 G1/S transition of mitotic cell cycle a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.312 0.922 G1/S transition of mitotic cell cycle a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.308 0.922 G1/S transition of mitotic cell cycle a.4.5 "Winged helix" DNA-binding domain
View Download 0.305 0.922 G1/S transition of mitotic cell cycle a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.305 0.922 G1/S transition of mitotic cell cycle a.4.5 "Winged helix" DNA-binding domain
View Download 0.296 0.922 G1/S transition of mitotic cell cycle a.64.1 Saposin
View Download 0.288 0.922 G1/S transition of mitotic cell cycle d.211.1 Ankyrin repeat
View Download 0.248 0.922 G1/S transition of mitotic cell cycle d.52.1 Alpha-lytic protease prodomain
View Download 0.203 0.922 G1/S transition of mitotic cell cycle a.74.1 Cyclin-like

Predicted Domain #2
Region A:
Residues: [89-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNLDVLDDLL DDDELYTELM CSNFKLLIFL KYPDVLSKLI EYVTNEKILD EETDSAKKPE  60
   61 IIEGVNDHPI LIERDRKDKK EDAEEGGDSE ETTNDSDHDS GDERSVDSEE TSITLPPESE 120
  121 EQVETRRARI AAEILSADVW PISAAIMQNK DLLGRLWSIL DHPAPLPIPA STYFMKINER 180
  181 LLDMDITGML EFILSRDSLV ARFLTHVDNP SLMDFLLKVI STDKPDSPTG VIKILKSQEL 240
  241 IPKLLDHLNP EYGISTQSAA GDFIKAFVTL STNSSNELAS GIGPNELTRQ LVSEEMIEKL 300
  301 IKIMLKGGTS LSNGVGIIIE LIRKNNSDYD FIQLVYTTLE SHPPTDRDPI HLIHLVKLFA 360
  361 KHMPDFADML DKTKLPLMEM PFGNIEPLGF ERFKICELIA ELLHCSNMTL LNEPNGEMIA 420
  421 QERDIERAKE LETSTEKENI TAIVDNKSSY YDKDCVEKDI TENLGALQIN NQGSEEDELN 480
  481 DTGVSSVKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.237 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore

Predicted Domain #3
Region A:
Residues: [578-770]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVKSDAKVVE GLENDASGVE LYDETLSDTE SVRECLREKP LVGDRLKIAL EDTKILISIL  60
   61 DMFTEFPWNN FLHNVIFDIA QQIFNGPLKT GYNRFLLKDY LVDAYLTKKI VDADKACQDY 120
  121 EKKTGLRYGY MGHLTLVAEE ISKFKEYIDE MKLTFCNTAV SDRLEEPFWK EYSETILADT 180
  181 REKYNTVLGD FGN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [771-1003]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQESDDDVIR NSDSEDIIGD TEGNENYGNG ENDELLSNGH DSGNMDLYYN FNNNENEENE  60
   61 EDYAEYSDVD NKNYYNNVET NDDDYDSDDG KSKSAESEFT DKISEHRDGN SLYNEDNDEN 120
  121 GSDKWTSGTS LFPPDHFPSR SQPSDPKLQD QNIFHHQFDF EGVGDDDDYM DPNDDGQSYA 180
  181 RPGNPLYTTP KTPPRPKTIL FNSLSALDNN GEDEEVALGT SVDDRMDNEI SSD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1004-1098]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEDSEMKMKR MIWAMRRATH YIGQEVKKLS ELKHSHCHIF TLYSSIFYCS TFFAYRSFII  60
   61 HQIYTFLIEA CNLILTEYNL IKNNEYSLLN ILKFI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.820 0.006 protein serine/threonine phosphatase activity a.7.7 BAG domain
View Download 0.813 0.006 protein serine/threonine phosphatase activity a.7.5 Tubulin chaperone cofactor A
View Download 0.868 0.006 protein serine/threonine phosphatase activity a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.832 0.006 protein serine/threonine phosphatase activity a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.820 0.006 protein serine/threonine phosphatase activity a.7.6 Ribosomal protein S20
View Download 0.811 0.006 protein serine/threonine phosphatase activity a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit
View Download 0.774 0.006 protein serine/threonine phosphatase activity a.60.9 lambda integrase-like, N-terminal domain
View Download 0.691 0.006 protein serine/threonine phosphatase activity a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.689 0.006 protein serine/threonine phosphatase activity f.15.1 Small-conductance potassium channel
View Download 0.688 0.006 protein serine/threonine phosphatase activity a.47.2 t-snare proteins
View Download 0.662 0.006 protein serine/threonine phosphatase activity a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.656 0.006 protein serine/threonine phosphatase activity a.25.1 Ferritin-like
View Download 0.601 0.006 protein serine/threonine phosphatase activity a.118.1 ARM repeat
View Download 0.599 0.006 protein serine/threonine phosphatase activity a.7.1 Spectrin repeat
View Download 0.554 0.006 protein serine/threonine phosphatase activity f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.540 0.006 protein serine/threonine phosphatase activity a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.538 0.006 protein serine/threonine phosphatase activity a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.538 0.006 protein serine/threonine phosphatase activity a.133.1 Phospholipase A2, PLA2
View Download 0.534 0.006 protein serine/threonine phosphatase activity d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.531 0.006 protein serine/threonine phosphatase activity a.64.1 Saposin
View Download 0.527 0.006 protein serine/threonine phosphatase activity i.11.1 Computational models partly based on NMR data
View Download 0.496 0.006 protein serine/threonine phosphatase activity a.24.9 alpha-catenin/vinculin
View Download 0.494 0.006 protein serine/threonine phosphatase activity a.64.1 Saposin
View Download 0.492 0.006 protein serine/threonine phosphatase activity a.39.1 EF-hand
View Download 0.488 0.006 protein serine/threonine phosphatase activity a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.480 0.006 protein serine/threonine phosphatase activity a.74.1 Cyclin-like
View Download 0.452 0.006 protein serine/threonine phosphatase activity a.118.8 TPR-like
View Download 0.445 0.006 protein serine/threonine phosphatase activity a.77.1 DEATH domain
View Download 0.433 0.006 protein serine/threonine phosphatase activity f.13.1 Family A G protein-coupled receptor-like
View Download 0.428 0.006 protein serine/threonine phosphatase activity a.7.1 Spectrin repeat
View Download 0.426 0.006 protein serine/threonine phosphatase activity a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.420 0.006 protein serine/threonine phosphatase activity a.24.14 FAT domain of focal adhesion kinase
View Download 0.420 0.006 protein serine/threonine phosphatase activity a.24.17 Group V grass pollen allergen
View Download 0.417 0.006 protein serine/threonine phosphatase activity a.2.7 tRNA-binding arm
View Download 0.416 0.006 protein serine/threonine phosphatase activity i.1.1 Ribosome and ribosomal fragments
View Download 0.414 0.006 protein serine/threonine phosphatase activity f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.381 0.006 protein serine/threonine phosphatase activity d.95.2 Homing endonucleases
View Download 0.379 0.006 protein serine/threonine phosphatase activity a.126.1 Serum albumin-like
View Download 0.372 0.006 protein serine/threonine phosphatase activity a.118.9 ENTH/VHS domain
View Download 0.371 0.006 protein serine/threonine phosphatase activity a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.371 0.006 protein serine/threonine phosphatase activity a.2.7 tRNA-binding arm
View Download 0.353 0.006 protein serine/threonine phosphatase activity a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.351 0.006 protein serine/threonine phosphatase activity a.66.1 Transducin (alpha subunit), insertion domain
View Download 0.349 0.006 protein serine/threonine phosphatase activity b.82.3 cAMP-binding domain-like
View Download 0.347 0.006 protein serine/threonine phosphatase activity c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.344 0.006 protein serine/threonine phosphatase activity a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.343 0.006 protein serine/threonine phosphatase activity a.60.9 lambda integrase-like, N-terminal domain
View Download 0.339 0.006 protein serine/threonine phosphatase activity a.39.1 EF-hand
View Download 0.338 0.006 protein serine/threonine phosphatase activity d.54.1 Enolase N-terminal domain-like
View Download 0.337 0.006 protein serine/threonine phosphatase activity a.59.1 PAH2 domain
View Download 0.316 0.006 protein serine/threonine phosphatase activity a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.312 0.006 protein serine/threonine phosphatase activity a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.301 0.006 protein serine/threonine phosphatase activity a.4.12 TrpR-like
View Download 0.298 0.006 protein serine/threonine phosphatase activity a.7.7 BAG domain
View Download 0.297 0.006 protein serine/threonine phosphatase activity d.110.4 SNARE-like
View Download 0.297 0.006 protein serine/threonine phosphatase activity a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.291 0.006 protein serine/threonine phosphatase activity a.72.1 Functional domain of the splicing factor Prp18
View Download 0.290 0.006 protein serine/threonine phosphatase activity a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.290 0.006 protein serine/threonine phosphatase activity a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.286 0.006 protein serine/threonine phosphatase activity a.74.1 Cyclin-like
View Download 0.284 0.006 protein serine/threonine phosphatase activity a.112.1 Description not found.
View Download 0.283 0.006 protein serine/threonine phosphatase activity a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.282 0.006 protein serine/threonine phosphatase activity a.7.5 Tubulin chaperone cofactor A
View Download 0.279 0.006 protein serine/threonine phosphatase activity a.24.4 Hemerythrin
View Download 0.278 0.006 protein serine/threonine phosphatase activity a.35.1 lambda repressor-like DNA-binding domains
View Download 0.278 0.006 protein serine/threonine phosphatase activity a.4.5 "Winged helix" DNA-binding domain
View Download 0.271 0.006 protein serine/threonine phosphatase activity a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.267 0.006 protein serine/threonine phosphatase activity a.24.17 Group V grass pollen allergen
View Download 0.267 0.006 protein serine/threonine phosphatase activity a.24.3 Cytochromes
View Download 0.263 0.006 protein serine/threonine phosphatase activity a.26.1 4-helical cytokines
View Download 0.262 0.006 protein serine/threonine phosphatase activity a.29.2 Bromodomain
View Download 0.261 0.006 protein serine/threonine phosphatase activity a.2.7 tRNA-binding arm
View Download 0.261 0.006 protein serine/threonine phosphatase activity a.24.3 Cytochromes
View Download 0.261 0.006 protein serine/threonine phosphatase activity a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.260 0.006 protein serine/threonine phosphatase activity a.16.1 S15/NS1 RNA-binding domain
View Download 0.255 0.006 protein serine/threonine phosphatase activity a.142.1 PTS-regulatory domain, PRD
View Download 0.255 0.006 protein serine/threonine phosphatase activity a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.251 0.006 protein serine/threonine phosphatase activity a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.249 0.006 protein serine/threonine phosphatase activity a.24.3 Cytochromes
View Download 0.249 0.006 protein serine/threonine phosphatase activity d.45.1 ClpS-like
View Download 0.246 0.006 protein serine/threonine phosphatase activity a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.244 0.006 protein serine/threonine phosphatase activity d.79.1 YjgF-like
View Download 0.242 0.006 protein serine/threonine phosphatase activity f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.241 0.006 protein serine/threonine phosphatase activity a.74.1 Cyclin-like
View Download 0.237 0.006 protein serine/threonine phosphatase activity a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.236 0.006 protein serine/threonine phosphatase activity a.61.1 Retroviral matrix proteins
View Download 0.235 0.006 protein serine/threonine phosphatase activity a.4.5 "Winged helix" DNA-binding domain
View Download 0.235 0.006 protein serine/threonine phosphatase activity a.4.5 "Winged helix" DNA-binding domain
View Download 0.234 0.006 protein serine/threonine phosphatase activity d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.234 0.006 protein serine/threonine phosphatase activity d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.233 0.006 protein serine/threonine phosphatase activity a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.228 0.006 protein serine/threonine phosphatase activity d.54.1 Enolase N-terminal domain-like
View Download 0.226 0.006 protein serine/threonine phosphatase activity a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.226 0.006 protein serine/threonine phosphatase activity a.29.4 RecG, N-terminal domain
View Download 0.225 0.006 protein serine/threonine phosphatase activity f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.225 0.006 protein serine/threonine phosphatase activity a.156.1 S13-like H2TH domain
View Download 0.225 0.006 protein serine/threonine phosphatase activity a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.224 0.006 protein serine/threonine phosphatase activity a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.222 0.006 protein serine/threonine phosphatase activity a.23.5 Hemolysin expression modulating protein HHA
View Download 0.222 0.006 protein serine/threonine phosphatase activity a.77.1 DEATH domain
View Download 0.221 0.006 protein serine/threonine phosphatase activity g.44.1 RING/U-box
View Download 0.221 0.006 protein serine/threonine phosphatase activity a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.221 0.006 protein serine/threonine phosphatase activity a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.221 0.006 protein serine/threonine phosphatase activity a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.219 0.006 protein serine/threonine phosphatase activity a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.218 0.006 protein serine/threonine phosphatase activity d.189.1 PX domain
View Download 0.216 0.006 protein serine/threonine phosphatase activity a.60.1 SAM/Pointed domain
View Download 0.215 0.006 protein serine/threonine phosphatase activity a.2.7 tRNA-binding arm
View Download 0.215 0.006 protein serine/threonine phosphatase activity d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.211 0.006 protein serine/threonine phosphatase activity d.8.1 Urease, gamma-subunit
View Download 0.204 0.006 protein serine/threonine phosphatase activity a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.204 0.006 protein serine/threonine phosphatase activity a.61.1 Retroviral matrix proteins
View Download 0.204 0.006 protein serine/threonine phosphatase activity a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.200 0.006 protein serine/threonine phosphatase activity a.51.1 Cytochrome c oxidase subunit h

Predicted Domain #6
Region A:
Residues: [776-1098]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDVIRNSDSE DIIGDTEGNE NYGNGENDEL LSNGHDSGNM DLYYNFNNNE NEENEEDYAE  60
   61 YSDVDNKNYY NNVETNDDDY DSDDGKSKSA ESEFTDKISE HRDGNSLYNE DNDENGSDKW 120
  121 TSGTSLFPPD HFPSRSQPSD PKLQDQNIFH HQFDFEGVGD DDDYMDPNDD GQSYARPGNP 180
  181 LYTTPKTPPR PKTILFNSLS ALDNNGEDEE VALGTSVDDR MDNEISSDEE DSEMKMKRMI 240
  241 WAMRRATHYI GQEVKKLSEL KHSHCHIFTL YSSIFYCSTF FAYRSFIIHQ IYTFLIEACN 300
  301 LILTEYNLIK NNEYSLLNIL KFI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1ux6A
Description: Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle