YRC Public Data Repository - Protein Structure Prediction

Protein:	SAC1
Organism:	Saccharomyces cerevisiae
Length:	623 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAC1.

Description	E-value	Query Range	Subject Range
SAC1_YEAST - Phosphoinositide phosphatase SAC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAC1 P... gi\|151941452 - gi\|151941452\|gb\|EDN59816.1\| phosphoinositide phosphatase [Saccharomyces cerevisiae YJM789] gi\|190409635 - gi\|190409635\|gb\|EDV12900.1\| phosphoinositide phosphatase [Saccharomyces cerevisiae RM11-1a] SAC1 - Phosphatidylinositol phosphate (PtdInsP) phosphatase involved in hydrolysis of PtdIns[4]P; transmemb...	0.0	[1..623]	[1..623]
SAC1_RAT - Phosphatidylinositide phosphatase SAC1 OS=Rattus norvegicus GN=Sacm1l PE=1 SV=1	0.0	[15..586]	[18..581]
gi\|16741488 - gi\|16741488\|gb\|AAH16559.1\| SAC1 suppressor of actin mutations 1-like (yeast) [Homo sapiens]	0.0	[15..586]	[18..581]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[15..586]	[18..581]
SAC1_MOUSE - Phosphatidylinositide phosphatase SAC1 OS=Mus musculus GN=Sacm1l PE=1 SV=1	0.0	[15..586]	[18..581]
SAC7_ARATH - Phosphoinositide phosphatase SAC7 OS=Arabidopsis thaliana GN=SAC7 PE=2 SV=1	0.0	[16..585]	[23..592]
SPBC19F5.03 - inositol polyphosphate phosphatase YG23_SCHPO - Uncharacterized protein C19F5.03 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC19F5....	0.0	[24..591]	[15..575]

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Predicted Domain #1

Region A:
Residues: [1-375]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGPIVYVQN ADGIFFKLAE GKGTNDAVIH LANQDQGVRV LGAEEFPVQG EVVKIASLMG  60
   61 FIKLKLNRYA IIANTVEETG RFNGHVFYRV LQHSIVSTKF NSRIDSEEAE YIKLLELHLK 120
  121 NSTFYFSYTY DLTNSLQRNE KVGPAASWKT ADERFFWNHY LTEDLRNFAH QDPRIDSFIQ 180
  181 PVIYGYAKTV DAVLNATPIV LGLITRRSIF RAGTRYFRRG VDKDGNVGNF NETEQILLAE 240
  241 NPESEKIHVF SFLQTRGSVP IYWAEINNLK YKPNLVLGEN SLDATKKHFD QQKELYGDNY 300
  301 LVNLVNQKGH ELPVKEGYES VVHALNDPKI HYVYFDFHHE CRKMQWHRVK LLIDHLEKLG 360
  361 LSNEDFFHKV IDSNG

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	157.853872
Match:	PF02383
Description:	SacI homology domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [376-623]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTVEIVNEQH SVVRTNCMDC LDRTNVVQSV LAQWVLQKEF ESADVVATGS TWEDNAPLLT  60
   61 SYQNLWADNA DAVSVAYSGT GALKTDFTRT GKRTRLGAFN DFLNSASRYY QNNWTDGPRQ 120
  121 DSYDLFLGGF RPHTASIKSP FPDRRPVYIQ LIPMIICAAL TVLGATIFFP KDRFTSSKNL 180
  181 LYFAGASIVL ALSTKFMFKN GIQFVNWPKL VDVGFLVVHQ THDKEQQFKG LKYAQSPKFS 240
  241 KPDPLKRD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits