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View Structure Prediction Details

Protein: LOS1
Organism: Saccharomyces cerevisiae
Length: 1100 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LOS1.

Description E-value Query
Range
Subject
Range
XPOT_YEAST - Exportin-T OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LOS1 PE=1 SV=1
LOS1 - Nuclear pore protein involved in nuclear export of pre-tRNA and in re-export of mature tRNAs after t...
0.0 [1..1100] [1..1100]
XPOT - exportin, tRNA (nuclear export receptor for tRNAs)
0.0 [14..1087] [10..952]
XPOT_SCHPO - Exportin-T OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=los1 PE=1 SV=1
SPBP8B7.09c - karyopherin
0.0 [2..1099] [3..976]
xpo-3 - importin beta, nuclear transport factor status:Partially_confirmed UniProt:Q9GYQ7 protein_id:AAF9989...
0.0 [17..843] [13..757]
IPO13_RAT - Importin-13 OS=Rattus norvegicus GN=Ipo13 PE=2 SV=1
2.0E-81 [3..871] [24..786]

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Predicted Domain #1
Region A:
Residues: [1-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLERIQQLVN AVNDPRSDVA TKRQAIELLN GIKSSENALE IFISLVINEN SNDLLKFYGL  60
   61 STLIELMTEG VNANPNGLNL VKFEITKWLK FQVLGNKQTK LPDFLMNKIS EVLTTLFMLM 120
  121 YSDCNGNQWN SFFDDLMSLF QVDSAISNTS PSTDGNILLG LEFFNKLCLM INSEIADQSF 180
  181 IRSKESQLKN NNIKDWMRDN DIMKLSNVWF QCLKLDEQIV SQCPGLINST LDCIGSFISW 240
  241 IDINLIIDAN NYYLQLIYKF LNLKETKISC YNCILAIISK KMKPMDKLAF LNMINLTNEL 300
  301 TYYHQAISMN PQIITFDNLE VWESLTKLIT SFGIEFTIII EQVNDDQKLD TLYKQSVISN 360
  361 VDSILLEKII PILLEFMNNE FDSITAKTFP FWSNYLAFLK KYKASSPNFV PLHKDFLDNF 420
  421 QQICFKRMKF SDDE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [435-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTQDDFEEFN ETVRFKLKNF QEIIVVIDPS LFLNNISQEI SANLMNCKNE SWQIFELTIY  60
   61 QIFNLSECTK NNYFGLNKNE IM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.917 0.008 tRNA splicing, via endonucleolytic cleavage and ligation a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3

Predicted Domain #3
Region A:
Residues: [517-1100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSQPSLTLVR FLNELLMMKD FLLAIDNEQI QILFMELIVK NYNFIFSTSA NTANATDDDE  60
   61 KYLLILNIFM SSFAMFNKRE NVRLRSWYLF TRFLKLTRIN LKKILFANKN LVNEITNKIS 120
  121 PLLHIKVTSI NAQGTDDNDT IFDNQLYIFE GIGFIITLNN SSQELTAATA NTPIDYDILD 180
  181 QILTPLFTQL EGCITQGASP VVILECHHIL MAIGTLARGL HIGLVPENQV NNMVVNKKLI 240
  241 NDSLIHKFSN IAEVILVTFS FFNKFENIRD ASRFTFARLI PILSNKILPF INKLIELILS 300
  301 STDLKSWEMI DFLGFLSQLI HMFHTDTDCY QLFNQLLTPL INKVHSIIEE IDEQHDQQSS 360
  361 SNKPIDTAVT ATSVNKNIVV TDSYRDKILL KKAYCTFLQS FTNNSVTSIL LSDINRAILP 420
  421 VILNDLVTYT PQEIQETSMM KVSLNVLCNF IKCFGNGTCL DNDDINKDPN LKIDGLNEYF 480
  481 IMKCVPIIFE IPFNPIYKFN IKEGNFKTMA YDLARLLREL FIVSSNPTTN ENECVKYLTQ 540
  541 IYLPQIQLPQ ELTIQLVNML TTMGQKQFEK WFVDNFISVL KQGQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1013-1100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKFNIKEGNF KTMAYDLARL LRELFIVSSN PTTNENECVK YLTQIYLPQI QLPQELTIQL  60
   61 VNMLTTMGQK QFEKWFVDNF ISVLKQGQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle