YRC Public Data Repository - Protein Structure Prediction

Protein:	YKL151C
Organism:	Saccharomyces cerevisiae
Length:	337 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKL151C.

Description	E-value	Query Range	Subject Range
YKL151C - Putative protein of unknown function; YKL151C promoter contains STREs (stress response elements) and... NNRD_YEAST - ATP-dependent (S)-NAD(P)H-hydrate dehydratase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288... gi\|190409688 - gi\|190409688\|gb\|EDV12953.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]	4.0E-67	[1..337]	[1..337]
gi\|18145000, gi\|... - gi\|18310320\|ref\|NP_562254.1\| phosphomethylpyrimidine kinase [Clostridium perfringens str. 13], gi\|18...	7.0E-51	[35..295]	[7..258]
gi\|25326092 - pir\|\|F97951 phosphomethylpyrimidine kinase (EC 2.7.4.7) [imported] - Streptococcus pneumoniae (strai... gi\|15458222, gi\|... - gi\|15902682\|ref\|NP_358232.1\| phosphomethylpyrimidine kinase [Streptococcus pneumoniae R6], gi\|154582... gi\|237821850 - gi\|237821850\|ref\|ZP_04597695.1\| phosphomethylpyrimidine kinase [Streptococcus pneumoniae CCRI 1974M2... gi\|237651010 - gi\|237651010\|ref\|ZP_04525262.1\| phosphomethylpyrimidine kinase [Streptococcus pneumoniae CCRI 1974] gi\|116077129, gi... - gi\|116516553\|ref\|YP_816128.1\| phosphomethylpyrimidine kinase [Streptococcus pneumoniae D39], gi\|1160...	3.0E-50	[33..294]	[5..256]
gi\|15900623, gi\|... - gi\|66878133\|ref\|ZP_00403632.1\| COG0351: Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Stre... gi\|25326080 - pir\|\|B95084 phosphomethylpyrimidine kinase [imported] - Streptococcus pneumoniae (strain TIGR4) gi\|225728252, gi... - gi\|225860704\|ref\|YP_002742213.1\| phosphomethylpyrimidine kinase [Streptococcus pneumoniae Taiwan19F-...	3.0E-50	[33..294]	[5..256]
gi\|25326086 - pir\|\|H97280 hydroxyethylthiazole kinase ThiM/ThiK (FS1) CAC3095 [imported] - Clostridium acetobutyli... gi\|15896346, gi\|... - gi\|15896346\|ref\|NP_349695.1\| hydroxyethylthiazole kinase ThiM/ThiK (FS!) [Clostridium acetobutylicum...	7.0E-50	[34..295]	[6..257]
gi\|15603126, gi\|... - gi\|15603126\|ref\|NP_246198.1\| phosphomethylpyrimidine kinase [Pasteurella multocida subsp. multocida ...	7.0E-49	[31..293]	[3..259]
gi\|269203729\|ref... - phosphomethylpyrimidine kinase [Staphylococcus aureus subsp. aureus ED98] THID_STAAM - Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase OS=Staphylococcus aureus (strain Mu50 / ATCC ... gi\|156722544, gi... - gi\|156980409\|ref\|YP_001442668.1\| phosphomethylpyrimidine kinase [Staphylococcus aureus subsp. aureus... THID_STAAN - Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase OS=Staphylococcus aureus (strain N315) GN=thi... gi\|90583378, gi\|... - gi\|90583378\|ref\|ZP_01239135.1\| Phosphomethylpyrimidine kinase [Staphylococcus aureus subsp. aureus J... gi\|25326087 - pir\|\|C90002 phosphomethylpyrimidine kinase [imported] - Staphylococcus aureus (strain N315) gi\|90585700, gi\|... - gi\|90585700\|ref\|ZP_01241408.1\| Phosphomethylpyrimidine kinase [Staphylococcus aureus subsp. aureus J... gi\|255006882 - gi\|255006882\|ref\|ZP_05145483.2\| phosphomethylpyrimidine kinase [Staphylococcus aureus subsp. aureus ...	9.0E-49	[35..294]	[7..259]
SPBP8B7.18c - phosphomethylpyrimidine kinase THI22_SCHPO - Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2 OS=Schizosaccharomyces pombe (stra...	1.0E-48	[28..288]	[31..300]
gi\|88191074, gi\|... - gi\|88596233\|ref\|ZP_01099470.1\| phosphomethylpyrimidine kinase [Campylobacter jejuni subsp. jejuni 84... gi\|11280145 - pir\|\|E81311 phosphomethylpyrimidine kinase (EC 2.7.4.7) Cj1082c [imported] - Campylobacter jejuni (s... gi\|15792407, gi\|... - gi\|6968516\|emb\|CAB73337.1\| phosphomethylpyrimidine kinase [Campylobacter jejuni subsp. jejuni NCTC 1...	4.0E-48	[35..293]	[11..259]

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Predicted Domain #1

Region A:
Residues: [1-337]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAELSHREL IKLAQKRCIP PLLPKFHKGQ SGGRVCIIGG CEDYTGAPYF SANATALMGC  60
   61 DLTHVICEYN AGTVIKSYTP NLMVHPYLRM SNTKLDVDMD EQRKKINSLL DRIHVVVIGP 120
  121 GLGRDPLMLK SIKDIIRYIL EKHEGKIPLV IDADGLFLVT QDSEVKEMLK SYPKGRVILT 180
  181 PNVVEFKRLC DAIGKKGDSH SEMGSLIAQE LNCIVVEKGQ SDKIFSPDSE KDMLTNSEEG 240
  241 SNKRVGGQGD TLTGAISCML AFSRAMYDFK ICEQEEKGES SNDKPLKNWV DYAMLSCYAG 300
  301 CTITRECSRL GFKAKGRAMQ TTDLNDRVGE VFAKLFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.221849
Match:	1lljA_
Description:	No description for 1lljA_ was found.

Predicted functions:

Term	Confidence	Notes
kinase activity	2.21989077746778	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.18210652956301	bayes_pls_golite062009
transferase activity	1.93919655638959	bayes_pls_golite062009
catalytic activity	1.20214183637432	bayes_pls_golite062009
carbohydrate kinase activity	0.763172169813799	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.673555832721854	bayes_pls_golite062009
binding	0.227903661692164	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: