| Protein: | TGL1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 548 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TGL1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..548] | [1..548] |
|
|
3.0E-89 | [59..417] | [27..392] |
|
|
5.0E-89 | [59..417] | [27..392] |
|
Region A: Residues: [1-463] |
1 11 21 31 41 51
| | | | | |
1 MYFPFLGRLS ITDYIIVVLV YIESIISSVL KLIPQPMINL FEWLINFSTS SDDNTIEEKL 60
61 RSAPTIHEMC AIFDISVEDH LVRTEDNYIL TLHRIPPISK NRFNNKVVYL HHGLLMCSDV 120
121 WCCNIERHKN LPFVLHDLGY DVWMGNNRGN KYSTAHLNKP PKSNKFWDFS IDEFAFFDIP 180
181 NSIEFILDIT KVDKVICIGF SQGSAQMFAA FSLSEKLNRK VSHFIAIAPA MTPKGLHNRI 240
241 VDTLAKSSPG FMYLFFGRKI VLPSAVIWQR TLHPTLFNLC IDIANKILFN WKSFNILPRQ 300
301 KIASYAKLYS TTSVKSIVHW FQILRSQKFQ MFEESDNMLN SLTRPYQIAN FPTRTNIKIP 360
361 ILLIYGGIDS LVDIDVMKKN LPFNSVFDVK VDNYEHLDLI WGKDADTLVI AKVLRFIEFF 420
421 NPGNVSVKTN QLLPSASLVE ELPSTTWKTT HPTHGLSYRT HSA
|
| Detection Method: |  |
| Confidence: | 526.554485 |
| Match: | 1k8qA_ |
| Description: | Gastric lipase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| hydrolase activity | 3.20549979663539 | bayes_pls_golite062009 |
| malate dehydrogenase activity | 2.28093794718528 | bayes_pls_golite062009 |
| palmitoyl-(protein) hydrolase activity | 2.14423515928317 | bayes_pls_golite062009 |
| catalytic activity | 1.39629727416851 | bayes_pls_golite062009 |
| triglyceride lipase activity | 1.2959733599348 | bayes_pls_golite062009 |
| sterol esterase activity | 1.21262745914703 | bayes_pls_golite062009 |
| thiolester hydrolase activity | 1.18565704009692 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 0.985235528680562 | bayes_pls_golite062009 |
| palmitoyl-CoA hydrolase activity | 0.92549140936125 | bayes_pls_golite062009 |
| peptidase activity | 0.858311047004898 | bayes_pls_golite062009 |
| lipase activity | 0.849473630399459 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 0.590445773074315 | bayes_pls_golite062009 |
| carboxylesterase activity | 0.424330502936163 | bayes_pls_golite062009 |
| binding | 0.351031277062254 | bayes_pls_golite062009 |
|
Region A: Residues: [464-548] |
1 11 21 31 41 51
| | | | | |
1 DRSPLSVQAD EADEVHNADN SRFLRRVFST SAIDEDNENE HQDDTEDQIH KEQQRRLSAY 60
61 LESSKDLRQL DANSSTTALD ALNKE
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.355 | a.64.1 | Saposin |
| View | Download | 0.546 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.384 | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.486 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.377 | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.546 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.486 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.384 | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.377 | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.355 | a.64.1 | Saposin |
| View | Download | 0.351 | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.342 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.310 | a.2.3 | Chaperone J-domain |
| View | Download | 0.287 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.286 | a.24.3 | Cytochromes |
| View | Download | 0.280 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.269 | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.268 | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.248 | a.24.4 | Hemerythrin |
| View | Download | 0.245 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.240 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.238 | a.77.1 | DEATH domain |
| View | Download | 0.223 | a.2.3 | Chaperone J-domain |
| View | Download | 0.223 | a.64.1 | Saposin |
| View | Download | 0.222 | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.221 | a.26.1 | 4-helical cytokines |
| View | Download | 0.219 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.209 | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.200 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
