YRC Public Data Repository - Protein Structure Prediction

Protein:	OCT1
Organism:	Saccharomyces cerevisiae
Length:	770 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OCT1.

Description	E-value	Query Range	Subject Range
PMIP_YEAST - Mitochondrial intermediate peptidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OCT... OCT1 - Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon impor...	0.0	[1..770]	[1..772]
gi\|194455090, gi... - gi\|194468726\|ref\|ZP_03074710.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Kentuc... gi\|194449661, gi... - gi\|194449661\|ref\|YP_002047620.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Heide... gi\|168241749, gi... - gi\|205338757\|gb\|EDZ25521.1\| peptidase family M3 [Salmonella enterica subsp. enterica serovar Heidelb... gi\|168235191, gi... - gi\|197291259\|gb\|EDY30611.1\| peptidase family M3 [Salmonella enterica subsp. enterica serovar Schwarz... gi\|205354788, gi... - gi\|205354788\|ref\|YP_002228589.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Galli... gi\|200386491, gi... - gi\|200386491\|ref\|ZP_03213103.1\| peptidase family M3 [Salmonella enterica subsp. enterica serovar Vir... gi\|198246092, gi... - gi\|198246092\|ref\|YP_002217553.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Dubli... gi\|194734493, gi... - gi\|194734493\|ref\|YP_002116530.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Schwa... OPDA_SALTY - Oligopeptidase A OS=Salmonella typhimurium GN=prlC PE=1 SV=1 gi\|205333223, gi... - gi\|205333223\|gb\|EDZ19987.1\| peptidase family M3 [Salmonella enterica subsp. enterica serovar Kentuck... gi\|205330668, gi... - gi\|205330668\|gb\|EDZ17432.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar 4,[5],12:i... gi\|167549185, gi... - gi\|205325717\|gb\|EDZ13556.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Saintpaul ... gi\|161366009, gi... - gi\|161616645\|ref\|YP_001590610.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Parat... gi\|238910378 - gi\|238910378\|ref\|ZP_04654215.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Tennes... lcl\|NC_016856.1_... - [gene=prlC] [protein=oligopeptidase A] [protein_id=YP_005239807.1] [location=complement(3777641..377... OPDA_SALTY - Oligopeptidase A OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=prlC PE=1 SV=1 OPDA_SALTY - Oligopeptidase A OS=Salmonella typhimurium GN=prlC PE=1 SV=1	0.0	[80..757]	[3..677]
gi\|213053405 - gi\|213053405\|ref\|ZP_03346283.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Typhi ... gi\|213425056 - gi\|213425056\|ref\|ZP_03357806.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Typhi ... gi\|213999891 - gi\|213999891\|ref\|ZP_03410626.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Typhi ... gi\|16762706 - gi\|16762706\|ref\|NP_458323.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Typhi str... gi\|16505012, gi\|... - gi\|25319699\|pir\|\|AB0988 oligopeptidase A (EC 3.4.24.70) [imported] - Salmonella enterica subsp. ente... gi\|29144193, gi\|... - gi\|29144193\|ref\|NP_807535.1\| oligopeptidase A [Salmonella enterica subsp. enterica serovar Typhi str...	0.0	[80..757]	[3..677]
gi\|124528584, gi... - gi\|124528584\|ref\|ZP_01699862.1\| Oligopeptidase A [Escherichia coli B], gi\|124500425\|gb\|EAY47898.1\| O... EG11441 - oligopeptidase A / Oligopeptidase A, zinc metalloprotease; involved in the degradation of cleaved si... EG11441 - oligopeptidase A / Oligopeptidase A, zinc metalloprotease; involved in the degradation of cleaved si... gi\|238902587, gi... - gi\|238902587\|ref\|YP_002928383.1\| oligopeptidase A [Escherichia coli BW2952], gi\|238861932\|gb\|ACR6393... gi\|226839176, gi... - gi\|254038670\|ref\|ZP_04872726.1\| oligopeptidase A [Escherichia sp. 1_1_43], gi\|226839176\|gb\|EEH71199.... gi\|89110515, gi\|... - gi\|89110515\|ref\|AP_004295.1\| oligopeptidase A [Escherichia coli str. K-12 substr. W3110], gi\|8567654... gi\|170018272, gi... - gi\|170018272\|ref\|YP_001723226.1\| oligopeptidase A [Escherichia coli ATCC 8739], gi\|169753200\|gb\|ACA7... gi\|75516039, gi\|... - gi\|75516039\|ref\|ZP_00738157.1\| COG0339: Zn-dependent oligopeptidases [Escherichia coli 53638], gi\|18... gi\|75260213, gi\|... - gi\|75260213\|ref\|ZP_00731481.1\| COG0339: Zn-dependent oligopeptidases [Escherichia coli E22], gi\|1930... gi\|170684269, gi... - gi\|170684269\|ref\|YP_001745753.1\| oligopeptidase A [Escherichia coli SMS-3-5], gi\|170521987\|gb\|ACB201... gi\|194414962, gi... - gi\|75211865\|ref\|ZP_00711929.1\| COG0339: Zn-dependent oligopeptidases [Escherichia coli B171], gi\|194... gi\|170083009, gi... - gi\|170083009\|ref\|YP_001732329.1\| oligopeptidase A [Escherichia coli str. K-12 substr. DH10B], gi\|169... OPDA_ECOLI - Oligopeptidase A (EC 3.4.24.70) - Escherichia coli gi\|157162974, gi... - gi\|75197419\|ref\|ZP_00707489.1\| COG0339: Zn-dependent oligopeptidases [Escherichia coli HS], gi\|15716... gi\|218702251, gi... - gi\|218702251\|ref\|YP_002409880.1\| oligopeptidase A [Escherichia coli IAI39], gi\|218372237\|emb\|CAR2009... gi\|209914213, gi... - gi\|209920954\|ref\|YP_002295038.1\| oligopeptidase A [Escherichia coli SE11], gi\|209914213\|dbj\|BAG79287...	0.0	[80..757]	[3..677]
gi\|209396642, gi... - gi\|209396642\|ref\|YP_002272964.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4115], gi\|2091580... gi\|217325564, gi... - gi\|217325564\|ref\|ZP_03441648.1\| oligopeptidase A [Escherichia coli O157:H7 str. TW14588], gi\|2173217... gi\|195935016 - gi\|195935016\|ref\|ZP_03080398.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4024] gi\|208808077, gi... - gi\|208808077\|ref\|ZP_03250414.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4206], gi\|20872787... gi\|208813633, gi... - gi\|208813633\|ref\|ZP_03254962.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4045], gi\|20873491... gi\|208739743, gi... - gi\|208819620\|ref\|ZP_03259940.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4042], gi\|20873974... gi\|168772565, gi... - gi\|187771638\|gb\|EDU35482.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4196], gi\|168772565\|re... gi\|168779626, gi... - gi\|189002260\|gb\|EDU71246.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4076], gi\|168779626\|re... gi\|189374592, gi... - gi\|189374592\|gb\|EDU93008.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC869], gi\|168785348\|ref... gi\|189379996, gi... - gi\|189379996\|gb\|EDU98412.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC508], gi\|168797313\|ref... gi\|168746980, gi... - gi\|188018294\|gb\|EDU56416.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4113], gi\|168746980\|re... gi\|189359131, gi... - gi\|189359131\|gb\|EDU77550.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4401], gi\|168753295\|re... gi\|13363844, gi\|... - gi\|15833624\|ref\|NP_312397.1\| oligopeptidase A [Escherichia coli O157:H7 str. Sakai], gi\|13363844\|dbj... gi\|189369485, gi... - gi\|189369485\|gb\|EDU87901.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4501], gi\|168759566\|re... gi\|168765890, gi... - gi\|189364810\|gb\|EDU83229.1\| oligopeptidase A [Escherichia coli O157:H7 str. EC4486], gi\|168765890\|re... gi\|13363844, gi\|... - gi\|15833624\|ref\|NP_312397.1\| oligopeptidase A [Escherichia coli O157:H7], gi\|13363844\|dbj\|BAB37793.1... gi\|254795441, gi... - gi\|254795441\|ref\|YP_003080278.1\| oligopeptidase A [Escherichia coli O157:H7 str. TW14359], gi\|254594... gi\|25319707, gi\|... - pir\|\|B91175 oligopeptidase A [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952)... gi\|15804033, gi\|... - gi\|15804033\|ref\|NP_290069.1\| oligopeptidase A [Escherichia coli O157:H7 EDL933], gi\|12518192\|gb\|AAG5...	0.0	[80..757]	[3..677]
gi\|153818548, gi... - gi\|153818548\|ref\|ZP_01971215.1\| oligopeptidase A [Vibrio cholerae NCTC 8457], gi\|126510887\|gb\|EAZ734... gi\|153821596, gi... - gi\|153821596\|ref\|ZP_01974263.1\| oligopeptidase A [Vibrio cholerae B33], gi\|126520883\|gb\|EAZ78106.1\| ... gi\|254847022, gi... - gi\|75830234\|ref\|ZP_00759516.1\| COG0339: Zn-dependent oligopeptidases [Vibrio cholerae MO10], gi\|2548... gi\|15640218, gi\|... - gi\|9654593\|gb\|AAF93364.1\| oligopeptidase A [Vibrio cholerae O1 biovar El Tor str. N16961], gi\|156402... gi\|11355739 - pir\|\|C82353 oligopeptidase A VC0188 [imported] - Vibrio cholerae (strain N16961 serogroup O1)	0.0	[66..760]	[3..680]
gi\|451277 - gi\|451277\|gb\|AAA16155.1\| oligopeptidase A [Escherichia coli]	0.0	[80..757]	[3..677]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[80..757]	[3..677]
gi\|165915120, gi... - gi\|89105112\|ref\|ZP_01177638.1\| COG0339: Zn-dependent oligopeptidases [Yersinia pestis biovar Orienta... gi\|229691095, gi... - gi\|229841756\|ref\|ZP_04461912.1\| oligopeptidase A [Yersinia pestis biovar Orientalis str. India 195],... gi\|108781706, gi... - gi\|108809793\|ref\|YP_653709.1\| oligopeptidase A [Yersinia pestis Antiqua], gi\|108781706\|gb\|ABG15764.1... gi\|229696039, gi... - gi\|229839673\|ref\|ZP_04459832.1\| oligopeptidase A [Yersinia pestis biovar Orientalis str. PEXU2], gi\|... gi\|229678412, gi... - gi\|229904294\|ref\|ZP_04519405.1\| oligopeptidase A [Yersinia pestis Nepal516], gi\|229678412\|gb\|EEO7451... gi\|229706515, gi... - gi\|229836447\|ref\|ZP_04456614.1\| oligopeptidase A [Yersinia pestis Pestoides A], gi\|229706515\|gb\|EEO9... gi\|162353098, gi... - gi\|77635480\|ref\|ZP_00797564.1\| COG0339: Zn-dependent oligopeptidases [Yersinia pestis Angola], gi\|16... gi\|165926985, gi... - gi\|165926985\|ref\|ZP_02222817.1\| oligopeptidase A [Yersinia pestis biovar Orientalis str. F1991016], ... gi\|166009704, gi... - gi\|166009704\|ref\|ZP_02230602.1\| oligopeptidase A [Yersinia pestis biovar Antiqua str. E1979001], gi\|... gi\|166205336, gi... - gi\|166213395\|ref\|ZP_02239430.1\| oligopeptidase A [Yersinia pestis biovar Antiqua str. B42003004], gi... gi\|150261069, gi... - gi\|150261069\|ref\|ZP_01917797.1\| oligopeptidase A [Yersinia pestis CA88-4125], gi\|149290477\|gb\|EDM405... gi\|167400663, gi... - gi\|167400663\|ref\|ZP_02306172.1\| oligopeptidase A [Yersinia pestis biovar Antiqua str. UG05-0454], gi... gi\|167420890, gi... - gi\|167420890\|ref\|ZP_02312643.1\| oligopeptidase A [Yersinia pestis biovar Orientalis str. MG05-1020],... gi\|167426620, gi... - gi\|167426620\|ref\|ZP_02318373.1\| oligopeptidase A [Yersinia pestis biovar Mediaevalis str. K1973002],... gi\|145212287, gi... - gi\|145600591\|ref\|YP_001164667.1\| oligopeptidase A [Yersinia pestis Pestoides F], gi\|145212287\|gb\|ABP... gi\|21960848, gi\|... - gi\|22127726\|ref\|NP_671149.1\| oligopeptidase A [Yersinia pestis KIM], gi\|21960848\|gb\|AAM87400.1\|AE013... gi\|25319701 - pir\|\|AH0483 oligopeptidase A (EC 3.4.24.70) [imported] - Yersinia pestis (strain CO92) gi\|15981883, gi\|... - gi\|218930970\|ref\|YP_002348845.1\| oligopeptidase A [Yersinia pestis CO92], gi\|16124102\|ref\|NP_407415.... gi\|45443086, gi\|... - gi\|45443086\|ref\|NP_994625.1\| oligopeptidase A [Yersinia pestis biovar Microtus str. 91001], gi\|45437...	0.0	[77..757]	[11..677]

Back

Predicted Domain #1

Region A:
Residues: [1-84]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRTIILKAG SNASIPSPSR QNKLLRFFAT AGAVSRTSPG SIKKIFDDNS YWRNINGQDA  60
   61 NNSKISQYLF KKNKTGLFKN PYLT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [85-412]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPDGLRKFSQ VSLQQAQELL DKMRNDFSES GKLTYIMNLD RLSDTLCRVI DLCEFIRSTH  60
   61 PDDAFVRAAQ DCHEQMFEFM NVLNTDVSLC NILKSVLNNP EVSSKLSAEE LKVGKILLDD 120
  121 FEKSGIYMNP DVREKFIQLS QEISLVGQEF INHTDYPGSN SVKIPCKDLD NSKVSTFLLK 180
  181 QLNKDVKGQN YKVPTFGYAA YALLKSCENE MVRKKLWTAL HSCSDKQVKR LSHLIKLRAI 240
  241 LANLMHKTSY AEYQLEGKWQ DRRCQDFILT LMNNTIEKTA NELKFIAELK AKDLKKPLTT 300
  301 NTDEILKLVR PWDRDYYTGK YFQLNPSN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [628-698]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLQNCETYSQ AKMAMLDQSF HDEKIISDID NFDVVENYQA LERRLKVLVD DQSNWCGRFG  60
   61 HLFGSGQLIT A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1300.0
Match:	1i1iP_
Description:	Neurolysin (endopeptidase 24.16)
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [413-627]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPNAKEISYY FTLGNVIQGL SDLFQQIYGI RLEPAITDEG ETWSPDVRRL NVISEEEGII  60
   61 GIIYCDLFER NGKTSNPAHF TVCCSRQIYP SETDFSTIQV GENPDGTYFQ LPVISLVCNF 120
  121 SPILIASKKS LCFLQLSEVE TLFHEMGHAM HSMLGRTHMQ NISGTRCATD FVELPSILME 180
  181 HFAKDIRILT KIGKHYGTGE TIQADMLQRF MKSTN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [699-770]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TYFDRTIASK IWYALFEDDP YSRKNGDKFK KHLLKWGGLK DPWKCIADVL ECPMLEKGGS  60
   61 DAMEFIAQSH KS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1300.0
Match:	1i1iP_
Description:	Neurolysin (endopeptidase 24.16)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits