| Protein: | IML1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1584 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IML1.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1584] | [1..1584] |
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0.0 | [840..1569] | [753..1462] |
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0.0 | [881..1575] | [427..1157] |
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0.0 | [105..522] | [8..425] |
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0.0 | [882..1574] | [1091..1857] |
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3.0E-63 | [1114..1348] | [302..570] |
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5.0E-60 | [1114..1345] | [301..583] |
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Region A: Residues: [1-113] |
1 11 21 31 41 51
| | | | | |
1 MFAKLHGKKQ RPISSINSQT PRTSNTTHAN SISLSSGNLI VGSNRNLRQK KEQFGSQQRA 60
61 SGRKLISNKE NDDNVNNGGD NNYDNGERVH RHHIPGLKIK AYQAELGYHE SRF
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.374 | 0.958 | fungal-type vacuole membrane | d.189.1 | PX domain |
| View | Download | 0.237 | 0.958 | fungal-type vacuole membrane | b.43.4 | Riboflavin synthase domain-like |
| View | Download | 0.255 | 0.958 | fungal-type vacuole membrane | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.292 | 0.958 | fungal-type vacuole membrane | c.97.1 | Cytidine deaminase-like |
| View | Download | 0.374 | 0.958 | fungal-type vacuole membrane | d.189.1 | PX domain |
| View | Download | 0.292 | 0.958 | fungal-type vacuole membrane | c.97.1 | Cytidine deaminase-like |
| View | Download | 0.255 | 0.958 | fungal-type vacuole membrane | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.237 | 0.958 | fungal-type vacuole membrane | b.43.4 | Riboflavin synthase domain-like |
|
Region A: Residues: [114-573] |
1 11 21 31 41 51
| | | | | |
1 SENLVMLNLV EFPDIKPGDL VELKTYHKNP SASNGDKKIY FIAKDFDGET KRRAKTSNVS 60
61 ILSGQLQTLL DLPSRSRIWI KLKPNKFDLQ ADVVEFNIKD CLLNRGDMWV LSSKLVDTCV 120
121 FMDQRLAFLD SIRGTIKGIY RNGKKIVSGY IGEQTRIIFR SESARLIFLI QITDEMWNFE 180
181 ETGEQLFQKM VNSFFPKIFK KWKDVDTHHT ITIAFAISMD LSDTSFKDLT PGESLKNSQD 240
241 YFRIVVDQVS IIHWVDIMET LREEFMEIRK DLLNKQTDKG YSVANGRFSP VIKSNFLELV 300
301 NFATTILTDP FKQLDLRHTT THVMIISPGS GLFDVDYSLL RLTGKKLLSL EMTMDLICLS 360
361 KAPLHIVPLF RYRDFENKLH HCVPLWLSVF FWNDHDKKSN SEWTPRCKIY DLQMMGITEN 420
421 ELIREVDVEY LQLNKKVKSL SEFMNDYDKN AFEVKILCAG
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [574-852] |
1 11 21 31 41 51
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1 SNTKQSKKLN SKFDTVFEND VVVKARKIPA TATTTHGNTK FIWRGPKVAL PAIKDIQKPN 60
61 VIPDLSIKTI EASFYDDCNT TNDKISTPTT SNNDNLEMND SLVSVRSADN QNTSLALDSL 120
121 KGLSKRNSLK DFTQRVITKF ISNIDTSKNK KIKSTLLRDD VDNSPLGSNT PLPSSESKIS 180
181 GLKLQQKGLA DENVISKRGN LIIKKNLSIF GLPSNEIMSG SPSSYLGSSH TRTSSKLSNM 240
241 SDKAAFITEG QKSKHDDSNT YSLTQQLKHR ISETWVDIK
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [853-953] |
1 11 21 31 41 51
| | | | | |
1 SPSIPVSSEF ANELLPIRWK DVWPKYVARK YSKWRSFTTP AELPITISDF PSKDDFDRNF 60
61 IFRNHSVTLN TDQEQYNQTY KDLLRDMIYM RLLTGFQICV G
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.404 | 0.488 | fungal-type vacuole membrane | a.39.1 | EF-hand |
| View | Download | 0.615 | 0.015 | fungal-type vacuole membrane | a.118.14 | FliG |
| View | Download | 0.376 | 0.005 | fungal-type vacuole membrane | d.129.4 | Cell-division protein ZipA, C-terminal domain |
| View | Download | 0.578 | N/A | N/A | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.363 | N/A | N/A | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.350 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.341 | N/A | N/A | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.339 | N/A | N/A | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.334 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.312 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.286 | N/A | N/A | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.285 | N/A | N/A | d.45.1 | ClpS-like |
| View | Download | 0.284 | N/A | N/A | a.156.1 | S13-like H2TH domain |
| View | Download | 0.281 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.269 | N/A | N/A | a.28.2 | Colicin E immunity proteins |
| View | Download | 0.261 | N/A | N/A | a.54.1 | Domain of early E2A DNA-binding protein, ADDBP |
| View | Download | 0.259 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.255 | N/A | N/A | a.130.1 | Chorismate mutase II |
| View | Download | 0.251 | N/A | N/A | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.242 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.240 | N/A | N/A | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.235 | N/A | N/A | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.232 | N/A | N/A | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.230 | N/A | N/A | a.60.2 | RuvA domain 2-like |
| View | Download | 0.203 | N/A | N/A | a.26.1 | 4-helical cytokines |
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Region A: Residues: [954-1170] |
1 11 21 31 41 51
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1 RQVEKIELSR ESGESETVVN KYLDFNQNDA FKLYLMIDSE IHRITCSSSG IIDVERYLRK 60
61 DEANLFDQVP SYIPLVKTRY ESSFRDAMID PLHVKRESLN WNQIDQVLAG YGDNLIDRKW 120
121 HGFRAKYVVL PTDIPPNTYS MVINGKSETL NPEEIRVEGL RRLIGSITRS RLRTEKEKKG 180
181 RKTKREEIQP EVMFYTGPLY NFINEQQTSL ESSAINF
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1171-1304] |
1 11 21 31 41 51
| | | | | |
1 KDSIFVNDNN LLNRNVELSK LAYQIQRGED RITLVNRKWH WKKHEKCFVG SEMVNWLIRN 60
61 FSDIDTREDA IKYGQKVMKE GLFVHVLNKH NFLDGHYFYQ FSPEYVMDTN KLEKTNSHRS 120
121 TLSDPKQMLR KAST
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| Detection Method: | |
| Confidence: | 50.70927 |
| Match: | 1fshA_ |
| Description: | Segment polarity protein Dishevelled-1 |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [1305-1584] |
1 11 21 31 41 51
| | | | | |
1 GSSNDPSAMT PFSSVVPAIS ASNASVADAK EPSRPILMLS NSLVIDVDPA GKSSKQESCT 60
61 VHYDRVHNPD HCFHIRLEWL TTTPKLIDDL VGNWSRLCER YGLKMIEIPW EELCTIPSVN 120
121 PFHSFVEIKL AINPWEDPEF KDRELFAKSK FYYHVYLLKA SGFLLDNRAS KFLQNQDIEF 180
181 DIMYSWGKPQ FKYVQYIHHT GAYVAELREN GCLFLAPNNI YISRVNPGNI IGKIHSASSS 240
241 SLDAQKVILN FKSTCLDYQK LRSIFLDAKE MWITGKIVED
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.615 | a.118.14 | FliG |
| View | Download | 0.578 | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.545 | a.118.14 | FliG |
| View | Download | 0.404 | a.39.1 | EF-hand |
| View | Download | 0.378 | a.118.14 | FliG |
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Region A: Residues: [960-1151] |
1 11 21 31 41 51
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1 ELSRESGESE TVVNKYLDFN QNDAFKLYLM IDSEIHRITC SSSGIIDVER YLRKDEANLF 60
61 DQVPSYIPLV KTRYESSFRD AMIDPLHVKR ESLNWNQIDQ VLAGYGDNLI DRKWHGFRAK 120
121 YVVLPTDIPP NTYSMVINGK SETLNPEEIR VEGLRRLIGS ITRSRLRTEK EKKGRKTKRE 180
181 EIQPEVMFYT GP
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1152-1274] |
1 11 21 31 41 51
| | | | | |
1 LYNFINEQQT SLESSAINFK DSIFVNDNNL LNRNVELSKL AYQIQRGEDR ITLVNRKWHW 60
61 KKHEKCFVGS EMVNWLIRNF SDIDTREDAI KYGQKVMKEG LFVHVLNKHN FLDGHYFYQF 120
121 SPE
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| Detection Method: | |
| Confidence: | 27.0 |
| Match: | 1o7fA |
| Description: | Regulatory domain of epac2, domain 2; Regulatory domain of Epac2, domains 1 and 3 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.72090787140675 | bayes_pls_golite062009 |
| transcription regulator activity | 1.59132356860747 | bayes_pls_golite062009 |
| nucleic acid binding | 1.5215255296187 | bayes_pls_golite062009 |
| DNA binding | 1.50188209285697 | bayes_pls_golite062009 |
| transcription factor activity | 0.761675280117783 | bayes_pls_golite062009 |
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Region A: Residues: [1275-1337] |
1 11 21 31 41 51
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1 YVMDTNKLEK TNSHRSTLSD PKQMLRKAST GSSNDPSAMT PFSSVVPAIS ASNASVADAK 60
61 EPS
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1338-1480] |
1 11 21 31 41 51
| | | | | |
1 RPILMLSNSL VIDVDPAGKS SKQESCTVHY DRVHNPDHCF HIRLEWLTTT PKLIDDLVGN 60
61 WSRLCERYGL KMIEIPWEEL CTIPSVNPFH SFVEIKLAIN PWEDPEFKDR ELFAKSKFYY 120
121 HVYLLKASGF LLDNRASKFL QNQ
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1481-1584] |
1 11 21 31 41 51
| | | | | |
1 DIEFDIMYSW GKPQFKYVQY IHHTGAYVAE LRENGCLFLA PNNIYISRVN PGNIIGKIHS 60
61 ASSSSLDAQK VILNFKSTCL DYQKLRSIFL DAKEMWITGK IVED
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
