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View Structure Prediction Details

Protein: SOD1
Organism: Saccharomyces cerevisiae
Length: 154 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SOD1.

Description E-value Query
Range		 Subject
Range
gi|5353561 - gi|5353561|gb|AAD42179.1| superoxide dismutase/HCV major epitope fusion protein [synthetic construct...
 2.0E-66 [3..152] [4..152]
gi|218564 - gi|218564|dbj|BAA14373.1| unnamed protein product [Schizosaccharomyces pombe]
 2.0E-60 [3..152] [3..151]
SODC_YEAST - Superoxide dismutase [Cu-Zn] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SOD1 PE=1 S...
gi|151945169 - gi|151945169|gb|EDN63420.1| Cu, Zn superoxide dismutase [Saccharomyces cerevisiae YJM789]
SOD1 - Cytosolic copper-zinc superoxide dismutase; some mutations are analogous to those that cause ALS (am...
 4.0E-60 [1..154] [1..154]
SODC1_DEBHA - Superoxide dismutase [Cu-Zn] 1 OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NB...
SODC1_DEBHA - Superoxide dismutase [Cu-Zn] 1 OS=Debaryomyces hansenii GN=SOD1 PE=1 SV=4
 1.0E-59 [1..154] [1..154]
SODC_CANAX - Superoxide dismutase [Cu-Zn] OS=Candida albicans GN=SOD1 PE=3 SV=3
gi|238881608 - gi|238881608|gb|EEQ45246.1| superoxide dismutase 1 [Candida albicans WO-1]
 1.0E-59 [1..153] [1..153]
SODC_CRYGA - Superoxide dismutase [Cu-Zn] OS=Cryptococcus gattii GN=SOD1 PE=2 SV=3
SODC_CRYGA - Superoxide dismutase [Cu-Zn] - Cryptococcus gattii (Filobasidiella gattii) (Cryptococcus bacillispor...
SODC_CRYGA - Superoxide dismutase [Cu-Zn] OS=Cryptococcus gattii GN=SOD1 PE=2 SV=3
 2.0E-59 [1..154] [1..154]
gi|5689611 - gi|5689611|emb|CAB51840.1| copper/zinc superoxide dismutase [Arabidopsis thaliana]
 5.0E-59 [3..153] [66..214]
gi|13603739, gi|... - gi|13603739|gb|AAK31917.1|AF248048_1 copper zinc superoxide dismutase [Cryptococcus neoformans var. ...
gi|58266258, gi|... - gi|58266258|ref|XP_570285.1| copper zinc superoxide dismutase [Cryptococcus neoformans var. neoforma...
 6.0E-59 [1..152] [1..152]

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Predicted Domain #1
Region A:
Residues: [1-154] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQAVAVLKG DAGVSGVVKF EQASESEPTT VSYEIAGNSP NAERGFHIHE FGDATNGCVS  60
   61 AGPHFNPFKK THGAPTDEVR HVGDMGNVKT DENGVAKGSF KDSLIKLIGP TSVVGRSVVI 120
  121 HAGQDDLGKG DTEESLKTGN AGPRPACGVI GLTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 812.70927
Match: 1b4lA_
Description: Cu,Zn superoxide dismutase, SOD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein phosphatase 2B binding 13.5719110466797 bayes_pls_golite062009
superoxide dismutase activity 12.1093323949609 bayes_pls_golite062009
oxidoreductase activity, acting on superoxide radicals as acceptor 12.1093323949609 bayes_pls_golite062009
chaperone binding 5.11696266714142 bayes_pls_golite062009
superoxide dismutase copper chaperone activity 4.90125496493753 bayes_pls_golite062009
copper ion binding 4.51765925795625 bayes_pls_golite062009
protein phosphatase binding 3.26481550276071 bayes_pls_golite062009
phosphatase binding 3.1414149853516 bayes_pls_golite062009
transition metal ion binding 2.451533032488 bayes_pls_golite062009
binding 2.28211284921339 bayes_pls_golite062009
protein binding 1.96660745768497 bayes_pls_golite062009
enzyme binding 1.82618630359051 bayes_pls_golite062009
cation binding 1.79413011653575 bayes_pls_golite062009
metal ion binding 1.79413011653575 bayes_pls_golite062009
ion binding 1.78699219376941 bayes_pls_golite062009
catalytic activity 1.09233965765942 bayes_pls_golite062009
copper ion transmembrane transporter activity 0.658369569046781 bayes_pls_golite062009
metallochaperone activity 0.515959593535099 bayes_pls_golite062009
copper chaperone activity 0.412497194733789 bayes_pls_golite062009
ion transmembrane transporter activity 0.32642292951469 bayes_pls_golite062009
cation transmembrane transporter activity 0.262312399748454 bayes_pls_golite062009
zinc ion binding 0.25600715352161 bayes_pls_golite062009
antioxidant activity 0.240491838042064 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle