| Protein: | GEA1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1408 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GEA1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1408] | [1..1408] |
|
|
0.0 | [15..1407] | [32..1388] |
|
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0.0 | [15..1407] | [32..1388] |
|
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0.0 | [214..1396] | [326..1497] |
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|
0.0 | [214..1396] | [326..1497] |
|
Region A: Residues: [1-521] |
1 11 21 31 41 51
| | | | | |
1 MHDVPMETVL AVNPATMIVK ECINLCSAMN KQSRDKSQTS VAALLGGGSD IFLSQSDSFV 60
61 DSFHNLPTSS YHDPLISGLV QLRLKINDLK GLDSLNALEL LKPFLEIVSA SSVSGYTTSL 120
121 ALDSLQKVFT LKIINKTFND IQIAVRETVV ALTHCRFEAS KQISDDSVLL KVVTLLRDII 180
181 TSSFGDYLSD TIIYDVLQTT LSLACNTQRS EVLRKTAEVT IAGITVKLFT KLKLLDPPTK 240
241 TEKYINDESY TDNNLKDDII GTTTSDNDLS STDDDSAVAD DNKNEKPVQQ VIREQENDEE 300
301 TAEKAENVEP NYGITVIKDY LGLLLSLVMP ENRMKHTTSA MKLSLQLINA AIEISGDKFP 360
361 LYPRLFSLIS DPIFKSVLFI IQSSTQYSLL QATLQLFTSL VVILGDYLPM QIELTLRRIF 420
421 EILEDTTISG DVSKQKPPAI RELIIEQLSI LWIHSPAFFL QLFVNFDCNL DRSDLSIDFI 480
481 KELTKFSLPA AAVNTSNNIP PICLEGVLSL IENIYNDLQR F
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [522-608] |
1 11 21 31 41 51
| | | | | |
1 DRAEFVKNQK EIDILKQRDR KTEFILCVET FNEKAKKGIQ MLIEKGFIDS DSNRDIASFL 60
61 FLNNGRLNKK TIGLLLCDPK KTSLLKE
|
| Detection Method: | |
| Confidence: | 918.154902 |
| Match: | 1ku1A_ |
| Description: | ARF guanine-exchange factor 2, Gea2 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [609-758] |
1 11 21 31 41 51
| | | | | |
1 FIDLFDFKGL RVDEAIRILL TKFRLPGESQ QIERIVEAFS SKYSADQSND KVELEDKKAG 60
61 KNGSESMTED DIIHVQPDAD SVFVLSYSII MLNTDSHNPQ VKDHMTFDDY SNNLRGCYNG 120
121 KDFPRWYLHK IYTSIKVKEI VMPEEHHGNE
|
| Detection Method: | |
| Confidence: | 918.154902 |
| Match: | 1ku1A_ |
| Description: | ARF guanine-exchange factor 2, Gea2 |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ARF guanyl-nucleotide exchange factor activity | 6.57705646633597 | bayes_pls_golite062009 |
| GTPase regulator activity | 3.37865780899325 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 3.23621073985922 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 3.11224105598265 | bayes_pls_golite062009 |
| small GTPase regulator activity | 2.75174745190211 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.95578809138334 | bayes_pls_golite062009 |
| binding | 1.3334812784277 | bayes_pls_golite062009 |
| protein binding | 0.917306986228715 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.909190013421997 | bayes_pls_golite062009 |
| phosphoinositide binding | 0.0750646331148792 | bayes_pls_golite062009 |
| phospholipid binding | 0.0172309833091902 | bayes_pls_golite062009 |
|
Region A: Residues: [759-819] |
1 11 21 31 41 51
| | | | | |
1 RWFEDAWNNL ISSTSVMTEM QRDFTNPISK LAQIDILQYE KAIFSNVRDI ILKTLFKIFT 60
61 V
|
| Detection Method: | |
| Confidence: | 3.39794 |
| Match: | 1fhwA_ |
| Description: | Grp1 |
Matching Structure (courtesy of the PDB): |
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|
Region A: Residues: [820-1048] |
1 11 21 31 41 51
| | | | | |
1 ASSDQISLRI LDAISKCTFI NYYFSFDQSY NDTVLHLGEM TTLAQSSAKA VELDVDSIPL 60
61 VEIFVEDTGS KISVSNQSIR LGQNFKAQLC TVLYFQIIKE ISDPSIVSTR LWNQIVQLIL 120
121 KLFENLLMEP NLPFFTNFHS LLKLPELPLP DPDISIRKAK MSRSLLSTFA SYLKGDEEPS 180
181 EEDIDFSIKA FECVKASHPL SSVFENNQLV SPKMIETLLS SLVIEKTSE
|
| Detection Method: | |
| Confidence: | 8.25 |
| Match: | 1b3uA |
| Description: | Constant regulatory domain of protein phosphatase 2a, pr65alpha |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1049-1116] |
1 11 21 31 41 51
| | | | | |
1 NSPYFEQELL FLLEISIILI SEASYGQEFG ALIADHMINI SNLDGLSKEA IARLASYKMF 60
61 LVSRFDNP
|
| Detection Method: | |
| Confidence: | 8.25 |
| Match: | 1b3uA |
| Description: | Constant regulatory domain of protein phosphatase 2a, pr65alpha |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1117-1408] |
1 11 21 31 41 51
| | | | | |
1 RDILSDLIEH DFLVKNEIFN TKYYESEWGK QVINDLFTHL NDVKYNERAL KNVKFWNFLR 60
61 ILISAKDRQF AVYTFLEKYI QNGDIFVDDG NFMNILSLLD EMSCAGAVGT KWEQNYENSV 120
121 EDGCEAPESN PYRSIIDLSS RSINITADLL STVGRSNSAL NKNEIIAAIQ GLAHQCLNPC 180
181 DELGMQALQA LENILLSRAS QLRTEKVAVD NLLETGLLPI FELDEIQDVK MKRITSILSV 240
241 LSKIFLGQLV EGVTSNETFL RVLNVFNKYV DDPTVERQLQ ELIISKREIE KE
|
| Detection Method: | |
| Confidence: | 8.25 |
| Match: | 1b3uA |
| Description: | Constant regulatory domain of protein phosphatase 2a, pr65alpha |
| Matching Structure (courtesy of the PDB): |
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