YRC Public Data Repository - Protein Structure Prediction

Protein:	YJR008W
Organism:	Saccharomyces cerevisiae
Length:	338 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJR008W.

Description	E-value	Query Range	Subject Range
YJX8_YEAST - MEMO1 family protein YJR008W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YJR008W PE=... YJR008W - Putative protein of unknown function; expression repressed by inosine and choline in an Opi1p-depend...	0.0	[1..338]	[1..338]
gi\|114576869 - gi\|114576869\|ref\|XP_001164110.1\| PREDICTED: chromosome 2 open reading frame 4 isoform 3 [Pan troglod... MEMO1 - mediator of cell motility 1 gi\|123982438, gi... - gi\|123997099\|gb\|ABM86151.1\| chromosome 2 open reading frame 4 [synthetic construct], gi\|123982438\|gb... gi\|126303134 - gi\|126303134\|ref\|XP_001371460.1\| PREDICTED: similar to CGI-27 protein [Monodelphis domestica] MEMO1_MACFA - Protein MEMO1 OS=Macaca fascicularis GN=MEMO1 PE=2 SV=1	2.0E-99	[4..337]	[8..296]
MEMO1_MOUSE - Protein MEMO1 OS=Mus musculus GN=Memo1 PE=1 SV=1	6.0E-99	[4..337]	[8..296]
SPAC4H3.04c - UPF0103 family YAY4_SCHPO - MEMO1 family protein C4H3.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC4H3.04c ...	2.0E-94	[2..333]	[4..307]
Y539_PYRAB - MEMO1 family protein PYRAB05390 OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PYRAB05390 PE=3 SV=1 Y539_PYRAB - UPF0103 protein PYRAB05390 OS=Pyrococcus abyssi GN=PYRAB05390 PE=3 SV=1	2.0E-88	[3..335]	[2..289]
tag-253 - status:Confirmed UniProt:Q22915 protein_id:AAM29667.1	3.0E-87	[4..318]	[11..280]
gi\|25412293, gi\|... - gi\|4567249\|gb\|AAD23663.1\| expressed protein [Arabidopsis thaliana], pir\|\|E84646 hypothetical protein...	1.0E-85	[2..325]	[3..277]
gi\|3258055, gi\|1... - gi\|3258055\|dbj\|BAA30738.1\| 294aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14591400\|... gi\|7449984 - gi\|7449984\|pir\|\|B71042 hypothetical protein PH1626 - Pyrococcus horikoshii	2.0E-85	[3..335]	[5..292]
YG38_PYRFU, Y163... - (Q8U0F2) Hypothetical UPF0103 protein PF1638, UPF0103 protein PF1638 OS=Pyrococcus furiosus GN=PF163... Y1638_PYRFU - MEMO1 family protein PF1638 OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) G...	2.0E-83	[3..335]	[2..289]
Y045_METTH - MEMO1 family protein MTH_45 OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 ... gi\|7388365, gi\|7... - gi\|7449979\|pir\|\|G69158 conserved hypothetical protein MTH45 - Methanobacterium thermoautotrophicum (...	1.0E-78	[3..331]	[2..274]

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Predicted Domain #1

Region A:
Residues: [1-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIRPATHAG SWYSNRAQEL SQQLHTYLIK STLKGPIHNA RIIICPHAGY RYCGPTMAYS  60
   61 YASLDLNRNV KRIFILGPSH HIYFKNQILV SAFSELETPL GNLKVDTDLC KTLIQKEYPE 120
  121 NGKKLFKPMD HDTDMAEHSL EMQLPMLVET LKWREISLDT VKVFPMMVSH NSVDVDRCIG 180
  181 NILSEYIKDP NNLFIVSSDF CHWGRRFQYT GYV

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	12.21
Match:	1b4uB
Description:	LigB subunit of an aromatic-ring-opening dioxygenase LigAB
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [214-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSKEELNDAI QEETEVEMLT ARSKLSHHQV PIWQSIEIMD RYAMKTLSDT PNGERYDAWK  60
   61 QYLEITGNTI CGEKPISVIL SALSKIRDAG PSGIKFQWPN YSQSSHVTSI DDSSVSYASG 120
  121 YVTIG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits